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Dr. Christiane Wurth-Margue

Christiane Wurth-Margue

Research scientist

Faculté ou Centre Faculté des Sciences, des Technologies et de Médecine
Department Département Sciences de la vie et médecine
Adresse postale Université du Luxembourg
6, avenue du Swing
L-4367 Belvaux
Bureau sur le campus BioTech II, 4.25
Téléphone (+352) 46 66 44 6433
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See detailCross-Linking Ligation and Sequencing of Hybrids (qCLASH) Reveals an Unpredicted miRNA Targetome in Melanoma Cells
Kozar, Ines; Philippidou, Demetra; Margue, Christiane; Gay, Lauren; Renne, Rolf; Kreis, Stephanie

in Cancers (2021)

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See detailNRAS mutant melanoma: Towards better therapies
Randic, Tijana; Kozar, Ines; Margue, Christiane; Utikal, Jochen; Kreis, Stephanie

in Cancer Treatment Reviews (2021), 99

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See detailSystematic transcriptional profiling of responses to STAT1- and STAT3- activating cytokines in different cancer types
Kirchmeyer, Mélanie; Servais, Florence; Ginolhac, Aurélien; Nazarov, Petr V.; Margue, Christiane; Philippidou, Demetra; Nicot, Nathalie; Behrmann, Iris; Haan, Claude; Kreis, Stephanie

in Journal of Molecular Biology (2020)

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See detailHypoxia-Induced Adaptations of miRNomes and Proteomes in Melanoma Cells and Their Secreted Extracellular Vesicles
Walbrecq, Geoffroy; Lecha, Odile; Gaigneaux, Anthoula; Fougeras, Miriam R .; Philippidou, Demetra; Margue, Christiane; Tetsi Nomigni, Milène; Bernardin, François; Dittmar, Gunnar; Behrmann, Iris; Kreis, Stephanie

in Cancers (2020)

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See detailDistinct Cargos of Small Extracellular Vesicles Derived from Hypoxic Cells and Their Effect on Cancer Cells
Walbrecq, Geoffroy; Margue, Christiane; Behrmann, Iris; Kreis, Stephanie

in International Journal of Molecular Sciences (2020)

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See detailMany ways to resistance: How melanoma cells evade targeted therapies
Kozar, Ines; Margue, Christiane; Rothengatter, Sonja; Haan, Claude; Kreis, Stephanie

in Biochimica et Biophysica Acta - Reviews on Cancer (2019), 1871(2), 313-322

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See detailKinase inhibitor library screening identifies synergistic drug combinations effective in sensitive and resistant melanoma cells
Margue, Christiane; Philippidou, Demetra; Kozar, Ines; Cesi, Giulia; Felten, Paul; Kulms, Dagmar; Letellier, Elisabeth; Haan, Claude; Kreis, Stephanie

in Journal of Experimental and Clinical Cancer Research (2019), 38(1),

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See detailThe PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by a-PD-L1 or a-IL6 antibodies
Rolvering, Catherine; Zimmer, Andreas David; Ginolhac, Aurélien; Margue, Christiane; Kirchmeyer, Mélanie; Servais, Florence; Hermanns, Heike M.; Hergovits, Sabine; Nazarov, Petr V.; Nicot, Nathalie; Kreis, Stephanie; Haan, Serge; Behrmann, Iris; Haan, Claude

in Journal of Leukocyte Biology (2018), 104

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See detailImpact of BRAF kinase inhibitors on the miRNomes and transcriptomes of melanoma cells
Kreis, Stephanie; Kozar, Ines; Cesi, Giulia; Margue, Christiane; Philippidou, Demetra

in Biochimica et Biophysica Acta (2017)

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See detailTransferring intercellular signals and traits between cancer cells: extracellular vesicles as "homing pigeons"
Cesi, Giulia; Walbrecq, Geoffroy; Margue, Christiane; Kreis, Stephanie

in Cell Communication and Signaling (2016), 14(1), 13

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See detailThe TAT-RasGAP317-326 anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner
Heulot, Mathieu; Chevalier, Nadja; Puyal, Julien; Margue, Christiane; Michel, Sébastien; Kreis, Stephanie; Kulms, Dagmar; Barras, David; Nahimana, Aimable; Widmann, Christian

in Oncotarget (2016), 7(39),

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See detailCirculating microRNAs as candidate biomarkers for the surveillance of melanoma patients
Behrmann, Iris; Margue, Christiane; Kreis, Stephanie

in EBioMedicine (2015)

