Publications

2017

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See detailTTCA: an R package for the identification of differentially expressed genes in time course microarray data
Albrecht, Marco; Stichel, Damian; Müller, Benedikt; Merkle, Ruth; Sticht, Carsten; Gretz, Norbert; Klingmüller, Ursula; Breuhahn, Kai; Matthäus, Franziska

in BMC Bioinformatics (2017), 18(1), 33

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See detailNeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases
Blauwendraat, Cornelis; Faghri, Faraz; Pihlstrom, Lasse; Geiger, Joshua T.; Elbaz, Alexis; Lesage, Susanne; May, Patrick; Aude, Nicolas; Abramzon, Yevgeniya; Murphy, Natalie A.; Gibbs, J. Raphael; Ryten, Mina; Ferrari, Raffaele; Bras, Jose; Guerreiro, Rita; Williams, Julie; Sims, Rebecca; Lubbe, Steven; Hernandez, Dena G.; Mok, Kin Y.; Robak, Laurie; Camphell, Roy H.; Rogaeva, Ekaterina; Traynor, Bryan J.; Chia, Ruth; Chung, Sun Ju; International Parkinson’s Disease Genomics Consortium (IPDGC); COURAGE-PD Consortium; Glaab, Enrico; Balling, Rudi; Hardy, John A.; Brice, Alexis; Houlden, Henry; Shulman, Joshua M.; Morris, Huw R.; Gasser, Thomas; Heutink, Peter; Krüger, Rejko; Sharma, Manu; Simon-Sanchez, Javier; Nalls, Mike A.; Singleton, Andrew B.; Scholz, Sonja W.

in Neurobiology of Aging (2017)

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See detailAn evaluation of real-time troposphere estimation based on GNSS Precise Point Positioning
Ding, Wenwu; Teferle, Felix Norman; Kazmierski, Kamil; Laurichesse, Denis; Yuan, Yunbin

in Journal of Geophysical Research: Atmospheres (2017), 122(5), 2779--2790

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See detailAn Evaluaton of Real-Time Troposphere Products Based on mult-GNSS Precise Point Posi)oning
Ding, Wenwu; Teferle, Felix Norman; Kazmierski, Kamil; Laurichesse, Denis; Yuan, Yunbin

Scientific Conference (2017, February 21)

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See detailParkinson’s Disease-Associated Mutant LRRK2-Mediated Inhibition of miRNA Activity is Antagonized by TRIM32
Gonzalez-Cano, Laura; Menzl, Ingeborg; Tisserand, Johan; Nicklas, Sarah; Schwamborn, Jens Christian

in Molecular Neurobiology (2017)

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See detailProblematic Gaming Behaviour in Finnish Adolescents and Young Adults: Relation to Game Genres, Gaming Motives and Self-Awareness of Problematic Use
Männikkö, N.; Billieux, Joël; Nordström, T.; Koivisto, K.; Kääriäinen, M.

in International Journal of Mental Health and Addiction (2017), 15

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See detailDerivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells
Monzel, Anna Sophia; Smits, Lisa; Hemmer, Kathrin; Hachi, Siham; Lucumi Moreno, Edinson; Van Wüllen, Thea Maria; Jarazo, Javier; Walter, Jonas; Werthschulte, Inga; Boussaad, Ibrahim; Berger, Emanuel; Fleming, Ronan MT; Bolognin, Silvia; Schwamborn, Jens Christian

in Stem Cell Reports (2017)

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See detailTumor-Initiating Cells: a criTICal review of isolation approaches and new challenges in targeting strategies
qureshi-baig, komal; Ullmann, Pit; Haan, Serge; Letellier, Elisabeth

in Molecular Cancer (2017)

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See detailExpanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations
SALA, Stefano; Van troys, Marleen; Medves, Sandrine; Catillon, Marie; Timmerman, Evy; Staes, An; Schaffner, Elisabeth; Gevaert, Kris; Ampe, Christophe

in Journal of Proteome Research (2017), doi: 10.1021/acs.jproteome.7b00034

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See detailNurr1:RXRα heterodimer activation as monotherapy for Parkinson’s disease
Spathis, Athanasios; Asvos, Xenophon; Ziavra, Despina; Karampelas, Theodoros; Topouzis, Stavros; Cournia, Zoe; Qing, Xiaobing; Alexakos, Pavlos; Smits, Lisa; Dalla, Christina; Rideout, Hardy; Schwamborn, Jens Christian; Tamvakopoulos, Constantin; Fokas, Demosthenes; Vassilatis, Demetrios

in Proceedings of the National Academy of Sciences of the United States of America (2017)

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2016

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See detailThermodynamically constrained averaging theory for cancer growth modelling
Albrecht, Marco; Sciumè, Giuseppe; Lucarelli, Philippe; Sauter, Thomas

in IFAC-PapersOnLine (2016), 49(26), 289-294

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See detailAlkyl and aryl sulfonyl p-pyridine ethanone oximes are efficient DNA photo-cleavage agents
Andreou, Nicolaos-Panagiotis; Dafnopoulos, Konstantinos; Tortopidis, Christos; Koumbis, Alexandros E.; Koffa, Maria; Psomas, George; Fylaktakidou, Konstantina C.

in Journal of Photochemistry and Photobiology B: Biology (2016), 158

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See detailThe role of HIF-1 in oncostatin M-dependent metabolic reprogramming of hepatic cells.
Battello, Nadia; Zimmer, Andreas David; Goebel, Carole; Dong, Xiangyi; Behrmann, Iris; Haan, Claude; Hiller, Karsten; Wegner, Andre

in Cancer & metabolism (2016), 4

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See detailTranscriptomic analyses of primary astrocytes under TNFα treatment
Birck, Cindy; Koncina, Eric; Heurtaux, Tony; Glaab, Enrico; Michelucci, Alessandro; Heuschling, Paul; Grandbarbe, Luc

in Genomics Data (2016), 7

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See detailProx1 is required for oligodendrocyte cell identity in adult neural stem cells of the subventricular zone
Bunk, Eva; Ertaylan, Goekhan; Ortega, Felipe; Pavlou, Maria; Gonzalez Cano, Laura; Stergiopoulos, Athanasios; Safaiyan, Shima; Voels, Sandra; van Cann, Marianne; Politis, Panagiotis; Berninger, Benedikt; del Sol Mesa, Antonio; Schwamborn, Jens Christian

in Stem Cells (2016)

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See detailSystems biology integration of proteomic data in rodent models of depression reveals involvement of the immune response and glutamatergic signalling
Carboni, Lucia; Nguyen, Thanh Phuong; Caberlotto, Laura

in PROTEOMICS – Clinical Applications (2016)

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See detailMitochondrial Defects and Neurodegeneration in Mice Overexpressing Wild Type or G399S Mutant HtrA2
Casadei, Nicolas; Sood, Poonan; Ulrich, Thomas; Kieper, Nicole; Helling, Stefan; May, Caroline; Glaab, Enrico; Chen, Jing; Nuber, Silke; Marcus, Katrin; Rapaport, Doron; Ott, Thomas; Riess, O.; Krüger, Rejko; Fitzgerald, Julia

in Human Molecular Genetics (2016), 25(3), 459-71

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See detailVariant PNPLA3 increases the HCC risk: prospective study in patients treated at the Saarland University Medical Center
Casper, Markus; Krawczyk, Marcin; Behrmann, Iris; Glanemann, Matthias; Lammert, Frank

in Zeitschrift für Gastroenterologie (2016), 54

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See detailCost-Effectiveness of Neurostimulation in Parkinson's Disease With Early Motor Complications
Dams, J; Balzer-Geldsetzer, M; Siebert, U; Deuschl, G; Schuepbach, W.M.; Krack, P; Timmermann, L; Schnitzler, A; Reese, J-P; Dodel, R; Krüger, Rejko; EARLYSTIM-investigators

in Movement Disorders : Official Journal of the Movement Disorder Society (2016), 31(8), 1183-1191

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See detail6-hydroxydopamine-induced Parkinson's disease-like degeneration generates acute micro- and astrogliosis in the nigrostriatal system but no Bioluminescence Imaging detectable alteration in adult neurogenesis
Fricke, Inga; Viel, Thomas; Worlitzer, Maik; Collmann, Franziska; Vrachimis, Alexis; Faust, Andreas; Wachsmuth, Lydia; Faber, Cornelius; Dolle, Frederic; Kuhlmann, Michael; Schaefers, Klaus; Hermann, Sven; Schwamborn, Jens Christian; Jacobs, Andreas

in European Journal of Neuroscience (2016)

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See detailInflammation Promotes a Conversion of Astrocytes into Neural Progenitor Cells via NF-κB Activation
Gabel, Sebastien; Koncina, Eric; Dorban, Gauthier; Heurtaux, Tony; Birck, Cindy; Glaab, Enrico; Michelucci, Alessandro; Heuschling, Paul; Grandbarbe, Luc

in Molecular Neurobiology (2016), 53(8), 5041-5055

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See detailOptimum stochastic modeling for GNSS tropospheric delay estimation in real-time
Hadas, Tomasz; Teferle, Felix Norman; Kazmierski, Kamil; Hordyniec, Pawel; Bosy, Jaroslaw

in GPS Solutions (2016)

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See detailProdromal Markers in Parkinson's Disease: Limitations in Longitudinal Studies and Lessons Learned.
Heinzel, S.; Roeben, B.; Ben-Shlomo, Y.; Lerche, S.; Alves, G.; Barone, P.; Behnke, S.; Berendse, H. W.; Bloem, B. R.; Burn, D.; Dodel, R.; Grosset, D. G.; Hu, M.; Kasten, M.; Krüger, Rejko; Moccia, M.; Mollenhauer, B.; Oertel, W.; Suenkel, U.; Walter, U.; Wirdefeldt, K.; Liepelt-Scarfone, I.; Maetzler, W.; Berg, D.

in Frontiers in aging neuroscience (2016), 8

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See detailUtilization of stem cells to model Parkinson's disease – current state and future challenges
Hillje, Anna-Lena; Schwamborn, Jens Christian

in Future Neurology (2016)

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See detailContext-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation.
Iwamoto, Nao; D'Alessandro, Lorenza A.; Depner, Sofia; Hahn, Bettina; Kramer, Bernhard A.; Lucarelli, Philippe; Vlasov, Artyom; Stepath, Markus; Bohm, Martin E.; Deharde, Daniela; Damm, Georg; Seehofer, Daniel; Lehmann, Wolf D.; Klingmuller, Ursula; Schilling, Marcel

in Science signaling (2016), 9(413), 13

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See detailGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Klionsky, D.; Krüger, Rejko; et al.

in Autophagy (2016), 12(1), 1-222

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See detailAdvanced stages of PD: interventional therapies and related patient-centered care
Krüger, Rejko; Hilker, Rudiger; Winkler, Christian; Lorrain, Michael; Hahne, Matthias; Redecker, Christoph; Lingor, Paul; Jost, Wolfgang H.

in Journal of neural transmission (Vienna, Austria : 1996) (2016)

See detailComputational Systems Biology: Inference and Modelling
Lecca, Paola; Ihekawaba, Adaoha; Re, Angela; Mura, Ivan; Nguyen, Thanh Phuong

Book published by Elsevier (2016)

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See detailAiming for Study Comparability in Parkinson's Disease: Proposal for a Modular Set of Biomarker Assessments to be Used in Longitudinal Studies.
Lerche, S.; Heinzel, S.; Alves, G. W.; Barone, P.; Behnke, S.; Ben-Shlomo, Y.; Berendse, H.; Bloem, B. R.; Burn, D.; Dodel, R.; Grosset, D. G.; Hipp, G.; Hu, M. T.; Kasten, M.; Krüger, Rejko; Liepelt-Scarfone, I.; Maetzler, W.; Moccia, M.; Mollenhauer, B.; Oertel, W.; Roeben, B.; Walter, U.; Wirdefeldt, K.; Berg, D.

in Frontiers in aging neuroscience (2016), 8

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See detailSOCS2: physiological and pathological functions.
Letellier, Elisabeth; Haan, Serge

in Frontiers in bioscience (Elite edition) (2016), 8

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See detailL-plastin Ser5 phosphorylation in breast cancer cells and in vitro is mediated by RSK downstream of the ERK/MAPK pathway
Lommel, Maiti; Trairatphisan, Panuwat; Gäbler, Karoline; Laurini, Christina; Muller, Arnaud; Kaoma, Tony; Vallar, Laurent; Sauter, Thomas; Schaffner, Elisabeth

in FASEB Journal (2016)

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See detailTragbare und aktiv vom Parkinson-Patienten genutzte Technologie im hauslichen Umfeld: Was bringt die Zukunft?
Maetzler, W.; Krüger, Rejko; Muller, T.; Oertel, W.; Urban, P.; Warnecke, T.; Klucken, J.

in Fortschritte der Neurologie-Psychiatrie (2016), 84 Suppl 1

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See detailDissecting functions of the N-terminal domain and GAS-site recognition in STAT3
Martincuks, Antons; Fahrenkamp, Dirk; Haan, Serge; Herrmann, Andreas; Küster, Andrea; Müller-Newen, Gerhard

in Cellular Signalling (2016), 28(8), 810-25

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See detailConstraint based modelling going multicellular
Martins Conde, Patricia; Sauter, Thomas; Pfau, Thomas

in Frontiers in Molecular Biosciences (2016), 3(3),

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See detailDownregulation of the TGF-beta pseudoreceptor BAMBI in non-small cell lung cancer enhances TGF-beta signaling and invasion.
Marwitz, Sebastian; Depner, Sofia; Dvornikov, Dmytro; Merkle, Ruth; Szczygiel, Magdalena; Muller-Decker, Karin; Lucarelli, Philippe; Wasch, Marvin; Mairbaurl, Heimo; Rabe, Klaus F.; Kugler, Christian; Vollmer, Ekkehard; Reck, Martin; Scheufele, Swetlana; Kroger, Maren; Ammerpohl, Ole; Siebert, Reiner; Goldmann, Torsten; Klingmuller, Ursula

in Cancer research (2016)

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See detailLoss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism
Meiser, Johannes; Delcambre, Sylvie; Wegner, André; Jäger, Christian; Ghelfi, Jenny; Fouquier d'Hérouël, Aymeric; Dong, Xiangyi; Weindl, Daniel; Stautner, Constantin; Nonnenmacher, Yannic; Michelucci, Alessandro; Popp, Oliver; Giesert, Florian; Schildknecht, Stefan; Kraemer, Lisa; Schneider, Jochen G.; Woitalla, Dirk; Wurst, Wolfgang; Skupin, Alexander; Vogt Weisenhorn, Daniela M.; Krüger, Rejko; Leist, Marcel; Hiller, Karsten

in Neurobiology of disease (2016), 89

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See detailA generalized gene regulatory network model of stem cell differentiation for predicting lineage specifiers
Okawa, Satoshi; Nicklas, Sarah; Zickenrott, Sascha; Schwamborn, Jens Christian; del Sol Mesa, Antonio

in Stem Cell Reports (2016)

