Dr. Dr Elisabeth Schaffner-Reckinger

Dr Elisabeth Schaffner-Reckinger

Research scientist

Faculté ou Centre Faculty of Science, Technology and Communication
Unité de recherche RU Life Sciences
Adresse postale Campus Belval, Université du Luxembourg
7, Avenue des Hauts Fourneaux
L-4362 Esch-sur-Alzette
Bureau sur le campus BioTech I, 3.05B
E-mail
Téléphone (+352) 46 66 44 6398
Fax (+352) 46 66 44 36398
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2017

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See detailThe PET and LIM1-2 domains of testin contribute to intramolecular and homodimeric interactions
Sala, Stefano; Catillon, Marie; Hadzic, Ermin; Schaffner, Elisabeth; Van Troys, Marleen; Ampe, Christophe

in PLoS ONE (2017)

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See detailExpanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations
SALA, Stefano; Van troys, Marleen; Medves, Sandrine; Catillon, Marie; Timmerman, Evy; Staes, An; Schaffner, Elisabeth; Gevaert, Kris; Ampe, Christophe

in Journal of Proteome Research (2017), doi: 10.1021/acs.jproteome.7b00034

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See detailAngiotensin II regulates phosphorylation of actin-associated proteins in human podocytes
Schenk, Laura K; Möller-Kerutt, Annika; Klosowski, Rafael; Wolters, Dirk; Schaffner, Elisabeth; Weide, Thomas; Pavenstädt, Hermann; Vollenbröker, Beate

in FASEB Journal (2017)

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2016

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See detailL-plastin Ser5 phosphorylation in breast cancer cells and in vitro is mediated by RSK downstream of the ERK/MAPK pathway
Lommel, Maiti; Trairatphisan, Panuwat; Gäbler, Karoline; Laurini, Christina; Muller, Arnaud; Kaoma, Tony; Vallar, Laurent; Sauter, Thomas; Schaffner, Elisabeth

in FASEB Journal (2016)

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2015

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See detailDelineating the Tes Interaction Site in Zyxin and Studying Cellular Effects of Its Disruption
Hadzic, Ermin; Catillon, Marie; Halavatyi, Aliaksandr; Medves, Sandrine; Van Troys, Marleen; Moes, Michèle; Baird, Michelle A; Davidson, Michael W; Schaffner, Elisabeth; Ampe, Christophe; Friederich, Evelyne

in PLoS ONE (2015)

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See detailInhibition of αIIbβ3 Ligand Binding by an αIIb Peptide that Clasps the Hybrid Domain to the βI Domain of β3
Lee, Wen Hwa; Schaffner, Elisabeth; Tsoukatos, Demokritos C; Aylward, Kelly; Moussis, Vassilios; Tsirakis, Vassilios; Trypou, Paraskevi; Egot, Marion; Baruch, Dominique; Kieffer, Nelly; Bachelot-Loza, Christilla

in PLoS ONE (2015)

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2010

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See detailQuantitative kinetic study of the actin-bundling protein L-plastin and of its impact on actin turn-over.
Al Tanoury, Ziad; Schaffner-Reckinger, Elisabeth; Halavatyi, Aliaksandr; Hoffmann, Celine; Moes, Michèle; Hadzic, Ermin; Catillon, Marie; Yatskou, Mikalai; Friederich, Evelyne

in PloS one (2010), 5(2), 9210

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See detailThe actin filament cross-linker L-plastin confers resistance to TNF-alpha in MCF-7 breast cancer cells in a phosphorylation-dependent manner.
Janji, Bassam; Vallar, Laurent; Al Tanoury, Ziad; Bernardin, Francois; Vetter, Guillaume; Schaffner-Reckinger, Elisabeth; Berchem, Guy; Friederich, Evelyne; Chouaib, Salem

in Journal of Cellular & Molecular Medicine (2010), 14(6A), 1264-75

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2009

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See detailOverexpression of the partially activated alpha(IIb)beta3D723H integrin salt bridge mutant downregulates RhoA activity and induces microtubule-dependent proplatelet-like extensions in Chinese hamster ovary cells
Schaffner-Reckinger, Elisabeth; Salsmann, Alexandre; Debili, Najet; Bellis, Julien; De Mey, Jan; Vainchenker, William; Ouwehand, Willem H.; Kieffer, Nelly