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See detailComparison of a healthy miRNome with melanoma patient miRNomes: are microRNAs suitable serum biomarkers for cancer?
Margue, Christiane; Reinsbach, Susanne; Philippidou, Demetra; Beaume, Nicolas; Walters, Casandra; Schneider, Jochen; Nashan, Dorothee; Behrmann, Iris; Kreis, Stephanie

in Oncotarget (2015), 6(14), 12110-27

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See detailNew Target Genes of MITF-Induced microRNA-211 Contribute to Melanoma Cell Invasion
Margue, Christiane; Philippidou, Demetra; Reinsbach, Susanne; Schmitt, Martina; Behrmann, Iris; Kreis, Stephanie

in PLoS ONE (2013), 8(9),

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See detailInterferon-γ-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells
Schmitt, Martina J.; Philippidou, Demetra; Reinsbach, Susanne; Margue, Christiane; Wienecke-Baldacchino, Anke; Nashan, Dorothee; Behrmann, Iris; Kreis, Stephanie

in Cell Communication and Signaling (2012), 10

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See detailMiRNA-29: A microRNA family with tumor-suppressing and immune-modulating properties
Schmitt, Martina; Margue, Christiane; Behrmann, Iris; Kreis, Stephanie

in Current Molecular Medicine (2012), 13(4), 572-585

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See detailIL-24: Physiological and supraphysiological effects on normal and malignant cells
Margue, Christiane; Kreis, Stephanie

in Current Medicinal Chemistry (2010), 17(29), 3318-3326

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See detailSignatures of MicroRNAs and selected MicroRNA target genes in human melanoma
Philippidou, Demetra; Schmitt, Martina; Moser, Dirk; Margue, Christiane; Nazarov, Petr V.; Muller, Arnaud; Vallar, Laurent; Nashan, Dorothee; Behrmann, Iris; Kreis, Stephanie

in Cancer Research (2010), 70(10), 4163-4173

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See detailDual role of the Jak1 FERM and kinase domains in cytokine receptor binding and in stimulation-dependent Jak activation
Haan, Serge; Margue, Christiane; Engrand, A.; Rolvering, Catherine; Schmitz-Van de Leur, H.; Heinrich, P. C.; Behrmann, Iris; Haan, Claude

in Journal of Immunology (2008), 180(2), 998-1007

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See detailIL-24: a classic cytokine and/or a potential cure for cancer?
Kreis, Stephanie; Philippidou, Demetra; Margue, Christiane; Behrmann, Iris

in Journal of Cellular and Molecular Medicine (2008), 12(6A), 2505-2510

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See detailRecombinant interleukin-24 lacks apoptosis-inducing properties in melanoma cells
Kreis, Stephanie; Philippidou, Demetra; Margue, Christiane; Rolvering, Catherine; Haan, Claude; Dumoutier, Laure; Renauld, Jean-Christophe; Behrmann, Iris

in PLoS ONE (2007), 2(12), 1300

See detailComplete loss of PTEN expression as a possible early prognostic marker for prostate cancer metastasis.
Schmitz, Martine; Grignard, Gerard; Margue, Christiane; Dippel, Walter; Capesius, Catherine; Mossong, Joel; Nathan, Michel; Giacchi, Sandro; Scheiden, Rene; Kieffer, Nelly

in International Journal of Cancer (2007), 120(6), 1284-92

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See detailJaks and cytokine receptors - an intimate relationship
Haan, Claude; Kreis, Stephanie; Margue, Christiane; Behrmann, Iris

in Biochemical Pharmacology (2006), 72(11), 1538-46

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See detailIntegrin alpha(v)beta3 expression confers on tumor cells a greater propensity to metastasize to bone.
Pecheur, Isabelle; Peyruchaud, Olivier; Serre, Claire-Marie; Guglielmi, Julien; Voland, Carole; Bourre, Francois; Margue, Christiane; Cohen-Solal, Martine; Buffet, Annie; Kieffer, Nelly; Clezardin, Philippe

in FASEB Journal (2002), 16(10), 1266-8

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See detailTranscriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHR
Margue, Christiane; Bernasconi, Michele; Barr, Frederik; Schäfer, Beat

in Oncogene (2000), 19(25), 2921

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See detailQuantification of wild-type mitochondrial DNA and its 4.8-kb deletion in rat organs.
Filser, N.; Margue, Christiane; Richter, C.

in Biochemical and biophysical research communications (1997), 233(1), 102-7

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