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See detailBenchmarking procedures for high-throughput context specific reconstruction algorithms
Pacheco, Maria Irene; Pfau, Thomas; Sauter, Thomas

in Frontiers in Physiology (2016)

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See detailExpression of the Parkinson’s Disease-Associated Gene Alpha-Synuclein is Regulated by the Neuronal Cell Fate Determinant TRIM32
Pavlou, Maria; Colombo, Nicolo; Fuertes-Alvarez, Sanda; Nicklas, Sarah; Gonzalez Cano, Laura; Marin, Maria; Goncalves, Jorge; Schwamborn, Jens Christian

in Molecular Neurobiology (2016)

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See detailWhat Do We Learn from Spheroid Culture Systems? Insights from Tumorspheres Derived from Primary Colon Cancer Tissue.
Qureshi-Baig, Komal; Ullmann, Pit; Rodriguez, Fabien; frasquilho, sonia; nazarov, peter; Haan, Serge; Letellier, Elisabeth

in PLoS ONE (2016), 11

See detail“Melanomics”: analysis and integration of whole genomes, transcriptomes and miRNomes of primary melanoma patients
Reinsbach, Susanne; Wienecke, Anke; Ginolhac, Aurélien; Vallar, Laurent; Krishna; Krishna, Abhimanyu; Nazarov, Petr; May, Patrick; Kreis, Stephanie

in European Journal of Cancer (2016), 61(Suppl.1), 32

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See detailEnvironmental enrichment and physical exercise revert behavioral and electrophysiological impairments caused by reduced adult neurogenesis
Sakalem, Marna Eliana; Seidenbecher, Thomas; Zhang, Mingyue; Saffari, Roja; Kravchenko, Mykola; Wördemann, Stephanie; Diederich, Kai; Schwamborn, Jens Christian; Zhang, Weiqi; Ambrée, Oliver

in Hippocampus (2016)

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See detailCortical correlates of susceptibility to upper limb freezing in Parkinson's disease.
Scholten, M.; Govindan, R. B.; Braun, C.; Bloem, B. R.; Plewnia, C.; Krüger, Rejko; Gharabaghi, A.; Weiss, D.

in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology (2016), 127(6), 2386-93

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See detailNeuromuscular correlates of subthalamic stimulation and upper limb freezing in Parkinson's disease.
Scholten, M.; Klotz, R.; Plewnia, C.; Wachter, T.; Mielke, C.; Bloem, B. R.; Braun, C.; Ziemann, U.; Govindan, R.B.; Gharabaghi, A.; Krüger, Rejko; Weiss, D.

in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology (2016)

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See detailCyclooxygenase-2 contributes to the selective induction of cell death by the endocannabinoid 2-arachidonoyl glycerol in hepatic stellate cells.
Siegmund, S. V.; Wojtalla, A.; Schlosser, M.; Schildberg, F. A.; Knolle, P. A.; Nusing, R. M.; Zimmer, Andreas David; Strassburg, C. P.; Singer, M. V.

in Biochemical and biophysical research communications (2016), 470(3), 678-84

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See detailMulti-GNSS Benefits to Real-Time and Long-Term Monitoring Applications
Teferle, Felix Norman; Ding, Wenwu; Abraha, Kibrom Ebuy; Hunegnaw, Addisu; Laurichesse, Denis; Dach, Rolf; Kazmierski, Kamil; Yunbin, Yuan

Scientific Conference (2016, July 30)

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See detailAn Iterative Projection method for Synchronization of Invertible Matrices Over Graphs
Thunberg, Johan; Colombo, Nicolo; Yue, Zuogong; Goncalves, Jorge

in 22nd International Symposium on Mathematical Theory of Networks and Systems (2016)

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See detailA Probabilistic Boolean Network Approach for the Analysis of Cancer-Specific Signalling: A Case Study of Deregulated PDGF Signalling in GIST.
Trairatphisan, Panuwat; Wiesinger, Monique; Bahlawane, Christelle; Haan, Serge; Sauter, Thomas

in PloS one (2016), 11(5), 0156223

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See detailHypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production
Ullmann, Pit; qureshi-baig, komal; Rodriguez, Fabien; Ginolhac, Aurélien; nonnenmacher, yannic; Ternes, Dominik; Weiler, Jil; Gaebler, Karoline; bahlawane, Christelle; hiller, karsten; Haan, Serge; Letellier, Elisabeth

in Oncotarget (2016)

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See detailmiR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers
Vetter, G.; Saumet, A.; Moes, Michèle; Vallar, L.; Le Béchec, Antony; Laurini, Christina; Sabbah, M.; Arar, K.; Theillet, C.; Lecellier, C.-H.; Friederich, E.

in Oncogene (2016), 35(5), 670

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See detailAlpha-synuclein gene variants may predict neurostimulation outcome.
Weiss, D.; Herrmann, S.; Wang, Lin; Schulte, C.; Brockmann, K.; Plewnia, C.; Gasser, T.; Sharma, M.; Gharabaghi, A.; Krüger, Rejko

in Movement disorders : official journal of the Movement Disorder Society (2016)

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See detailInverse Problems for Matrix Exponential in System Identification: System Aliasing
Yue, Zuogong; Thunberg, Johan; Goncalves, Jorge

in 22nd International Symposium on Mathematical Theory of Networks and Systems (2016)

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See detailPhosphorylation of the PDH complex precedes HIF-1-mediated effects and PDK1 upregulation during the first hours of hypoxic treatment in HCC cells
Zimmer, Andreas David; Walbrecq, Geoffroy; Kozar, Ines; Behrmann, Iris; Haan, Claude

in Hypoxia (2016), 4

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2015

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See detailInsight into metabolic pathways of the potential biofuel producer, Paenibacillus polymyxa ICGEB2008
Adlakha, Nidhi; Pfau, Thomas; Ebenhöh, Oliver; Yazdani, Syed Shams

in Biotechnology for Biofuels (2015), 8(159),

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See detailGoals in Nutrition Science 2015–2020
Allison, David B.; Bassaganya-Riera, Josep; Burlingname, Barbara; Brown, Andrew W.; le Coutre, Johannes; Dickson, Suzanne L.; van Eden, Willem; Garssen, Johan; Hontecillas, Raquel; Khoo, Chor San H.; Knorr, Dietrich; Kussmann, Martin; Magistretti, Pierre J.; Mehta, Tapan; Meule, Adrian; Rychlik, Michael; Vögele, Claus

in Frontiers in Nutrition (2015), 2(26),

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See detailConstitutive activation of oncogenic PDGFRalpha-mutant proteins occurring in GIST patients induces receptor mislocalisation and alters PDGFRalpha signalling characteristics.
Bahlawane, Christelle; Eulenfeld, Rene; Wiesinger, Monique; Wang, Jiali; Muller, Arnaud; Girod, Andreas; Nazarov, Petr V.; Felsch, Kathrin; Vallar, Laurent; Sauter, Thomas; Satagopam, Venkata; Haan, Serge

in Cell Communication and Signaling (2015), 13

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See detailTRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability
Bahnassawy, Lamia’a; Perumal, Thanneer; Gonzalez Cano, Laura; Hillje, Anna-Lena; Taher, Leila; Makalowski, Wojciech; Suzuki, Yutaka; Fuellen, Georg; del Sol Mesa, Antonio; Schwamborn, Jens Christian

in Scientific Reports (2015)

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See detailCirculating microRNAs as candidate biomarkers for the surveillance of melanoma patients
Behrmann, Iris; Margue, Christiane; Kreis, Stephanie

in EBioMedicine (2015)

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See detailTRIM32 Senses and Restricts Influenza A Virus by Ubiquitination of PB1 Polymerase
Bishi; Wang, Lingyan; Ding, Hao; Schwamborn, Jens Christian; Li, Shitao; Dorf, Martin

in PLoS Pathogens (2015)

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See detailShort- and long-term outcome of chronic pallidal neurostimulation in monogenic isolated dystonia
Bruggemann, N.; Kuhn, A.; Schneider, S. A.; Kamm, C.; Wolters, A.; Krause, P.; Moro, E.; Steigerwald, F.; Wittstock, M.; Tronnier, V.; Lozano, A. M.; Hamani, C.; Poon, Y. Y.; Zittel, S.; Wachter, T.; Deuschl, G.; Krüger, Rejko; Kupsch, A.; Munchau, A.; Lohmann, K.; Volkmann, J.; Klein, C.

in Neurology (2015), 84(9), 895-903

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See detailLow-bias phosphopeptide enrichment from scarce samples using plastic antibodies
Chen, Jing; Shinde, Sudhirkumar; Koch, Markus-Hermann; Eisenacher, Martin; Galozzi, Sara; Lerari, Thilo; Barkovits, Katalin; Subedi, Prabal; Krüger, Rejko; Kuhlmann, Katja; Sellergren, Borje; Helling, Stefan; Marcus, Katrin

in Scientific reports (2015), 5

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See detailConstitutive expression of tdTomato protein as a cytotoxicity and proliferation marker for space radiation biology
Chishti, Arif A.; Hellweg, Christine E.; Berger, Thomas; Baumstark-Khan, Christa; Feles, Sebastian; Kätzel, Thorben; Reitz, Günther

in Life Sciences in Space Research (2015), 4

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See detailEffects of Endocrine Disruptor Compounds, Alone or in Combination, on Human Macrophage-Like THP-1 Cell Response
Couleau, Nicolas; Falla, Jairo; Beillerot, Adeline; Battaglia, Eric; d’Innocenzo, Marielle; Plançon, Sébastien; Laval-Gilly, Philippe; Bennasroune, Amar

in PLoS ONE (2015), 10(7), 0131428

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See detailRole of Calprotectin as a Modulator of the IL27-Mediated Proinflammatory Effect on Endothelial Cells
Dorosz, Susann Antonia; Ginolhac, Aurélien; Kähne, Thilo; Naumann, Michael; Sauter, Thomas; Salsmann, Alexandre; Bueb, Jean-Luc

in Mediators of Inflammation (2015), 2015

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See detailDo Genome-scale Models Need Exact Solvers or Clearer Standards?
Ebrahim, Ali; Almaas, Eivind; Bauer, Eugen; Bordbar, Aarash; Burgard, Anthony P.; Chang, Roger L.; Dräger, Andreas; Famili, Iman; Feist, Adam M.; Fleming, Ronan MT; Fong, Stephen S.; Hatzimanikatis, Vassily; Herrgård, Markus J.; Holder, Allen; Hucka, Michael; Hyduke, Daniel; Jamshidi, Neema; Lee, Sang Yup; Le Novère, Nicolas; Lerman, Joshua A.; Lewis, Nathan E.; Ma, Ding; Mahadevan, Radhakrishnan; Maranas, Costas; Nagarajan, Harish; Navid, Ali; Nielsen, Jens; Nielsen, Lars K.; Nogales, Juan; Noronha, Alberto; Pal, Csaba; Palsson, Bernhard O.; Papin, Jason A.; Patil, Kiran R.; Price, Nathan D.; Reed, Jennifer L.; Saunders, Michael; Senger, Ryan S.; Sonnenschein, Nikolaus; Sun, Yuekai; Thiele, Ines

in Molecular Systems Biology (2015), 11(10), 1

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See detailTripartite Containing Motif 32 Modulates Proliferation of Human Neural Precursor Cells in HIV-1 Neurodegeneration
Fatima, Mahar; Kumari, Rina; Schwamborn, Jens Christian; Mahadevan, Anita; Shankar, Susarla; Raja, R; Seth, Pankaj

in Cell Death & Differentiation (2015)

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See detailCell type-selective disease-association of genes under high regulatory load
Galhardo, Mafalda Sofia; Berninger, Philipp; Nguyen, Thanh Phuong; Sauter, Thomas; Sinkkonen, Lasse

in Nucleic Acids Research (2015), 43(18), 8839-8855

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See detailNLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in Astrocytes.
Gustin, Audrey; Kirchmeyer, Mélanie; Koncina, Eric; Felten, Paul; Losciuto, Sophie; Heurtaux, Tony; Tardivel, A; Heuschling, Paul; Dostert, Catherine

in PLoS ONE (2015), 10(6),

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See detailThe oncogenic FIP1L1-PDGFRalpha fusion protein displays skewed signaling properties compared to its wild-type PDGFRalpha counterpart.
Haan, Serge; Bahlawane, Christelle; Wang, Jiali; Nazarov, Petr V.; Muller, Arnaud; Eulenfeld, Rene; Haan, Claude; Rolvering, Catherine; Vallar, Laurent; Satagopam, Venkata; Sauter, Thomas; Wiesinger, Monique

in JAK-STAT (2015), 4(1), 1062596

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See detailDelineating the Tes Interaction Site in Zyxin and Studying Cellular Effects of Its Disruption
Hadzic, Ermin; Catillon, Marie; Halavatyi, Aliaksandr; Medves, Sandrine; Van Troys, Marleen; Moes, Michèle; Baird, Michelle A; Davidson, Michael W; Schaffner, Elisabeth; Ampe, Christophe; Friederich, Evelyne

in PLoS ONE (2015)

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See detailMiR-128 represses L1 retrotransposition by binding directly to L1 RNA
Hamdorf, Matthias; Idica, A.; Zisoulis, D. G.; Gamelin, L.; Martin, C.; Sanders, K. J.; Pedersen, I. M.

in Nature Structural and Molecular Biology (2015), 22(10), 824-831

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See detailThe neural stem cell fate determinant TRIM32 regulates complex behavioral traits
Hillje, Anna-Lena; Beckmann, Elisabeth; Pavlou, Maria Angeliki; Jäger, Christian; Pacheco, Maria Irene; Sauter, Thomas; Schwamborn, Jens Christian; Lewejohann, Lars

in Frontiers in Cellular Neuroscience (2015)

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See detailDiversity of key players in the microbial ecosystems of the human body.
Jordan, Ferenc; Lauria, Mario; Scotti, Marco; Nguyen, Thanh Phuong; Praveen, Paurush; Morine, Melissa; Priami, Corrado

in Scientific reports (2015), 5

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See detailNeural stem cells in Parkinson’s disease: a role for neurogenesis defects in onset and progression
Le Grand, Jaclyn Nicole; Gonzalez Cano, Laura; Pavlou, Maria Angeliki; Schwamborn, Jens Christian

in Cellular and Molecular Life Sciences : CMLS (2015)

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See detailInhibition of αIIbβ3 Ligand Binding by an αIIb Peptide that Clasps the Hybrid Domain to the βI Domain of β3
Lee, Wen Hwa; Schaffner, Elisabeth; Tsoukatos, Demokritos C; Aylward, Kelly; Moussis, Vassilios; Tsirakis, Vassilios; Trypou, Paraskevi; Egot, Marion; Baruch, Dominique; Kieffer, Nelly; Bachelot-Loza, Christilla

in PLoS ONE (2015)

