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Lasse Sinkkonen
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| Faculté ou Centre | Faculté des Sciences, des Technologies et de Médecine | ||||
| Department | Département Sciences de la vie et médecine | ||||
| Adresse postale |
Université du Luxembourg 6, avenue du Swing L-4367 Belvaux |
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| Bureau sur le campus | BioTech II, 4.23 | ||||
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| Téléphone | (+352) 46 66 44 6839 | ||||
- Principal Investigator (ORCID ID)
- Vice-Study Director of the International Master of Science in Biomedicine
Last updated on: lundi 01 mars 2021
2022
Focal adhesion kinase plays a dual role in TRAIL resistance and metastatic outgrowth of malignant melanoma; ; ; ; ; ; ; ; ; ;
in Cell Death and Disease (2022)
2021
ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1; ; ; ; ; ; ; ; ; ; ;
in Frontiers in Oncology (2021)
Single‑nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell‑type‑specific gene regulatory variation; ; ; ; ; ; ; ;
in Epigenetics and Chromatin (2021)
Nanopore Single-Molecule Sequencing for Mitochondrial DNA Methylation Analysis: Investigating Parkin-Associated Parkinsonism as a Proof of Concept; ; ; ; ; ; ; ; ;
in Frontiers in Aging Neuroscience (2021)
Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targeting; ; ; ; ; ; ; ; ; ; ; ; ; ; ;
in Cell Death and Differentiation (2021)
Quantitative trait locus mapping identifies a locus linked to striatal dopamine and points to collagen IV alpha-6 chain as a novel regulator of striatal axonal branching in mice; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ;
in Genes, Brain, and Behavior (2021)
The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ;
in Cell Reports (2021)
2020
Pituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ;
in Frontiers in Genetics (2020)
Reduced sialylation triggers homeostatic synapse and neuronal loss in middle-aged mice; ; ; ; ; ; ; ; ; ; ;
in Neurobiology of Aging (2020)
Missing heritability in Parkinson’s disease: the emerging role of non‑coding genetic variation; ; ;
in Journal of Neural Transmission (2020)
2019
Identification of genes under dynamic post-transcriptional regulation from time-series epigenomic data; ; ; ;
in Epigenomics (2019)
Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ;
in Parkinsonism and Related Disorders (2019)
2018
Temporal enhancer profiling of parallel lineages identifies AHR and GLIS1 as regulators of mesenchymal multipotency; ; ; ; ; ; ; ;
in Nucleic Acids Research (2018)
2017
Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture; ; ; ; ; ; ; ;
in Nucleic Acids Research (2017)
2015
Cell type-selective disease-association of genes under high regulatory load; ; ; ;
in Nucleic Acids Research (2015), 43(18), 8839-8855
Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network; ; ; ; ; ; ; ;
in BMC Genomics (2015), 16(809),
2014
Neurodegeneration by Activation of the Microglial Complement–Phagosome Pathway; ; ; ; ; ; ; ; ; ; ;
in Journal of Neuroscience (2014), 34(25), 8546-8556
ChIP-seq profiling of the active chromatin marker H3K4me3 and PPARγ, CEBPα and LXR target genes in human SGBS adipocytes; ; ; ; ;
in Genomics Data (2014), 2
Combinatorial regulation of lipoprotein lipase by microRNAs during mouse adipogenesis; ; ; ; ;
in RNA Biology (2014), 11(1), 76-91
2013
Integrated analysis of transcript-level regulation of metabolism reveals disease-relevant nodes of the human metabolic network; ; ; ; ;
in Nucleic Acids Research (2013)
2012
Dataset integration identifies transcriptional regulation of microRNA genes by PPARgamma in differentiating mouse 3T3-L1 adipocytes; ; ; ; ;
in Nucleic Acids Research (2012), 40(10), 4446-4460
2010
Time-Resolved Expression Profiling of the Nuclear Receptor Superfamily in Human Adipogenesis; ; ; ;
in PLoS ONE (2010), 5(9),
Dicer is associated with ribosomal DNA chromatin in mammalian cells; ; ;
in PLoS ONE (2010), 5(8), 1-2
2008
MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells; ; ; ; ; ; ; ;
in Nature Structural and Molecular Biology (2008), 15(3), 259-67
2005
Regulation of the human cyclin C gene via multiple vitamin D3-responsive regions in its promoter; ; ; ;
in Nucleic Acids Research (2005), 33(8), 2440-51
Spatio-temporal activation of chromatin on the human CYP24 gene promoter in the presence of 1alpha,25-Dihydroxyvitamin D3; ; ; ;
in Journal of Molecular Biology (2005), 350(1), 65-77