in Journal of Thrombosis and Haemostasis [=JTH] (2009), 7(7), 1207-1217

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2008

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See detailA nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the αIIbβ3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia
Ghevaert, Cedric; Salsmann, Alexandre; Watkins, Nicholas A.; Schaffner-Reckinger, Elisabeth; Rankin, Angela; Garner, Stephen F.; Stephens, Jonathan; Smith, Graham A.; Debili, Najet; Vainchenker, William; de Groot, Philip G.; Huntington, James A.; Laffan, Mike; Kieffer, Nelly; Ouwehand, Willem H.

in Blood (2008), 111(7), 3407-3414

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See detailThe talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges.
Rodius, Sophie; Chaloin, Olivier; Moes, Michèle; Schaffner-Reckinger, Elisabeth; Landrieu, Isabelle; Lippens, Guy; Lin, Minghui; Zhang, Jie; Kieffer, Nelly

in The Journal of biological chemistry (2008), 283(35), 24212-23

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2006

See detailRGD, the Rho'd to cell spreading
Salsmann, Alexandre; Schaffner-Reckinger, Elisabeth; Kieffer, Nelly

in European Journal of Cell Biology (2006), 85(3-4), 249-254

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2005

See detailA new functional role of the fibrinogen RGD motif as the molecular switch that selectively triggers integrin alphaIIbbeta3-dependent RhoA activation during cell spreading
Salsmann, Alexandre; Schaffner-Reckinger, Elisabeth; Kabile, Fabrice; Plançon, Sébastien; Kieffer, Nelly

in Journal of Biological Chemistry (2005), 280(39), 33610-33619

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2004

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See detailThe effect of recombinant IgG antibodies against the leucine-33 form of the platelet beta3 integrin (HPA-1a) on platelet function.
Joutsi-Korhonen, Lotta; Preston, Sandy; Smethurst, Peter A.; Ijsseldijk, Martin; Schaffner-Reckinger, Elisabeth; Armour, Kathryn L.; Watkins, Nicholas A.; Clark, Michael R.; de Groot, Philip G.; Farndale, Richard W.; Ouwehand, Willem H.; Williamson, Lorna M.

in Thrombosis and haemostasis (2004), 91(4), 743-54

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2003

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See detailBeta3 integrins: major therapeutic targets of the near future.
Schaffner-Reckinger, Elisabeth

in Bulletin de la Société des Sciences Médicales du Grand-Duché de Luxembourg (2003), (1), 23-34

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2002

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See detailHPA-1a phenotype-genotype discrepancy reveals a naturally occurring Arg93Gln substitution in the platelet beta 3 integrin that disrupts the HPA-1a epitope.
Watkins, Nicholas A.; Schaffner-Reckinger, Elisabeth; Allen, David L.; Howkins, Graham J.; Brons, Nicolaas H. C.; Smith, Graham A.; Metcalfe, Paul; Murphy, Michael F.; Kieffer, Nelly; Ouwehand, Willem H.

in Blood (2002), 99(5), 1833-9

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2001

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See detailGreen fluorescent protein (GFP) tagged to the cytoplasmic tail of alphaIIb or beta3 allows the expression of a fully functional integrin alphaIIb(beta3): effect of beta3GFP on alphaIIb(beta3) ligand binding.
Plançon, Sébastien; Morel-Kopp, M. C.; Schaffner-Reckinger, Elisabeth; Chen, P.; Kieffer, N.

in The Biochemical journal (2001), 357(Pt 2), 529-36

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1998

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See detailDistinct involvement of beta3 integrin cytoplasmic domain tyrosine residues 747 and 759 in integrin-mediated cytoskeletal assembly and phosphotyrosine signaling.
Schaffner-Reckinger, Elisabeth; Gouon, V.; Melchior, Chantal; Plançon, Sébastien; Kieffer, N.

in The Journal of biological chemistry (1998), 273(20), 12623-32

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