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See detailMethods in Neuroepidemiology Characterization of European Longitudinal Cohort Studies in Parkinson's Disease - Report of the JPND Working Group BioLoC-PD
Lerche, S.; Liepelt-Scarfone, I.; Alves, G.; Barone, P.; Behnke, S.; Ben-Shlomo, Y.; Berendse, H.; Burn, D.; Dodel, R.; Grosset, D.; Heinzel, S.; Hu, M.; Kasten, M.; Krüger, Rejko; Maetzler, W.; Moccia, M.; Mollenhauer, B.; Oertel, W.; Roeben, B.; Sunkel, U.; Walter, U.; Wirdefeldt, K.; Berg, D.

in Neuroepidemiology (2015), 45(4), 282-297

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See detailHind limb unloading, a model of spaceflight conditions, leads to decreased B lymphopoiesis similar to aging
Lescale, Chloé; Schenten, Véronique; Djeghloul, Dounia; Bennabi, Meriem; Gaignier, Fanny; Vandamme, Katleen; Strazielle, Catherine; Kuzniak, Isabelle; Petite, Hervé; Dosquet, Christine; Frippiat, Jean-Pol; Goodhardt, Michèle

in FASEB Journal (2015), 29(2), 455-63

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See detailInitiation and dose optimization for levodopa-carbidopa intestinal gel: Insights from phase 3 clinical trials
Lew, M. F.; Slevin, J. T.; Krüger, Rejko; Martinez, Castrillo; Chatamra, K.; Dubow, J. S.; Robieson, W. Z.; Benesh, J. A.; Fung, V. S.

in Parkinsonism & related disorders (2015), 21(7), 742-748

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See detailDifferentiation of neuroepithelial stem cells into functional dopaminergic neurons in 3D microfluidic cell culture
Lucumi Moreno, Edinson; Hachi, Siham; Hemmer, Kathrin; Trietsch, Sebastian; Baumuratov, Aidos; Hankemeier, Thomas; Vulto, Paul; Schwamborn, Jens Christian; Fleming, Ronan MT

in Lab on a Chip - Miniaturisation for Chemistry & Biology (2015), 15

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See detailMultiscale model of dynamic neuromodulation integrating neuropeptide-induced signaling pathway activity with membrane electrophysiology.
Makadia, Hirenkumar K.; Anderson, Warren D.; Fey, Dirk; Sauter, Thomas; Schwaber, James S.; Vadigepalli, Rajanikanth

in Biophysical journal (2015), 108(1), 211-23

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See detailComparison of a healthy miRNome with melanoma patient miRNomes: are microRNAs suitable serum biomarkers for cancer?
Margue, Christiane; Reinsbach, Susanne; Philippidou, Demetra; Beaume, Nicolas; Walters, Casandra; Schneider, Jochen; Nashan, Dorothee; Behrmann, Iris; Kreis, Stephanie

in Oncotarget (2015), 6(14), 12110-27

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See detailThe NG2 Proteoglycan Protects Oligodendrocyte Precursor Cells against Oxidative Stress via Interaction with OMI/HtrA2
Maus, F.; Sakry, D.; Biname, F.; Karram, K.; Rajalingam, K.; Watts, C.; Heywood, R.; Krüger, Rejko; Stegmuller, J.; Werner, H. B.; Nave, K. A.; Kramer-Albers, E. M.; Trotter, J.

in PLoS ONE (2015), 10(9), 0137311

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See detailRegulation of Neutrophil Degranulation and Cytokine Secretion: A Novel Model Approach Based on Linear Fitting
Naegelen, Isabelle; Beaume, Nicolas; Plançon, Sébastien; Schenten, Véronique; Tschirhart, Eric; Bréchard, Sabrina

in Journal of Immunology Research (2015), 2015

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See detailNovel drug target identification for the treatment of dementia using multi-relational association mining
Nguyen, Thanh Phuong; Priami, Corrado; Caberlotto, Laura

in Scientific Reports (2015), 5

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See detailThe RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs
Nicklas, Sarah; Okawa, Satoshi; Hillje, Anna-Lena; Gonzalez Cano, Laura; del Sol Mesa, Antonio; Schwamborn, Jens Christian

in Nucleic Acids Research (2015)

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See detailThe COMT Val/Met polymorphism modulates effects of tDCS on response inhibition
Nieratschker, V.; Kiefer, C.; Giel, K.; Krüger, Rejko; Plewnia, C.

in Brain stimulation (2015), 8(2), 283-288

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See detailCollective physician perspectives on non-oral medication approaches for the management of clinically relevant unresolved issues in Parkinson's disease: Consensus from an international survey and discussion program
Odin, P.; Chaudhuri, K.R.; Slevin, J.T.; Volkmann, J.; Dietrichs, E.; Martinez-Martin, P.; Krauss, J.K.; Henriksen, T.; Katzenschlager, R.; Antonini, A.; Rascol, O.; Poewe, W.; Krüger, Rejko; National Steering Committees

in Parkinsonism & Related Disorders (2015)

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See detailTREM2 R47H variant and risk of essential tremor: a cross-sectional international multicenter study
Ortega-Cubero, S.; Lorenzo-Betancor, O.; Lorenzo, E.; Agundez, J. A.; Jimenez-Jimenez, F. J.; Ross, O. A.; Wurster, I.; Mielke, C.; Lin, J.J.; Coria, F.; Clarimon, J.; Ezquerra, M.; Brighina, L.; Annesi, G.; Alonso-Navarro, H.; Garcia-Martin, E.; Gironell, A.; Marti, M.J.; Yueh, K.C.; Wszolek, Z.K.; Sharma, M.; Berg, D.; Krüger, Rejko; Pastor, M.A.; Pastor, P.

in Parkinsonism & related disorders (2015), 21(3), 306-309

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See detailIntegrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network
Pacheco, Maria Irene; John, Elisabeth; Kaoma, Tony; Heinäniemi, Merja; Nicot, Nathalie; Vallar, Laurent; Bueb, Jean-Luc; Sinkkonen, Lasse; Sauter, Thomas

in BMC Genomics (2015), 16(809),

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See detailRapid and robust generation of long-term self-renewing human neural stem cells with the ability to generate mature astroglia
Palm, Thomas; Bolognin, Silvia; Meiser, Johannes; Nickels, Sarah Louise; Traeger, Claudia; Meilenbrock, Ralf-Leslie; Brockhaus, Johannes; Streitmueller, Miriam; Missler, Markus; Schwamborn, Jens Christian

in Scientific Reports (2015), 5

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See detailTowards improved genome-scale metabolic network reconstructions: unification, transcript specificity and beyond.
Pfau, Thomas; Pacheco, Maria Irene; Sauter, Thomas

in Briefings in bioinformatics (2015)

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See detailClinically meaningful parameters of progression and long-term outcome of Parkinson disease: An international consensus statement
Puschmann, A.; Brighina, L.; Markopoulou, K.; Aasly, J.; Chung, S. J.; Frigerio, R.; Hadjigeorgiou, G.; Koks, S.; Krüger, Rejko; Siuda, J.; Wider, C.; Zesiewicz, T. A.; Maraganore, D. M.

in Parkinsonism & related disorders (2015), 21(7), 675-682

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See detailA draft network of ligand–receptor-mediated multicellular signalling in human
Ramilowski, Jordan; Goldberg, Tatyana; Harshbarger, Jayson; Kloppman, Edda; Lizio, Marina; Satagopam, Venkata; Itoh, Masayoshi; Kawaji, Hideya; Carninci; Rost, Burkhard; Forrest, Alistair

in Nature Communications (2015), 6

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See detailComparative integrated omics: identification of key functionalities in microbial community-wide metabolic networks
Roume, Hugo; Buschart, Anna; Muller, Emilie; May, Patrick; Satagopam, Venkata; Laczny, Cédric; Narayanasamy, Shaman; Lebrun, Laura; Hoopmann, Michael; Schupp, James; Gillece, John; Hicks, Nathan; Engelthaler, David; Sauter, Thomas; Keim, Paul; Moritz, Robert; Wilmes, Paul

in Biofilms and Microbiomes (2015), 1(15007),

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See detailIL-1beta mediates MMP secretion and IL-1beta neosynthesis via upregulation of p22phox and NOX4 activity in human articular chondrocytes
Rousset, F.; Hazane-Puch, F.; Pinosa, C.; Nguyen, Minh Vu Chong; Grange, L.; Soldini, A.; Rubens-Duval, B.; Dupuy, C.; Morel, F.; Lardy, B.

in Osteoarthritis and Cartilage (2015), 23(11), 1972-1980

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See detailCK2 phosphorylation of C/EBPdelta regulates its transcription factor activity.
Schwind, Lisa; Zimmer, Andreas David; Gotz, Claudia; Montenarh, Mathias

in The international journal of biochemistry & cell biology (2015), 61

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See detailID: 194: Role of microRNAs in signal transduction pathways of the inflammatory cytokine Interleukin-6: Relevance for liver diseases
Servais, Florence; Kirchmeyer, Mélanie; Hamdorf, Matthias; Haan, Claude; Casper, Markus; Lammert, Frank; Nazarov, Petr; Vallar, Laurent; Kreis, Stephanie; Behrmann, Iris

in Cytokine (2015), 76(1), 99-

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See detailSynthesis of folate- pegylated polyester nanoparticles encapsulating ixabepilone for targeting folate receptor overexpressing breast cancer cells
Siafaka, P.; Betsiou, M.; Tsolou, A.; Angelou, E.; Agianian, B.; Koffa, Maria; Chaitidou, S.; Karavas, E.; Avgoustakis, K.; Bikiaris, D.

in Journal of Materials Science: Materials in Medicine (2015), 26(12), 1-14

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See detailA microtubule-independent role of p150glued in secretory cargo concentration at endoplasmic reticulum exit sites
Verissimo, Fatima; Halavatyi, Aliaksandr; Pepperkok, Rainer; Weiss, Matthias

in Journal of Cell Science (2015), 128(22), 4160-4170

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See detailLarge-scale assessment of polyglutamine repeat expansions in Parkinson disease
Wang, L.; Aasly, J. O.; Annesi, G.; Bardien, S.; Bozi, M.; Brice, A.; Carr, J.; Chung, S. J.; Clarke, C.; Crosiers, D.; Deutschlander, A.; Eckstein, G.; Farrer, M. J.; Goldwurm, S.; Garraux, G.; Hadjigeorgiou, G. M.; Hicks, A. A.; Hattori, N.; Klein, C.; Jeon, B.; Kim, Y. J.; Lesage, S.; Lin, J.J.; Lynch, T.; Lichtner, P.; Lang, A.E.; Mok, V.; Jasinska-Myga, B.; Mellick, G. D.; Morrison, K. E.; Opala, G.; Pihlstrom, L.; Pramstaller, P. P.; Park, S. S.; Quattrone, A.; Rogaeva, E.; Ross, O. A.; Stefanis, L.; Stockton, J. D.; Silburn, P. A.; Theuns, J.; Tan, E. K.; Tomiyama, H.; Toft, M.; Van Broeckhoven, C.; Uitti, R. J.; Wirdefeldt, K.; Wszolek, Z.; Xiromerisiou, G.; Yueh, K. C.; Zhao, Y.; Gasser, T.; Maraganore, D. M.; Krüger, Rejko; Sharma, M.

in Neurology (2015), 85(15), 1283-92

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See detailSubthalamic stimulation modulates cortical motor network activity and synchronization in Parkinson's disease
Weiss, D.; Klotz, R.; Govindan, R. B.; Scholten, M.; Naros, G.; Ramos-Murguialday, A.; Bunjes, F.; Meisner, C.; Plewnia, C.; Krüger, Rejko; Gharabaghi, A.

in Brain : a journal of neurology (2015), 138(Pt 3), 679-93

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See detailLong-term outcome of deep brain stimulation in fragile X-associated tremor/ataxia syndrome
Weiss, D.; Mielke, C.; Wachter, T.; Bender, B.; Liscic, R. M.; Scholten, M.; Naros, G.; Plewnia, C.; Gharabaghi, A.; Krüger, Rejko

in Parkinsonism & related disorders (2015), 21(3), 310-313

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2014

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See detailMitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1.
Burbulla, L. F.; Fitzgerald, J. C.; Stegen, K.; Westermeier, J.; Thost, A.-K.; Kato, H.; Mokranjac, D.; Sauerwald, J.; Martins, Luisa; Woitalla, D.; Rapaport, D.; Riess, O.; Proikas-Cezanne, T.; Rasse, T. M.; Krüger, Rejko

in Cell death & disease (2014), 5

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See detailOverexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice.
Casadei, Nicolas; Pohler, Anne-Maria; Tomas-Zapico, Cristina; Torres-Peraza, Jesus; Schwedhelm, Ivo; Witz, Annemarie; Zamolo, Irina; De Heer, Raymond; Spruijt, Berry; Noldus, Lucas P. J. J.; Klucken, Jochen; Lucas, Jose J.; Kahle, Philipp J.; Krüger, Rejko; Riess, Olaf; Nuber, Silke

in Human molecular genetics (2014), 23(3), 767-81

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See detailAlpha-synuclein repeat variants and survival in Parkinson's disease.
Chung, Sun Ju; Biernacka, Joanna M.; Armasu, Sebastian M.; Anderson, Kari; Frigerio, Roberta; Aasly, Jan O.; Annesi, Grazia; Bentivoglio, Anna Rita; Brighina, Laura; Chartier-Harlin, Marie-Christine; Goldwurm, Stefano; Hadjigeorgiou, Georgios; Jasinska-Myga, Barbara; Jeon, Beom Seok; Kim, Yun Joong; Krüger, Rejko; Lesage, Suzanne; Markopoulou, Katerina; Mellick, George; Morrison, Karen E.; Puschmann, Andreas; Tan, Eng-King; Crosiers, David; Theuns, Jessie; Van Broeckhoven, Christine; Wirdefeldt, Karin; Wszolek, Zbigniew K.; Elbaz, Alexis; Maraganore, Demetrius M.

in Movement disorders : official journal of the Movement Disorder Society (2014)

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See detailA mathematical model of metabolism and regulation provides a systems-level view of how Escherichia coli responds to oxygen
Ederer, M; Steinsiek, S; Stagge, S; Rolfe, MD; Ter Beek, A; Knies, D; Teixeira de Mattos, MJ; Sauter, Thomas; Green, J; Poole, RK; Bettenbrock, K; Sawodny, O

in Frontiers in Microbiology (2014), 5(124),

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See detailGene regulatory network analysis reveals differences in site-specific cell fate determination in mammalian brain
Ertaylan, Gökhan; Okawa, Satoshi; Schwamborn, Jens Christian; del Sol Mesa, Antonio

in Frontiers in Cellular Neuroscience (2014)

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See detailChIP-seq profiling of the active chromatin marker H3K4me3 and PPARγ, CEBPα and LXR target genes in human SGBS adipocytes
Galhardo, Mafalda Sofia; Sinkkonen, Lasse; Berninger, Philipp; Lin, Jake; Sauter, Thomas; Heinäniemi, Merja

in Genomics Data (2014), 2

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See detailTranscriptomics profiling of human SGBS adipogenesis
Galhardo, Mafalda Sofia; Sinkkonen, Lasse; Berninger, Philipp; Lin, Jake; Sauter, Thomas; Heinäniemi, Merja

in Genomics Data (2014), 2

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See detailMolecular cloning and expression analysis of Pleurodeles waltl complement component C3 under normal physiological conditions and environmental stresses
Gueguinou, Nathan; Huin-Schohn, Cécile; Ouzren-Zarhloul, Nassima; Ghislin, Stéphanie; Frippiat, Jean-Pol

in Developmental and Comparative Immunology (2014), 46(2), 180-185

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See detailOrigin-Dependent Neural Cell Identities in Differentiated Human iPSCs In Vitro and after Transplantation into the Mouse Brain
Hargus, Gunnar; Ehrlicher, Marc; Arauzo-Bravo, Marcos; Hemmer, Kathrin; Hallmann, Anna-Lena; Reinhardt, Peter; Kee-Pyo, Kim; Adachi, Kenjiro; Santourlidis; Ghanjati, Foued; Fauser, Mareike; Ossig, Christiana; Storch; Kim, Jeong Beom; Schwamborn, Jens Christian; Sterneckert, Jared; Schoeler, Hans; Kuhlmann, Tanja; Zaehres, Holm

in Cell Reports (2014)

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See detailProtective effect of LRRK2 p.R1398H on risk of Parkinson's disease is independent of MAPT and SNCA variants.
Heckman, Michael G.; Elbaz, Alexis; Soto-Ortolaza, Alexandra I.; Serie, Daniel J.; Aasly, Jan O.; Annesi, Grazia; Auburger, Georg; Bacon, Justin A.; Boczarska-Jedynak, Magdalena; Bozi, Maria; Brighina, Laura; Chartier-Harlin, Marie-Christine; Dardiotis, Efthimios; Destee, Alain; Ferrarese, Carlo; Ferraris, Alessandro; Fiske, Brian; Gispert, Suzana; Hadjigeorgiou, Georgios M.; Hattori, Nobutaka; Ioannidis, John P. A.; Jasinska-Myga, Barbara; Jeon, Beom S.; Kim, Yun Joong; Klein, Christine; Krüger, Rejko; Kyratzi, Elli; Lin, Chin-Hsien; Lohmann, Katja; Loriot, Marie-Anne; Lynch, Timothy; Mellick, George D.; Mutez, Eugenie; Opala, Grzegorz; Park, Sung Sup; Petrucci, Simona; Quattrone, Aldo; Sharma, Manu; Silburn, Peter A.; Sohn, Young Ho; Stefanis, Leonidas; Tadic, Vera; Tomiyama, Hiroyuki; Uitti, Ryan J.; Valente, Enza Maria; Vassilatis, Demetrios K.; Vilarino-Guell, Carles; White, Linda R.; Wirdefeldt, Karin; Wszolek, Zbigniew K.; Wu, Ruey-Meei; Xiromerisiou, Georgia; Maraganore, Demetrius M.; Farrer, Matthew J.; Ross, Owen A.

in Neurobiology of aging (2014), 35(1), 2665-14

See detailKapitel 34: Mediatoren
Heinrich, Peter C.; Haan, Serge; Hermanns, Heike M.; Müller-Newen, Gerhard; Schaper, Fred

in Heinrich, Peter C.; Müller, Matthias; Graeve, Lutz (Eds.) Biochemie und Pathobiochemie (2014)

See detailKapitel 35: Rezeptoren und ihre Signaltransduktion
Heinrich, Peter C.; Haan, Serge; Hermanns, Heike M.; Müller-Newen, Gerhard; Schaper, Fred

in Heinrich, Peter C.; Müller, Matthias; Graeve, Lutz (Eds.) Biochemie und Pathobiochemie (2014)

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See detailInduced Neural Stem Cells Achieve Long-Term Survival and Functional Integration in the Adult Mouse Brain
Hemmer, Kathrin; Zhang, Mingyue; van Wuellen, Thea; Sakalem, Marna; Tapia, Natalia; Baumuratov, Aidos; Kaltschmidt, Christian; Kaltschmidt, Barbara; Schoeler, Hans R.; Zhang, Weiqi; Schwamborn, Jens Christian

in Stem Cell Reports (2014)

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See detailBasic Regulatory Principles of Escherichia coli's Electron Transport Chain for Varying Oxygen Conditions.
Henkel, Sebastian G.; Beek, Alexander Ter; Steinsiek, Sonja; Stagge, Stefan; Bettenbrock, Katja; de Mattos, M. Joost Teixeira; Sauter, Thomas; Sawodny, Oliver; Ederer, Michael

in PloS one (2014), 9(9), 107640

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See detailEIF4G1 is neither a strong nor a common risk factor for Parkinson's disease: evidence from large European cohorts
Huttenlocher, Johanna; Krüger, Rejko; Capetian, Philipp; Lohmann, Katja; Brockmann, Kathrin; Csoti, Ilona; Klein, Christine; Berg, Daniela; Gasser, Thomas; Bonin, Michael; Riess, Olaf; Bauer, Peter

in Journal of medical genetics (2014), 0

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See detailComparison of beamformers for EEG source signal reconstruction
Jonmohamadi, Yaqub; Poudel; Innes, Carrie; Weiss, Daniel; Krüger, Rejko; Jones, Richard

in Biomedical Signal Processing and Control (2014), 14

See detailDynamic change of host gastrointestinal microbiome and immune status in relation to mucosal barrier effects during chemotherapy and immune ablative intervention in humans
Kaysen, Anne; Heintz-Buschart, Anna; Lebrun, Laura; Graf, Norbert; Simon, Arne; Bittenbring, Jörg; Kreis, Stephanie; Schneider, Jochen; Wilmes, Paul

Poster (2014, April)

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See detailIdentification of New IkappaBalpha Complexes by an Iterative Experimental and Mathematical Modeling Approach.
Konrath, Fabian; Witt, Johannes; Sauter, Thomas; Kulms, Dagmar

in PLoS computational biology (2014), 10(3), 1003528

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See detailMMP13 mutations are the cause of recessive metaphyseal dysplasia, Spahr type
Le Béchec, Antony; Bonafe, Luisa; Liang, Jinlong; Gorna, Maria W.; Zhang, Qingyan; Ha-Vinh, Russia; Campos-Xavier, Ana Belinda; Unger, Sheila; Beckmann, Jacques S.; Stevenson, Brian; Giedion, Andres; Liu, Xuanzhu; Superti-Furga, Giulio; Wang, Wei; Spahr, André; Superti-Furga, Andrea

in American Journal of Medical Genetics, Part A (2014), 164(5), 1175-1179

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See detailIdentification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer.
Letellier, Elisabeth; Schmitz, Martine; Baig, Komal; Beaume, Nicolas; Schwartz, C.; Frasquilho, S.; Antunes, L.; Marcon, N.; Nazarov, P. V.; Vallar, L.; Even, J.; Haan, Serge

in British journal of cancer (2014), 111(4), 726-35

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See detailCombinatorial regulation of lipoprotein lipase by microRNAs during mouse adipogenesis
Liivrand, Maria; Heinäniemi, Merja; John, Elisabeth; Schneider, Jochen; Sauter, Thomas; Sinkkonen, Lasse

in RNA Biology (2014), 11(1), 76-91

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See detailDecoding the dynamics of cellular metabolism and the action of 3-bromopyruvate and 2-deoxyglucose using pulsed stable isotope-resolved metabolomics
Mudrich Epouse Dorosz, Susann Antonia; Pietzke, Matthias; Zasada, Christin

in Cancer & Metabolism (2014)

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See detailAn essential role of syntaxin 3 protein for granule exocytosis and secretion of IL-1α, IL-1β, IL-12b, and CCL4 from differentiated HL-60 cells
Naegelen, Isabelle; Plançon, Sébastien; Nicot, Nathalie; Kaoma, Tony; Muller, Arnaud; Vallar, Laurent; Tschirhart, Eric; Bréchard, Sabrina

in Journal of Leukocyte Biology (2014), 97

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See detailMolecular role of TRIM32 in stem cell fate specification
Nicklas, Sarah Maria

Doctoral thesis (2014)

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See detailFrom genome-wide association studies to next-generation sequencing: lessons from the past and planning for the future.
Sharma, Manu; Krüger, Rejko; Gasser, Thomas

in JAMA neurology (2014), 71(1), 5-6

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See detailMutant COQ2 in multiple-system atrophy.
Sharma, Manu; Wenning, Gregor; Krüger, Rejko

in The New England journal of medicine (2014), 371(1), 80-1

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See detailWater Chemistry and Hydrometeorology in a Glacierized Catchment in the Polar Urals, Russia
STACHNIK, Łukasz1; WAŁACH, Piotr; UZAROWICZ, Łukasz; YDE, Jacob; Tosheva, Zornitza; WROŃSKA-WAŁACH, Dominika

in Journal of Mountain Science (2014), 11(5), 1097-1111

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See detailGlobal investigation and meta-analysis of the C9orf72 (G4C2)n repeat in Parkinson disease.
Theuns, Jessie; Verstraeten, Aline; Sleegers, Kristel; Wauters, Eline; Gijselinck, Ilse; Smolders, Stefanie; Crosiers, David; Corsmit, Ellen; Elinck, Ellen; Sharma, Manu; Krüger, Rejko; Lesage, Suzanne; Brice, Alexis; Chung, Sun Ju; Kim, Mi-Jung; Kim, Young Jin; Ross, Owen A.; Wszolek, Zbigniew K.; Rogaeva, Ekaterina; Xi, Zhengrui; Lang, Anthony E.; Klein, Christine; Weissbach, Anne; Mellick, George D.; Silburn, Peter A.; Hadjigeorgiou, Georgios M.; Dardiotis, Efthimios; Hattori, Nobutaka; Ogaki, Kotaro; Tan, Eng-King; Zhao, Yi; Aasly, Jan; Valente, Enza Maria; Petrucci, Simona; Annesi, Grazia; Quattrone, Aldo; Ferrarese, Carlo; Brighina, Laura; Deutschlander, Angela; Puschmann, Andreas; Nilsson, Christer; Garraux, Gaetan; LeDoux, Mark S.; Pfeiffer, Ronald F.; Boczarska-Jedynak, Magdalena; Opala, Grzegorz; Maraganore, Demetrius M.; Engelborghs, Sebastiaan; De Deyn, Peter Paul; Cras, Patrick; Cruts, Marc; Van Broeckhoven, Christine

in Neurology (2014)

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See detailoptPBN: An Optimisation Toolbox for Probabilistic Boolean Networks
Trairatphisan, Panuwat; Mizera, Andrzej; Pang, Jun; Tantar, Alexandru-Adrian; Sauter, Thomas

in PLoS ONE (2014), 9(7), 980011-15

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See detailFast reconstruction of compact context-specific metabolic network models
Vlassis, Nikos; Pacheco, Maria Irene; Sauter, Thomas

in PLoS Computational Biology (2014), 10(1), 1003424

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See detailThe subthalamic nucleus modulates the early phase of probabilistic classification learning.
Weiss, Daniel; Lam, Judith M.; Breit, Sorin; Gharabaghi, Alireza; Krüger, Rejko; Luft, Andreas R.; Wachter, Tobias

in Experimental brain research (2014), 232(7), 2255-62

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2013

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See detailNuevas estrategias farmacológicas en el tratamiento de la psoriasis
Andres Ejarque, Rosa Maria

Doctoral thesis (2013)

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See detailThe Parkinson's Disease-Associated LRRK2 Mutation R1441G Inhibits Neuronal Differentiation of Neural Stem Cells.
Bahnassawy, Lamia A; Nicklas, Sarah; Palm, Thomas; Menzl, Ingeborg; Birzele, Fabian; Gillardon, Frank; Schwamborn, Jens Christian

in Stem Cells & Development (2013)

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See detailTocopherol derivative TFA-12 promotes myelin repair in experimental models of multiple sclerosis.
Blanchard, Benoit; Heurtaux, Tony; Nait Oumesmar, Brahim

in Journal of Neuroscience (2013), 33(28), 11633-42

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See detailNew Insights into the Regulation of Neutrophil NADPH Oxidase Activity in the Phagosome: A Focus on the Role of Lipid and Ca(2+) Signaling
Bréchard, Sabrina; Plançon, Sébastien; Tschirhart, Eric

in Antioxidants & Redox Signaling (2013), 18(6), 661-676

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See detailOn different aspects of network analysis in systems biology
Chaiboonchoe, Amphun; Jurkowski, Wiktor; Pellet, Johann; Glaab, Enrico; Kolodkin, Alexey; Raussel, Antonio; Le Béchec, Antony; Ballereau, Stéphane; Meyniel, Laurene; Crespo, Isaac; Ahmed, Hassan; Volpert, Vitaly; Lotteau, Vincent; Baliga, Nitin; Hood, Leroy; Sol, Antonio del; Balling, Rudi; Auffray, Charles

in Systems Biology (2013), 1

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See detailPredicting missing expression values in gene regulatory networks using a discrete logic modeling optimization guided by network stable states
Crespo, Isaac; Krishna, Abhimanyu; Le Béchec, Antony; del Sol Mesa, Antonio; *Co-first-authors

in Nucleic Acids Research (2013), 41(1), 8

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See detailInnate and adaptive effects of inflammasomes on T cell responses
Dostert, Catherine; Ludigs, Kristina; Guarda, Greta

in Current Opinion in Immunology (2013), 25(3), 359-365

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See detailThe recruitment of p47 and Rac2G12V at the phagosome is transient and phosphatidylserine dependent.
Faure, Marie Cecile; Sulpice, Jean-Claude; Delattre, Maud; Lavielle, Marc; Prigent, Magali; Cuif, Marie-Helene; Melchior, Chantal; Tschirhart, Eric; Nusse, Oliver; Dupre-Crochet, Sophie

in Biology of the Cell (2013)

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See detailJAK2 mutants (e.g., JAK2V617F) and their importance as drug targets in myeloproliferative neoplasms
Gäbler, Karoline; Behrmann, Iris; Haan, Claude

in JAK-STAT (2013), 2(3), 25025

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See detailCooperative effects of Janus and Aurora kinase inhibition by CEP701 in cells expressing Jak2V617F
Gäbler, Karoline; Rolvering, Catherine; Kaczor, Jakub; Eulenfeld, R.; Méndez, S. A.; Berchem, G.; Palissot, V.; Behrmann, Iris; Haan, Claude

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in PloS one (2013), 8(12), 83714

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Sharma, Manu; Ioannidis, John P. A.; Aasly, Jan O.; Annesi, Grazia; Brice, Alexis; Bertram, Lars; Bozi, Maria; Barcikowska, Maria; Crosiers, David; Clarke, Carl E.; Facheris, Maurizio F.; Farrer, Matthew; Garraux, Gaetan; Gispert, Suzana; Auburger, Georg; Vilarino-Guell, Carles; Hadjigeorgiou, Georgios M.; Hicks, Andrew A.; Hattori, Nobutaka; Jeon, Beom S.; Jamrozik, Zygmunt; Krygowska-Wajs, Anna; Lesage, Suzanne; Lill, Christina M.; Lin, Juei-Jueng; Lynch, Timothy; Lichtner, Peter; Lang, Anthony E.; Libioulle, Cecile; Murata, Miho; Mok, Vincent; Jasinska-Myga, Barbara; Mellick, George D.; Morrison, Karen E.; Meitnger, Thomas; Zimprich, Alexander; Opala, Grzegorz; Pramstaller, Peter P.; Pichler, Irene; Park, Sung Sup; Quattrone, Aldo; Rogaeva, Ekaterina; Ross, Owen A.; Stefanis, Leonidas; Stockton, Joanne D.; Satake, Wataru; Silburn, Peter A.; Strom, Tim M.; Theuns, Jessie; Tan, Eng-King; Toda, Tatsushi; Tomiyama, Hiroyuki; Uitti, Ryan J.; Van Broeckhoven, Christine; Wirdefeldt, Karin; Wszolek, Zbigniew; Xiromerisiou, Georgia; Yomono, Harumi S.; Yueh, Kuo-Chu; Zhao, Yi; Gasser, Thomas; Maraganore, Demetrius; Krüger, Rejko

in Journal of medical genetics (2012), 49(11), 721-6

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See detailLarge-scale replication and heterogeneity in Parkinson disease genetic loci.
Sharma, Manu; Ioannidis, John P. A.; Aasly, Jan O.; Annesi, Grazia; Brice, Alexis; Van Broeckhoven, Christine; Bertram, Lars; Bozi, Maria; Crosiers, David; Clarke, Carl; Facheris, Maurizio; Farrer, Matthew; Garraux, Gaetan; Gispert, Suzana; Auburger, Georg; Vilarino-Guell, Carles; Hadjigeorgiou, Georgios M.; Hicks, Andrew A.; Hattori, Nobutaka; Jeon, Beom; Lesage, Suzanne; Lill, Christina M.; Lin, Juei-Jueng; Lynch, Timothy; Lichtner, Peter; Lang, Anthony E.; Mok, Vincent; Jasinska-Myga, Barbara; Mellick, George D.; Morrison, Karen E.; Opala, Grzegorz; Pramstaller, Peter P.; Pichler, Irene; Park, Sung Sup; Quattrone, Aldo; Rogaeva, Ekaterina; Ross, Owen A.; Stefanis, Leonidas; Stockton, Joanne D.; Satake, Wataru; Silburn, Peter A.; Theuns, Jessie; Tan, Eng-King; Toda, Tatsushi; Tomiyama, Hiroyuki; Uitti, Ryan J.; Wirdefeldt, Karin; Wszolek, Zbigniew; Xiromerisiou, Georgia; Yueh, Kuo-Chu; Zhao, Yi; Gasser, Thomas; Maraganore, Demetrius; Krüger, Rejko

in Neurology (2012), 79(7), 659-67

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See detailLRRK2: Understanding the role of common and rare variants in Parkinson's disease.
Sharma, Manu; Krüger, Rejko; Gasser, Thomas

in Movement disorders : official journal of the Movement Disorder Society (2012), 27(4), 475

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See detailJAM-C is an apical surface marker for neural stem cells.
Stelzer, Sandra; Worlitzer, Maik M. A.; Bahnassawy, Lamia A; Hemmer, Kathrin; Rugani, Kirite; Werthschulte, Inga; Schon, Anna-Lena; Brinkmann, Benjamin F.; Bunk, Eva C.; Palm, Thomas; Ebnet, Klaus; Schwamborn, Jens Christian

in Stem Cells & Development (2012), 21(5), 757-66

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See detailDynamics and feedback loops in the transforming growth factor beta signaling pathway.
Wegner, Katja; Bachmann, Anastasia; Schad, Jan-Ulrich; Lucarelli, Philippe; Sahle, Sven; Nickel, Peter; Meyer, Christoph; Klingmuller, Ursula; Dooley, Steven; Kummer, Ursula

in Biophysical chemistry (2012), 162

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See detailSubthalamic nucleus stimulation restores the efferent cortical drive to muscle in parallel to functional motor improvement.
Weiss, Daniel; Breit, Sorin; Hoppe, Julia; Hauser, Ann-Kathrin; Freudenstein, Dirk; Krüger, Rejko; Sauseng, Paul; Govindan, Rathinaswamy B.; Gerloff, Christian

in The European journal of neuroscience (2012), 35(6), 896-908

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See detailLong-term follow-up of subthalamic nucleus stimulation in glucocerebrosidase-associated Parkinson's disease.
Weiss, Daniel; Brockmann, Kathrin; Srulijes, Karin; Meisner, Christoph; Klotz, Rosa; Reinbold, Sophia; Hauser, Ann-Kathrin; Schulte, Claudia; Berg, Daniela; Gasser, Thomas; Plewnia, Christian; Gharabaghi, Alireza; Breit, Sorin; Wachter, Tobias; Krüger, Rejko

in Journal of neurology (2012), 259(9), 1970-2

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See detailInduced pluripotent stem cells generated from adult bone marrow-derived cells of the nonhuman primate (Callithrix jacchus) using a novel quad-cistronic and excisable lentiviral vector.
Wiedemann, Anastasia; Hemmer, Kathrin; Bernemann, Inga; Gohring, Gudrun; Pogozhykh, Olena; Figueiredo, Constanca; Glage, Silke; Schambach, Axel; Schwamborn, Jens Christian; Blasczyk, Rainer; Muller, Thomas

in Cellular reprogramming (2012), 14(6), 485-96

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See detailAnalysing the role of UVB-induced translational inhibition and PP2Ac deactivation in NF-kappaB signalling using a minimal mathematical model.
Witt, Johannes; Konrath, Fabian; Sawodny, Oliver; Ederer, Michael; Kulms, Dagmar; Sauter, Thomas

in PLoS ONE (2012), 7(7), 40274

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See detailAnti-inflammatory treatment induced regenerative oligodendrogenesis in parkinsonian mice.
Worlitzer, Maik Ma; Bunk, Eva C.; Hemmer, Kathrin; Schwamborn, Jens Christian

in Stem cell research & therapy (2012), 3(4), 33

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See detailProbabilistic model checking of the PDGF signaling pathway
Yuan, Qixia; Trairatphisan, Panuwat; Pang, Jun; Mauw, Sjouke; Wiesinger, Monique; Sauter, Thomas

in Transactions on Computational Systems Biology (2012), XIV

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2011

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See detailEffects of subthalamic nucleus stimulation on emotional prosody comprehension in Parkinson's disease.
Bruck, Carolin; Wildgruber, Dirk; Kreifelts, Benjamin; Krüger, Rejko; Wachter, Tobias

in PloS one (2011), 6(4), 19140

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See detailCellular organization of adult neurogenesis in the Common Marmoset.
Bunk, Eva C.; Stelzer, Sandra; Hermann, Sven; Schafers, Michael; Schlatt, Stefan; Schwamborn, Jens Christian

in Aging Cell (2011), 10(1), 28-38

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See detailConverging environmental and genetic pathways in the pathogenesis of Parkinson's disease.
Burbulla, Lena F.; Krüger, Rejko

in Journal of the neurological sciences (2011), 306(1-2), 1-8

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See detailIndependent and joint effects of the MAPT and SNCA genes in Parkinson disease.
Elbaz, Alexis; Ross, Owen A.; Ioannidis, John P. A.; Soto-Ortolaza, Alexandra I.; Moisan, Frederic; Aasly, Jan; Annesi, Grazia; Bozi, Maria; Brighina, Laura; Chartier-Harlin, Marie-Christine; Destee, Alain; Ferrarese, Carlo; Ferraris, Alessandro; Gibson, J. Mark; Gispert, Suzana; Hadjigeorgiou, Georgios M.; Jasinska-Myga, Barbara; Klein, Christine; Krüger, Rejko; Lambert, Jean-Charles; Lohmann, Katja; van de Loo, Simone; Loriot, Marie-Anne; Lynch, Timothy; Mellick, George D.; Mutez, Eugenie; Nilsson, Christer; Opala, Grzegorz; Puschmann, Andreas; Quattrone, Aldo; Sharma, Manu; Silburn, Peter A.; Stefanis, Leonidas; Uitti, Ryan J.; Valente, Enza Maria; Vilarino-Guell, Carles; Wirdefeldt, Karin; Wszolek, Zbigniew K.; Xiromerisiou, Georgia; Maraganore, Demetrius M.; Farrer, Matthew J.

in Annals of neurology (2011), 69(5), 778-92

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See detailDesigning logical rules to model the response of biomolecular networks with complex interactions: an application to cancer modeling.
Guziolowski, Carito; Blachon, Sylvain; Baumuratova, Tatiana; Stoll, Gautier; Radulescu, Ovidiu; Siegel, Anne

in IEEE/ACM Transactions on Computational Biology and Bioinformatics (2011), 8(5), 1223-34

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See detailJak1 has a dominant role over Jak3 in signal transduction through γc-containing cytokine receptors
Haan, Claude; Rolvering, Catherine; Raulf, F.; Kapp, M.; Drückes, P.; Thoma, G.; Behrmann, Iris; Zerwes, H.-G.

in Chemistry & Biology (2011), 18(3), 314-323

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See detailA systems biology approach to analyse leaf carbohydrate metabolism in Arabidopsis thaliana.
Henkel, Sebastian; Nagele, Thomas; Hormiller, Imke; Sauter, Thomas; Sawodny, Oliver; Ederer, Michael; Heyer, Arnd G.

in EURASIP Journal on Bioinformatics & Systems Biology (2011), 2011(1), 2

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See detailNeural stem cells maintain their stemness through protein kinase C zeta-mediated inhibition of TRIM32.
Hillje, Anna-Lena; Worlitzer, Maik M. A.; Palm, Thomas; Schwamborn, Jens Christian

in Stem Cells (2011), 29(9), 1437-47

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See detailPPARγ population shift produces disease-related changes in molecular networks associated with metabolic syndrome
Jurkowski, Wiktor; Roomp, Kirsten; Crespo, Isaac; Schneider, Jochen; del Sol Mesa, Antonio

in Cell Death & Disease (2011), 2(8), 192

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See detailThe E3-ubiquitin ligase TRIM2 regulates neuronal polarization.
Khazaei, Mohammad R.; Bunk, Eva C.; Hillje, Anna-Lena; Jahn, Hannah M.; Riegler, Eva M.; Knoblich, Jurgen A.; Young, Peter; Schwamborn, Jens Christian

in Journal of Neurochemistry (2011), 117(1), 29-37

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See detailA large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease.
Krüger, Rejko; Sharma, Manu; Riess, Olaf; Gasser, Thomas; Van Broeckhoven, Christine; Theuns, Jessie; Aasly, Jan; Annesi, Grazia; Bentivoglio, Anna Rita; Brice, Alexis; Djarmati, Ana; Elbaz, Alexis; Farrer, Matthew; Ferrarese, Carlo; Gibson, J. Mark; Hadjigeorgiou, Georgios M.; Hattori, Nobutaka; Ioannidis, John P. A.; Jasinska-Myga, Barbara; Klein, Christine; Lambert, Jean-Charles; Lesage, Suzanne; Lin, Juei-Jueng; Lynch, Timothy; Mellick, George D.; de Nigris, Francesa; Opala, Grzegorz; Prigione, Alessandro; Quattrone, Aldo; Ross, Owen A.; Satake, Wataru; Silburn, Peter A.; Tan, Eng King; Toda, Tatsushi; Tomiyama, Hiroyuki; Wirdefeldt, Karin; Wszolek, Zbigniew; Xiromerisiou, Georgia; Maraganore, Demetrius M.

in Neurobiology of aging (2011), 32(3), 5489-18

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See detailOlfactory neuron-specific expression of A30P alpha-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages.
Nuber, Silke; Petrasch-Parwez, Elisabeth; Arias-Carrion, Oscar; Koch, Leanie; Kohl, Zacharias; Schneider, Jacqueline; Calaminus, Carsten; Dermietzel, Rolf; Samarina, Anna; Boy, Jana; Nguyen, Huu P.; Teismann, Peter; Velavan, Thirumalaisamy Palanichamy; Kahle, Philipp J.; von Horsten, Stephan; Fendt, Markus; Krüger, Rejko; Riess, Olaf

in Neurobiology of disease (2011), 44(2), 192-204

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See detailAssociation of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study.
Ross, Owen A.; Soto-Ortolaza, Alexandra I.; Heckman, Michael G.; Aasly, Jan O.; Abahuni, Nadine; Annesi, Grazia; Bacon, Justin A.; Bardien, Soraya; Bozi, Maria; Brice, Alexis; Brighina, Laura; Van Broeckhoven, Christine; Carr, Jonathan; Chartier-Harlin, Marie-Christine; Dardiotis, Efthimios; Dickson, Dennis W.; Diehl, Nancy N.; Elbaz, Alexis; Ferrarese, Carlo; Ferraris, Alessandro; Fiske, Brian; Gibson, J. Mark; Gibson, Rachel; Hadjigeorgiou, Georgios M.; Hattori, Nobutaka; Ioannidis, John P. A.; Jasinska-Myga, Barbara; Jeon, Beom S.; Kim, Yun Joong; Klein, Christine; Krüger, Rejko; Kyratzi, Elli; Lesage, Suzanne; Lin, Chin-Hsien; Lynch, Timothy; Maraganore, Demetrius M.; Mellick, George D.; Mutez, Eugenie; Nilsson, Christer; Opala, Grzegorz; Park, Sung Sup; Puschmann, Andreas; Quattrone, Aldo; Sharma, Manu; Silburn, Peter A.; Sohn, Young Ho; Stefanis, Leonidas; Tadic, Vera; Theuns, Jessie; Tomiyama, Hiroyuki; Uitti, Ryan J.; Valente, Enza Maria; van de Loo, Simone; Vassilatis, Demetrios K.; Vilarino-Guell, Carles; White, Linda R.; Wirdefeldt, Karin; Wszolek, Zbigniew K.; Wu, Ruey-Meei; Farrer, Matthew J.

in Lancet neurology (2011), 10(10), 898-908

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See detailSuppression of extrapyramidal side effects of doxepin by thalamic deep brain stimulation for Tourette syndrome.
Rzesnitzek, L.; Wachter, T.; Krüger, Rejko; Gharabaghi, A.; Plewnia, C.

in Neurology (2011), 77(18), 1708-9

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See detailSphingosine kinases regulate NOX2 activity via p38 MAPK-dependent translocation of S100A8/A9
Schenten, Véronique; Melchior, Chantal; Steinckwich, Nathalie; Tschirhart, Eric; Bréchard, Sabrina

in Journal of Leukocyte Biology (2011), 89(4), 587-596

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See detailRole of sepiapterin reductase gene at the PARK3 locus in Parkinson's disease.
Sharma, Manu; Maraganore, Demetrius M.; Ioannidis, John P. A.; Riess, Olaf; Aasly, Jan O.; Annesi, Grazia; Abahuni, Nadine; Bentivoglio, Anna Rita; Brice, Alexis; Van Broeckhoven, Christine; Chartier-Harlin, Marie-Christine; Destee, Alain; Djarmati, Ana; Elbaz, Alexis; Farrer, Matthew; Ferrarese, Carlo; Gibson, J. Mark; Gispert, Suzana; Hattori, Nobutaka; Jasinska-Myga, Barbara; Klein, Christine; Lesage, Suzanne; Lynch, Timothy; Lichtner, Peter; Lambert, Jean-Charles; Lang, Anthony E.; Mellick, George D.; De Nigris, Francesa; Opala, Grzegorz; Quattrone, Aldo; Riva, Chiara; Rogaeva, Ekaterina; Ross, Owen A.; Satake, Wataru; Silburn, Peter A.; Theuns, Jessie; Toda, Tatsushi; Tomiyama, Hiroyuki; Uitti, Ryan J.; Wirdefeldt, Karin; Wszolek, Zbigniew; Gasser, Thomas; Krüger, Rejko

in Neurobiology of aging (2011), 32(11), 21081-5

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See detailAn essential role of STIM1, Orai1, and S100A8-A9 proteins for Ca2+ signaling and FcγR-mediated phagosomal oxidative activity
Steinckwich, Natacha; Schenten, Véronique; Melchior, Chantal; Bréchard, Sabrina; Tschirhart, Eric

in Journal of Immunology (2011), 186(4), 2182-2191

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See detailSlowly progressive Parkinson syndrome due to thalamic butterfly astrocytoma.
Wachter, T.; Engeholm, M.; Bisdas, S.; Schittenhelm, J.; Gasser, T.; Krüger, Rejko

in Neurology (2011), 77(4), 404-5

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See detailRapid emergence of temporal and pulvinar lesions in MELAS mimicking Creutzfeldt-Jakob disease.
Weiss, D.; Brockmann, K.; Nagele, T.; Gasser, T.; Krüger, Rejko

in Neurology (2011), 77(9), 914

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See detailCombined stimulation of the substantia nigra pars reticulata and the subthalamic nucleus is effective in hypokinetic gait disturbance in Parkinson's disease.
Weiss, Daniel; Breit, Sorin; Wachter, Tobias; Plewnia, Christian; Gharabaghi, Alireza; Krüger, Rejko

in Journal of neurology (2011), 258(6), 1183-5

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See detailCentral oscillators in a patient with neuropathic tremor: evidence from intraoperative local field potential recordings.
Weiss, Daniel; Govindan, Rathinaswamy B.; Rilk, Albrecht; Wachter, Tobias; Breit, Sorin; Zizlsperger, Leopold; Haarmeier, Thomas; Plewnia, Christian; Krüger, Rejko; Gharabaghi, Alireza

in Movement disorders : official journal of the Movement Disorder Society (2011), 26(2), 323-7

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See detailCombined STN/SNr-DBS for the treatment of refractory gait disturbances in Parkinson's disease: study protocol for a randomized controlled trial.
Weiss, Daniel; Wachter, Tobias; Meisner, Christoph; Fritz, Melanie; Gharabaghi, Alireza; Plewnia, Christian; Breit, Sorin; Krüger, Rejko

in Trials (2011), 12

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See detailModeling time delay in the NFkappaB signaling pathway following low dose IL-1 stimulation.
Witt, Johannes; Barisic, Sandra; Sawodny, Oliver; Ederer, Michael; Kulms, Dagmar; Sauter, Thomas

in EURASIP Journal on Bioinformatics & Systems Biology (2011), 2011(1), 3

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See detailA study of the PDGF signaling pathway with PRISM
Yuan, Qixia; Pang, Jun; Mauw, Sjouke; Trairatphisan, Panuwat; Wiesinger, Monique; Sauter, Thomas

in Proceedings of the 3rd Workshop on Computational Models for Cell Processes (2011), EPTCS 67

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2010

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See detailQuantitative kinetic study of the actin-bundling protein L-plastin and of its impact on actin turn-over.
Al Tanoury, Ziad; Schaffner-Reckinger, Elisabeth; Halavatyi, Aliaksandr; Hoffmann, Celine; Moes, Michèle; Hadzic, Ermin; Catillon, Marie; Yatskou, Mikalai; Friederich, Evelyne

in PloS one (2010), 5(2), 9210

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See detailLocalizing potentially active post-transcriptional regulations in the Ewing's sarcoma gene regulatory network.
Baumuratova, Tatiana; Surdez, Didier; Delyon, Bernard; Stoll, Gautier; Delattre, Olivier; Radulescu, Ovidiu; Siegel, Anne

in BMC Systems Biology (2010), 4

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See detailEffective long-term subthalamic stimulation in PARK8 positive Parkinson's disease.
Breit, Sorin; Wachter, T.; Schmid-Bielenberg, D.; Weiss, D.; Leitner, P.; Nagele, T.; Freudenstein, D.; Gasser, T.; Krüger, Rejko

in Journal of neurology (2010), 257(7), 1205-7

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See detailBalance is the challenge--the impact of mitochondrial dynamics in Parkinson's disease.
Burbulla, Lena F.; Krebiehl, Guido; Krüger, Rejko

in European journal of clinical investigation (2010), 40(11), 1048-60

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See detailDissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis.
Burbulla, Lena F.; Schelling, Carina; Kato, Hiroki; Rapaport, Doron; Woitalla, Dirk; Schiesling, Carola; Schulte, Claudia; Sharma, Manu; Illig, Thomas; Bauer, Peter; Jung, Stephan; Nordheim, Alfred; Schols, Ludger; Riess, Olaf; Krüger, Rejko

in Human molecular genetics (2010), 19(22), 4437-52

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See detailDiseases as network perturbations
del Sol Mesa, Antonio; Balling, Rudi; Hood, Leroy; Galas, David J.

in Current Opinion in Biotechnology (2010), 21(4), 566-571

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See detailAn alpaca single-domain antibody blocks filopodia formation by obstructing L-plastin-mediated F-actin bundling.
Delanote, Veerle; Vanloo, Berlinda; Catillon, Marie; Friederich, Evelyne; Vandekerckhove, Joel; Gettemans, Jan

in FASEB Journal (2010), 24(1), 105-18

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See detailFunctions of hepatitis C virus non-structural protein 2
Dentzer, Thomas

Doctoral thesis (2010)

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See detailSignal transduction, receptors, mediators and genes: Younger than ever - The 13th meeting of the Signal Transduction Society focused on aging and immunology
Entschladen, F.; Altschmied, J.; Baumgrass, R.; Behrmann, Iris; Giehl, K.; Hermanns, H.; Huber, O.; Kieser, A.; Klotz, L.-O.; Kubatzky, K. F.; Hass, R.; Janssen, O.; Friedrich, K.

in Cell Communication and Signaling (2010), 8

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See detailPerspectives for the use of structural information and chemical genetics to develop inhibitors of Janus kinases.
Haan, Claude; Behrmann, Iris; Haan, Serge

in Journal of Cellular & Molecular Medicine (2010), 14(3), 504-27

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See detailA mathematical model of actin filament turnover for fitting FRAP data
Halavatyi, A. A.; Nazarov, P. V.; Al Tanoury, Z.; Apanasovich, V. V.; Yatskou, M.; Friederich, Evelyne

in European Biophysics Journal [=EBJ] (2010), 39(4), 669-677

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See detailNew biological investigations on 3-bromophenyl 6-acetoxymethyl-2-oxo-2H-1-benzopyran-3-carboxylate as anti-angiogenic agent
Hemmer, Marc; Kempen, Isabelle; de Tullio, Pascal; Frankenne, Francis; Lambert, Vincent; Blacher, Silvia; Bueb, Jean-Luc; Foidart, Jean-Michel; Noël, Agnès; Tschirhart, Eric; Pirotte, Bernard

in Drug Development Research (2010), 71

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See detailMicroglial activation depends on beta-amyloid conformation: role of the formylpeptide receptor 2
Heurtaux, Tony; Michelucci, Alessandro; Losciuto, Sophie; Gallotti, Christian; Felten, Paul; Dorban, Gauthier; Grandbarbe, Luc; Morga, Eleonora; Heuschling, Paul

in Journal of Neurochemistry (2010), 114(2), 576-586

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See detailThe actin filament cross-linker L-plastin confers resistance to TNF-alpha in MCF-7 breast cancer cells in a phosphorylation-dependent manner.
Janji, Bassam; Vallar, Laurent; Al Tanoury, Ziad; Bernardin, Francois; Vetter, Guillaume; Schaffner-Reckinger, Elisabeth; Berchem, Guy; Friederich, Evelyne; Chouaib, Salem

in Journal of Cellular & Molecular Medicine (2010), 14(6A), 1264-75

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See detailModulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1.
Kieper, Nicole; Holmstrom, Kira M.; Ciceri, Dalila; Fiesel, Fabienne C.; Wolburg, Hartwig; Ziviani, Elena; Whitworth, Alexander J.; Martins, Luisa; Kahle, Philipp J.; Krüger, Rejko

in Experimental cell research (2010), 316(7), 1213-24

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See detailReduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1.
Krebiehl, Guido; Ruckerbauer, Sabine; Burbulla, Lena F.; Kieper, Nicole; Maurer, Brigitte; Waak, Jens; Wolburg, Hartwig; Gizatullina, Zemfira; Gellerich, Frank N.; Woitalla, Dirk; Riess, Olaf; Kahle, Philipp J.; Proikas-Cezanne, Tassula; Krüger, Rejko

in PloS one (2010), 5(2), 9367

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See detailTime-Resolved Expression Profiling of the Nuclear Receptor Superfamily in Human Adipogenesis
Lahnalampi, Mari; Heinäniemi, Merja; Sinkkonen, Lasse; Wabitsch, Martin; Carlberg, Carsten

in PLoS ONE (2010), 5(9),

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See detailMathematical modeling of the central carbohydrate metabolism in Arabidopsis reveals a substantial regulatory influence of vacuolar invertase on whole plant carbon metabolism.
Nagele, Thomas; Henkel, Sebastian; Hormiller, Imke; Sauter, Thomas; Sawodny, Oliver; Ederer, Michael; Heyer, Arnd G.

in Plant Physiology (2010), 153(1), 260-72

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See detailTransgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in mice.
Nuber, Silke; Franck, Thomas; Wolburg, Hartwig; Schumann, Ulrike; Casadei, Nicolas; Fischer, Kristina; Calaminus, Carsten; Pichler, Bernd J.; Chanarat, Sittinan; Teismann, Peter; Schulz, Jorg B.; Luft, Andreas R.; Tomiuk, Jurgen; Wilbertz, Johannes; Bornemann, Antje; Krüger, Rejko; Riess, Olaf

in Neurogenetics (2010), 11(1), 107-20

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See detailBrain tumor stem cells.
Palm, Thomas; Schwamborn, Jens Christian

in Biological Chemistry (2010), 391(6), 607-17

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See detailSignatures of MicroRNAs and selected MicroRNA target genes in human melanoma
Philippidou, Demetra; Schmitt, Martina; Moser, D. A; Margue, Christiane; Nazarov, P. V. B; Muller, A. B; Vallar, L. B; Nashan, D. C; Behrmann, Iris; Kreis, Stephanie

in Cancer Research (2010), 70(10), 4163-4173

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See detailPsychological preparation and postoperative outcomes for adults undergoing surgery under general anaesthesia (Protocol)
Powell, Rachael; Bruce, Julie; Johnston, Marie; Vögele, Claus; Scott, Neil; Shemar, Manjee; Roberts, Tracey

in Cochrane Database of Systematic Reviews (Online) (2010), (8), 1-15

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See detailCross-regulation of cytokine signalling: Pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradation
Radtke, S.; Wüller, S.; Yang, X.-P.; Lippok, B. E.; Mütze, B.; Mais, C.; Schmitz-Van De Leur, H.; Bode, J. G.; Gaestel, M.; Heinrich, P. C.; Behrmann, Iris; Schaper, F. A; Hermanns, H. M.

in Journal of Cell Science (2010), 123(6), 947-959

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See detailiPLA 2 , a novel determinant in Ca2+ - and phosphorylation-dependent S100A8/A9 regulated NOX2 activity
Schenten, Véronique; Bréchard, Sabrina; Plançon, Sébastien; Melchior, Chantal; Frippiat, Jean-Pol; Tschirhart, Eric

in Biochimica et Biophysica Acta-Molecular Cell Research (2010), 1803(7), 840-847

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See detailInterleukin-27 acts on hepatic stellate cells and induces signal transducer and activator of transcription 1-dependent responses.
Schoenherr, Caroline; Weiskirchen, Ralf; Haan, Serge

in Cell Communication and Signaling (2010), 8

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See detailFirst appraisal of brain pathology owing to A30P mutant alpha-synuclein.
Seidel, Kay; Schols, Ludger; Nuber, Silke; Petrasch-Parwez, Elisabeth; Gierga, Kristin; Wszolek, Zbigniew; Dickson, Dennis; Gai, Wei P.; Bornemann, Antje; Riess, Olaf; Rami, Abdelhaq; Den Dunnen, Wilfried F. A.; Deller, Thomas; Rub, Udo; Krüger, Rejko

in Annals of neurology (2010), 67(5), 684-9

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See detailPeriphilin is a novel interactor of synphilin-1, a protein implicated in Parkinson's disease.
Soehn, Anne S.; Franck, Thomas; Biskup, Saskia; Giaime, Emilie; Melle, Christian; Rott, Ruth; Cebo, Daniel; Kalbacher, Hubert; Ott, Erwin; Pahnke, Jens; Meitinger, Thomas; Krüger, Rejko; Gasser, Thomas; Berg, Daniela; von Eggeling, Ferdinand; Engelender, Simone; da Costa, Cristine Alves; Riess, Olaf

in Neurogenetics (2010), 11(2), 203-15

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See detailJAM-A is a novel surface marker for NG2-Glia in the adult mouse brain.
Stelzer, Sandra; Ebnet, Klaus; Schwamborn, Jens Christian

in BMC Neuroscience (2010), 11

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See detailComplex hyperkinetic movement disorders associated with POLG mutations.
Synofzik, Matthis; Schule, Rebecca; Schulte, Claudia; Krüger, Rejko; Lindig, Tobias; Schols, Ludger; Asmus, Friedrich

in Movement disorders : official journal of the Movement Disorder Society (2010), 25(14), 2472-5

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Synofzik, Matthis; Weiss, Daniel; Erharhaghen, Jite; Krüger, Rejko; Schols, Ludger

in Journal of neurology (2010), 257(10), 1751-3

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Vollmer, Stefan; Haan, Claude; Behrmann, Iris

in Biochemical Pharmacology (2010), 80(12), 2066-2073

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See detailInvoluntary eyelid closure after STN-DBS: evidence for different pathophysiological entities.
Weiss, Daniel; Wachter, Tobias; Breit, Sorin; Jacob, Simon N.; Pomper, Jorn K.; Asmus, Friedrich; Valls-Sole, Josep; Plewnia, Christian; Gasser, Thomas; Gharabaghi, Alireza; Krüger, Rejko

in Journal of neurology, neurosurgery, and psychiatry (2010), 81(9), 1002-7

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2009

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See detailSpaceflight-associated changes in immunoglobulin VH gene expression in the amphibian Pleurodeles waltl
Bascove, Matthieu; Huin-Schohn, Cécile; Gueguinou, Nathan; Tschirhart, Eric; Frippiat, Jean-Pol

in FASEB Journal (2009), 23(5), 1607-1615

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See detailInterleukin-27 displays interferon-gamma-like functions in human hepatoma cells and hepatocytes.
Bender, Herdis; Wiesinger, Monique; Nordhoff, Carolin; Schoenherr, Caroline; Haan, Claude; Ludwig, Stephan; Weiskirchen, Ralf; Kato, Nobuyuki; Heinrich, Peter C.; Haan, Serge

in Hepatology (Baltimore, Md.) (2009), 50(2), 585-91

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See detailSTIM1 but not STIM2 is an essential regulator of Ca2+ influx-mediated NADPH oxidase activity in neutrophil-like HL-60 cells
Bréchard, Sabrina; Plançon, Sébastien; Melchior, Chantal; Tschirhart, Eric

in Biochemical Pharmacology (2009), 78(5), 504-513

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See detailOAG induces an additional PKC-, PI3K-, and Rac2-mediated signaling pathway up-regulating NOX2 activity, independently of Ca 2+ entry
Bréchard, Sabrina; Salsmann, Alexandre; Tschirhart, Eric

in Journal of Leukocyte Biology (2009), 85(4), 638-647

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See detailEffective thalamic deep brain stimulation for neuropathic tremor in a patient with severe demyelinating neuropathy.
Breit, S.; Wachter, T.; Schols, L.; Gasser, T.; Nagele, T.; Freudenstein, D.; Krüger, Rejko

in Journal of neurology, neurosurgery, and psychiatry (2009), 80(2), 235-6

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Bueb, Jean-Luc

in Landry, Yves; Gies, Jean-Pierre (Eds.) Pharmacologie. Des cibles vers l’indication thérapeutique (2009)

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See detailMethyl side-chain dynamics prediction based on protein structure
Carbonell, P.; del Sol Mesa, Antonio

in Bioinformatics (2009), 25(19), 2552-8

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See detailEnergetic determinants of protein binding specificity: insights into protein interaction networks
Carbonell, P.; Nussinov, R.; del Sol Mesa, Antonio

in Proteomics (2009), 9(7), 1744-53

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See detailResidues crucial for maintaining short paths in network communication mediate signaling in proteins
del Sol Mesa, Antonio; Fujihashi, Hirotomo; Amoros, Dolors; Nussinov, Ruth

in Molecular Systems Biology (2009), 2

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del Sol Mesa, Antonio; Tsai, Chung-Jung; Ma, Buyong; Nussinov, Ruth

in Structure (2009), 17(8), 1042-1050

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See detailSingle-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinson's disease gene.
Elstner, Matthias; Morris, Christopher M.; Heim, Katharina; Lichtner, Peter; Bender, Andreas; Mehta, Divya; Schulte, Claudia; Sharma, Manu; Hudson, Gavin; Goldwurm, Stefano; Giovanetti, Alessandro; Zeviani, Massimo; Burn, David J.; McKeith, Ian G.; Perry, Robert H.; Jaros, E.; Krüger, Rejko; Wichmann, H.-Erich; Schreiber, Stefan; Campbell, Harry; Wilson, James F.; Wright, Alan F.; Dunlop, Malcolm; Pistis, Giorgio; Toniolo, Daniela; Chinnery, Patrick F.; Gasser, Thomas; Klopstock, Thomas; Meitinger, Thomas; Prokisch, Holger; Turnbull, Douglass M.

in Annals of neurology (2009), 66(6), 792-8

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Friedrich, Karlheinz; Behrmann, Iris

in Biochemie und Molekularbiologie des Menschen (2009)

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See detailCould spaceflight-associated immune system weakening preclude the expansion of human presence beyond Earth’s orbit?
Gueguinou, Nathan; Huin-Schohn, Cécile; Bascove, Matthieu; Bueb, Jean-Luc; Tschirhart, Eric; Legrand-Frossi, Christine; Frippiat, Jean-Pol

in Journal of Leukocyte Biology (2009), 86(5), 1027-1038

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See detailAn unusual insertion in Jak2 is crucial for kinase activity and differentially affects cytokine responses
Haan, Claude; Kroy, Daniela C.; Wüller, Stefan; Sommer, Ulrike; Nöcker, Tanja; Rolvering, Catherine; Behrmann, Iris; Heinrich, Peter C.; Haan, Serge

in Journal of Immunology (2009), 182(5), 2969-2977

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See detailSOCS-mediated downregulation of mutant Jak2 (V617F, T875N and K539L) counteracts cytokine-independent signaling.
Haan, Serge; Wuller, S.; Kaczor, Jakub; Rolvering, Catherine; Nocker, T.; Behrmann, Iris; Haan, Claude

in Oncogene (2009), 28(34), 3069-80

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See detailAn integrative simulation model linking major biochemical reactions of actin-polymerization to structural properties of actin filaments
Halavatyi, A. A.; Nazarov, P. V.; Medves, S.; van Troys, M.; Ampe, C.; Yatskou, M.; Friederich, Evelyne

in Biophysical Chemistry (2009), 140(1-3), 24-34

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in Journal of Neuroimmunology (2009), 210(1-2), 3-12

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See detailTranscriptional repression of microRNA genes by PML-RARA increases expression of key cancer proteins in acute promyelocytic leukemia.
Saumet, Anne; Vetter, Guillaume; Bouttier, Manuella; Portales-Casamar, Elodie; Wasserman, Wyeth W.; Maurin, Thomas; Mari, Bernard; Barbry, Pascal; Vallar, Laurent; Friederich, Evelyne; Arar, Khalil; Cassinat, Bruno; Chomienne, Christine; Lecellier, Charles-Henri

in Blood (2009), 113(2), 412-21

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See detailOverexpression of the partially activated alpha(IIb)beta3D723H integrin salt bridge mutant downregulates RhoA activity and induces microtubule-dependent proplatelet-like extensions in Chinese hamster ovary cells
Schaffner-Reckinger, Elisabeth; Salsmann, Alexandre; Debili, Najet; Bellis, Julien; De Mey, Jan; Vainchenker, William; Ouwehand, Willem H.; Kieffer, Nelly

in Journal of Thrombosis and Haemostasis [=JTH] (2009), 7(7), 1207-1217

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See detailAnalysis of an apoptotic core model focused on experimental design using artificial data.
Schlatter, R.; Conzelmann, H.; Gilles, E. D.; Sawodny, O.; Sauter, Thomas

in IET Systems Biology (2009), 3(4), 255-65

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Schlatter, Rebekka; Schmich, Kathrin; Avalos Vizcarra, Ima; Scheurich, Peter; Sauter, Thomas; Borner, Christoph; Ederer, Michael; Merfort, Irmgard; Sawodny, Oliver

in PLoS Computational Biology (2009), 5(12), 1000595

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See detailThe stimulation of dendrite growth by Sema3A requires integrin engagement and focal adhesion kinase.
Schlomann, Uwe; Schwamborn, Jens Christian; Muller, Myriam; Fassler, Reinhard; Puschel, Andreas W.

in Journal of Cell Science (2009), 122(Pt 12), 2034-42

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See detailThe TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors.
Schwamborn, Jens Christian; Berezikov, Eugene; Knoblich, Juergen A.

in Cell (2009), 136(5), 913-25

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See detailFurther delineation of the association signal on chromosome 5 from the first whole genome association study in Parkinson's disease.
Sharma, Manu; Lichtner, Peter; Krüger, Rejko; Berg, Daniela; Schulte, Claudia; Illig, Thomas; Riess, Olaf; Gasser, Thomas

in Neurobiology of aging (2009), 30(10), 1706-9

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See detailGenome-wide association study reveals genetic risk underlying Parkinson's disease.
Simon-Sanchez, Javier; Schulte, Claudia; Bras, Jose M.; Sharma, Manu; Gibbs, J. Raphael; Berg, Daniela; Paisan-Ruiz, Coro; Lichtner, Peter; Scholz, Sonja W.; Hernandez, Dena G.; Krüger, Rejko; Federoff, Monica; Klein, Christine; Goate, Alison; Perlmutter, Joel; Bonin, Michael; Nalls, Michael A.; Illig, Thomas; Gieger, Christian; Houlden, Henry; Steffens, Michael; Okun, Michael S.; Racette, Brad A.; Cookson, Mark R.; Foote, Kelly D.; Fernandez, Hubert H.; Traynor, Bryan J.; Schreiber, Stefan; Arepalli, Sampath; Zonozi, Ryan; Gwinn, Katrina; van der Brug, Marcel; Lopez, Grisel; Chanock, Stephen J.; Schatzkin, Arthur; Park, Yikyung; Hollenbeck, Albert; Gao, Jianjun; Huang, Xuemei; Wood, Nick W.; Lorenz, Delia; Deuschl, Gunther; Chen, Honglei; Riess, Olaf; Hardy, John A.; Singleton, Andrew B.; Gasser, Thomas

in Nature genetics (2009), 41(12), 1308-12

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See detailProtein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms
Tsai, C. J.; del Sol Mesa, Antonio; Nussinov, R.

in Molecular Biosystems (2009), 5(3), 207-16

See detailLes peptides opioïdes et autres médiateurs de la nociception
Tschirhart, Eric

in Landry, Yves; Gies, Jean-Pierre (Eds.) Pharmacologie. Des cibles vers l’indication thérapeutique (2009)

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See detailTime-resolved analysis of transcriptional events during SNAI1-triggered epithelial to mesenchymal transition
Vetter, G.; Le Béchec, Antony; Muller, J.; Muller, A.; Moes, Michèle; Yatskou, M.; Al Tanoury, Z.; Poch, O.; Vallar, L.; Friederich, Evelyne

in Biochemical and Biophysical Research Communications (2009), 385(4), 485-91

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See detailHypoxia-inducible factor 1alpha is up-regulated by oncostatin M and participates in oncostatin M signaling
Vollmer, Stefan; Kappler, Valérie; Kaczor, Jakub; Flügel, Daniela; Rolvering, Catherine; Kato, Nobuyuki; Kietzmann, Thomas; Behrmann, Iris; Haan, Claude

in Hepatology (Baltimore, Md.) (2009), 2009(3),

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See detailSevere muscular fasciculations as an uncommon side-effect due to microdefect of an extension wire in deep brain stimulation.
Wachter, Tobias; Weiss, Daniel; Breit, Sorin; Gasser, Thomas; Krüger, Rejko; Gharabaghi, Alireza

in Movement disorders : official journal of the Movement Disorder Society (2009), 24(14), 2161-2

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See detailIndibulin, a Novel Microtubule Inhibitor, Discriminates between Mature Neuronal and Nonneuronal Tubulin
Wienecke, Anke; Bacher, Gerald

in Cancer Research (2009), 69(1), 171-177

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See detailDevelopment of an IL-6 inhibitor based on the functional analysis of murine IL-6Ralpha(1).
Wiesinger, Monique; Haan, Serge; Wuller, Stefan; Kauffmann, Maria-Elisabeth; Recker, Tobias; Kuster, Andrea; Heinrich, Peter C.; Muller-Newen, Gerhard

in Chemistry & Biology (2009), 16(7), 783-94

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See detailMechanism of PP2A-mediated IKK beta dephosphorylation: a systems biological approach.
Witt, Johannes; Barisic, Sandra; Schumann, Eva; Allgower, Frank; Sawodny, Oliver; Sauter, Thomas; Kulms, Dagmar

in BMC Systems Biology (2009), 3

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2008

See detailCell passaging rapidly affects expression, secretion and activity of MMP9 as well as mobility of HL60 leukemia cells
Bernard, Yohann; Plançon, Sébastien; Melchior, Chantal; Tschirhart, Eric; Bueb, Jean-Luc

in Journal of Cell and Animal Biology (2008), 2(9), 160-165

See detailMicroarray expression analysis reveals genetic pathways implicated in C621 synphilin-1-mediated toxicity.
Bonin, M.; Marx, F. P.; Kautzmann, S.; Riess, O.; Krüger, Rejko

in Journal of neural transmission (Vienna, Austria : 1996) (2008), 115(7), 941-58

See detailStore-operated Ca2+ channels formed by TRPC1, TRPC6 and Orai1 and non-store-operated channels formed by TRPC3 are involved in the regulation of NADPH oxidase in HL-60 granulocytes
Bréchard, Sabrina; Melchior, Chantal; Plançon, Sébastien; Schenten, Véronique; Tschirhart, Eric

in Cell Calcium (2008)

See detailRegulation of superoxide production in neutrophils: role of calcium influx
Bréchard, Sabrina; Tschirhart, Eric

in Journal of Leukocyte Biology (2008), 84(5), 1223-1237

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See detailAnalyse der evolutiven Adaptation am Beispiel einer pyruvat-auxotrophen Escherichia coli-Mutante
Feuer, Ronny; Ederer, Michael; Gilles, Ernst Dieter; Sprenger, Georg; Sawodny, Oliver; Sauter, Thomas

in Automatisierungstechnik (2008), 56

See detailIn colon carcinogenesis, the cytoskeletal protein gelsolin is down-regulated during the transition from adenoma to carcinoma.
Gay, Fabien; Estornes, Yann; Saurin, Jean-Christophe; Joly-Pharaboz, Marie-Odile; Friederich, Evelyne; Scoazec, Jean-Yves; Abello, Jacques

in Human pathology (2008), 39(10), 1420-30

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See detailA nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the αIIbβ3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia
Ghevaert, Cedric; Salsmann, Alexandre; Watkins, Nicholas A.; Schaffner-Reckinger, Elisabeth; Rankin, Angela; Garner, Stephen F.; Stephens, Jonathan; Smith, Graham A.; Debili, Najet; Vainchenker, William; de Groot, Philip G.; Huntington, James A.; Laffan, Mike; Kieffer, Nelly; Ouwehand, Willem H.

in Blood (2008), 111(7), 3407-3414

See detailDual role of the Jak1 FERM and kinase domains in cytokine receptor binding and in stimulation-dependent Jak activation
Haan, Serge; Margue, Christiane; Engrand, A.; Rolvering, Catherine; Schmitz-Van de Leur, H.; Heinrich, P. C.; Behrmann, Iris; Haan, Claude

in Journal of Immunology (2008), 180(2), 998-1007

See detailNovel ATP1A3 mutation in a sporadic RDP patient with minimal benefit from deep brain stimulation.
Kamm, C.; Fogel, W.; Wachter, T.; Schweitzer, K.; Berg, D.; Krüger, Rejko; Freudenstein, D.; Gasser, T.

in Neurology (2008), 70(16 Pt 2), 1501-3

See detailCell density dependent increase of constitutive signal transducers and activators of transcription 3 activity in melanoma cells is mediated by Janus kinases
Kreis, Stephanie; Munz, G. A.; Haan, Serge; Heinrich, P. C.; Behrmann, Iris

in Molecular Cancer Research (2008), 5(12), 1331-41

See detailIL-24: a classic cytokine and/or a potential cure for cancer?
Kreis, Stephanie; Philippidou, Demetra; Margue, Christiane; Behrmann, Iris

in Journal of Cellular & Molecular Medicine (2008)

See detailSustained improvement of obsessive-compulsive disorder by deep brain stimulation in a woman with residual schizophrenia.
Plewnia, Christian; Schober, Franziska; Rilk, Albrecht; Buchkremer, Gerhard; Reimold, Matthias; Wachter, Tobias; Breit, Sorin; Weiss, Daniel; Krüger, Rejko; Freudenstein, Dirk

in The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) (2008), 11(8), 1181-3

See detailMitochondrial protein quality control by the proteasome involves ubiquitination and the protease Omi.
Radke, Susanne; Chander, Harish; Schafer, Patrick; Meiss, Gregor; Krüger, Rejko; Schulz, Jorg B.; Germain, Doris

in The Journal of biological chemistry (2008), 283(19), 12681-5

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See detailThe talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges.
Rodius, Sophie; Chaloin, Olivier; Moes, Michèle; Schaffner-Reckinger, Elisabeth; Landrieu, Isabelle; Lippens, Guy; Lin, Minghui; Zhang, Jie; Kieffer, Nelly

in The Journal of biological chemistry (2008), 283(35), 24212-23

See detailCa2+-dependent regulation of NOX2 activity via MRP proteins in HL-60 granulocytes
Schenten, Véronique; Bréchard, Sabrina; Melchior, Chantal; Plançon, Sébastien; Salsmann, Alexandre; Tschirhart, Eric

in Calcium Binding Proteins (2008), 3(1), 25-30

See detailReview: Familial Parkinson's disease--genetics, clinical phenotype and neuropathology in relation to the common sporadic form of the disease.
Schiesling, Carola; Kieper, Nicole; Seidel, Kay; Krüger, Rejko

in Neuropathology and applied neurobiology (2008), 34(3), 255-71

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See detailLIS1 and spindle orientation in neuroepithelial cells.
Schwamborn, Jens Christian; Knoblich, Juergen A.

in Cell Stem Cell (2008), 2(3), 193-4

See detailVertebral artery dissection presenting with ispilateral acute C5 and C6 sensorimotor radiculopathy: A case report.
Tabatabai, Ghazaleh; Schober, Wolfgang; Ernemann, Ulrike; Weller, Michael; Krüger, Rejko

in Cases journal (2008), 1(1), 139

See detailA comprehensive genetic study of the proteasomal subunit S6 ATPase in German Parkinson's disease patients.
Wahl, Claudia; Kautzmann, Sabine; Krebiehl, Guido; Strauss, Karsten; Woitalla, Dirk; Muller, Thomas; Bauer, Peter; Riess, Olaf; Krüger, Rejko

in Journal of neural transmission (Vienna, Austria : 1996) (2008), 115(8), 1141-8

See detailAdvanced spot quality analysis in two-colour microarray experiments
Yatskou, M.; Novikov, E.; Vetter, G.; Muller, A.; Barillot, E.; Vallar, L.; Friederich, Evelyne

in BMC Research Notes (2008), 1

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2007

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See detailMitochondrial translation initiation factor 3 gene polymorphism associated with Parkinson's disease.
Abahuni, Nadine; Gispert, Suzana; Bauer, Peter; Riess, Olaf; Krüger, Rejko; Becker, Tim; Auburger, Georg

in Neuroscience letters (2007), 414(2), 126-9

See detailCorrelation between growth rates, EIIACrr phosphorylation, and intracellular cyclic AMP levels in Escherichia coli K-12.
Bettenbrock, Katja; Sauter, Thomas; Jahreis, Knut; Kremling, Andreas; Lengeler, Joseph W.; Gilles, Ernst-Dieter

in Journal of Bacteriology (2007), 189(19), 6891-900

See detailLoss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin.
Exner, Nicole; Treske, Bettina; Paquet, Dominik; Holmstrom, Kira; Schiesling, Carola; Gispert, Suzana; Carballo-Carbajal, Iria; Berg, Daniela; Hoepken, Hans-Hermann; Gasser, Thomas; Krüger, Rejko; Winklhofer, Konstanze F.; Vogel, Frank; Reichert, Andreas S.; Auburger, Georg; Kahle, Philipp J.; Schmid, Bettina; Haass, Christian

in The Journal of neuroscience : the official journal of the Society for Neuroscience (2007), 27(45), 12413-8

See detailMethods for analysis of evolutive adaptation of E. coli
Feuer, Ronny; Ederer, Michael; Trachtmann, Natalie; Sauter, Thomas; Gilles, Ernst Dieter; Sprenger, Georg; Sawodny, Oliver

in Proceedings of the SICE Annual Conference, September 17-20, 2007 Kagawa University, Takamatsu City, Japan (2007)

See detailSpecial issue: Integrated approaches to cytoskeleton research
Friederich, Evelyne

in Biochimica et Biophysica Acta-Molecular Cell Research (2007), 1773(5), 603

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See detailNotch signaling modulates the activation of microglial cells
Grandbarbe, Luc; Michelucci, Alessandro; Heurtaux, Tony; Hemmer, Karin; Morga, Eleonora; Heuschling, Paul

in Glia (2007), 55(15), 1519-30

See detailA cost effective non-commercial ECL-solution for Western blot detections yielding strong signals and low background
Haan, Claude; Behrmann, Iris

in Journal of Immunological Methods (2007), 318(1-2), 11-9

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See detailDual bioactivity of resveratrol fatty alcohols: differentiation of neural stem cells and modulation of neuroinflammation
Hauss, Frederique; Liu, Jiawei; Michelucci, Alessandro; Coowar, Djalil; Morga, Eleonora; Heuschling, Paul; Luu, Bang

in Bioorganic & Medicinal Chemistry Letters (2007), 17(15), 4218-4222

See detailConstitutive suppressor of cytokine signaling 3 expression confers a growth advantage to a human melanoma cell line
Komyod, W.; Böhm, M.; Metze, D.; Heinrich, P. C.; Behrmann, Iris

in Molecular Cancer Research (2007), 5(3), 271-81

See detailRecombinant interleukin-24 lacks apoptosis-inducing properties in melanoma cells
Kreis, Stephanie; Philippidou, Demetra; Margue, Christiane; Rolvering, Catherine; Haan, Claude; Dumoutier, L.; Renauld, J. C.; Behrmann, Iris

in PLoS ONE (2007), 2(12), 1300

See detailSpinal cord injuries entering the Fas(t) lane.
Letellier, Elisabeth; Martin-Villalba, Ana

in Neurosurgery (2007), 6

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See detailElongation of axons during regeneration involves retinal crystallin beta b2 (crybb2).
Liedtke, Thomas; Schwamborn, Jens Christian; Schroer, Uwe; Thanos, Solon

in Molecular & cellular proteomics : MCP (2007), 6(5), 895-907

See detailAcute parkinsonism with corresponding lesions in the basal ganglia after heroin abuse.
Matzler, Walter; Nagele, Thomas; Gasser, Thomas; Krüger, Rejko

in Neurology (2007), 68(6), 414

See detailCharacterization of the Interleukin (IL)-6 Inhibitor IL-6-RFP: fused receptor domains act as high affinity cytokine-binding proteins.
Metz, Silke; Wiesinger, Monique; Vogt, Michael; Lauks, Heike; Schmalzing, Gunther; Heinrich, Peter C.; Muller-Newen, Gerhard

in Journal of Biological Chemistry (2007), 282(2), 1238-48

See detailThe integrin binding site 2 (IBS2) in the talin rod domain is essential for linking integrin beta subunits to the cytoskeleton.
Moes, Michèle; Rodius, Sophie; Coleman, Stacey J.; Monkley, Susan J.; Goormaghtigh, Erik; Tremuth, Laurent; Kox, Corinne; van der Holst, Patrick P. G.; Critchley, David R.; Kieffer, Nelly

in The Journal of biological chemistry (2007), 282(23), 17280-8

See detailDesign and evaluation of Actichip, a thematic microarray for the study of the actin cytoskeleton
Muller, J.; Mehlen, A.; Vetter, G.; Yatskou, M.; Muller, A.; Chalmel, F.; Poch, O.; Friederich, Evelyne; Vallar, L.

in BMC Genomics (2007), 8

See detailComplete loss of PTEN expression as a possible early prognostic marker for prostate cancer metastasis.
Schmitz, Martine; Grignard, Gerard; Margue, Christiane; Dippel, Walter; Capesius, Catherine; Mossong, Joel; Nathan, Michel; Giacchi, Sandro; Scheiden, Rene; Kieffer, Nelly

in International Journal of Cancer = Journal International du Cancer (2007), 120(6), 1284-92

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See detailThe histone deacetylase inhibitor trichostatin A mediates upregulation of 5-lipoxygenase promoter activity by recruitment of Sp1 to distinct GC-boxes
Schnur, N.; Seuter, Sabine; Katryniok, C.; Rådmark, O.; Steinhilber, D.

in Biochimica et Biophysica Acta (2007), 1771(10), 1271-1282

See detailTranscranial ultrasound in different monogenetic subtypes of Parkinson's disease.
Schweitzer, Katherine J.; Brussel, Theresa; Leitner, Petra; Krüger, Rejko; Bauer, Peter; Woitalla, Dirk; Tomiuk, Jurgen; Gasser, Thomas; Berg, Daniela

in Journal of neurology (2007), 254(5), 613-6

See detailSTAT1 regulates p73-mediated Bax gene expression
Soond, S. M.; Carroll, C.; Townsend, P. A.; Sayan, E.; Melino, G.; Behrmann, Iris; Knight, R. A.; Latchman, D. S.; Stephanou, A.

in FEBS Letters (2007), 581(6), 1217-26

See detailIdentification of a novel BBS gene (BBS12) highlights the major role of a vertebrate-specific branch of chaperonin-related proteins in Bardet-Biedl syndrome.
Stoetzel, Corinne; Muller, Jean; Laurier, Virginie; Davis, Erica E.; Zaghloul, Norann A.; Vicaire, Serge; Jacquelin, Cecile; Plewniak, Frederic; Leitch, Carmen C.; Sarda, Pierre; Hamel, Christian; de Ravel, Thomy J. L.; Lewis, Richard Alan; Friederich, Evelyne; Thibault, Christelle; Danse, Jean-Marc; Verloes, Alain; Bonneau, Dominique; Katsanis, Nicholas; Poch, Olivier; Mandel, Jean-Louis; Dollfus, Helene

in American Journal of Human Genetics (2007), 80(1), 1-11

See detailModeling and Analysis of UVB Influence on IL-1 induced NF-kappaB Signaling
Witt, Johannes; Husser, Sebastian; Kulms, Dagmar; Barisic, Sandra; Sawodny, Oliver; Sauter, Thomas

in Proceedings of the FOSBE, September 9-12, Stuttgart, Germany (2007)

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2006

See detailA quantitative approach to catabolite repression in Escherichia coli.
Bettenbrock, Katja; Fischer, Sophia; Kremling, Andreas; Jahreis, Knut; Sauter, Thomas; Gilles, Ernst-Dieter

in Journal of Biological Chemistry (2006), 281(5), 2578-84

See detailModulation by cADPr of Ca2+ mobilization and oxidative response in dimethylsulfoxide- or retinoic acid-differentiated HL-60 cells
Bréchard, Sabrina; Brunello, A.; Bueb, Jean-Luc; Tschirhart, Eric

in Biochimica et Biophysica Acta (2006), 1763(1), 129-36

See detailA domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks.
Conzelmann, Holger; Saez-Rodriguez, Julio; Sauter, Thomas; Kholodenko, Boris N.; Gilles, Ernst D.

in BMC Bioinformatics (2006), 7

See detailSensitivity analysis of programmed cell death and implications for crosstalk phenomena during Tumor Necrosis Factor stimulation
Eissing, Thomas; Bullinger, Eric; Waldherr, Steffen; Gondro, Cedric; Sawodny, Oliver; Allgöwer, Frank; Scheurich, Peter; Sauter, Thomas

in Proceedings of IEEE International Conference on Control Applications (CCA), October 4-6, 2006, Technische Universität München, Germany (2006)

See detailLack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study.
Elbaz, Alexis; Nelson, Lorene M.; Payami, Haydeh; Ioannidis, John P. A.; Fiske, Brian K.; Annesi, Grazia; Carmine Belin, Andrea; Factor, Stewart A.; Ferrarese, Carlo; Hadjigeorgiou, Georgios M.; Higgins, Donald S.; Kawakami, Hideshi; Krüger, Rejko; Marder, Karen S.; Mayeux, Richard P.; Mellick, George D.; Nutt, John G.; Ritz, Beate; Samii, Ali; Tanner, Caroline M.; Van Broeckhoven, Christine; Van Den Eeden, Stephen K.; Wirdefeldt, Karin; Zabetian, Cyrus P.; Dehem, Marie; Montimurro, Jennifer S.; Southwick, Audrey; Myers, Richard M.; Trikalinos, Thomas A.

in Lancet neurology (2006), 5(11), 917-23

See detailJaks and cytokine receptors - an intimate relationship
Haan, Claude; Kreis, Stephanie; Margue, Christiane; Behrmann, Iris

in Biochemical Pharmacology (2006), 72(11), 1538-46

See detailModeling the VPAC2-activated cAMP/PKA signaling pathway: from receptor to circadian clock gene induction.
Hao, Haiping; Zak, Daniel E.; Sauter, Thomas; Schwaber, James; Ogunnaike, Babatunde A.

in Biophysical Journal (2006), 90(5), 1560-71

See detailPhosphorylation on Ser5 increases the F-actin-binding activity of L-plastin and promotes its targeting to sites of actin assembly in cells
Janji, B.; Giganti, A.; De Corte, V.; Catillon, M.; Bruyneel, E.; Lentz, D.; Plastino, J.; Gettemans, J.; Friederich, Evelyne

in Journal of Cell Science (2006), 119(9), 1947-1960

See detailCollaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease.
Maraganore, Demetrius M.; de Andrade, Mariza; Elbaz, Alexis; Farrer, Matthew J.; Ioannidis, John P.; Krüger, Rejko; Rocca, Walter A.; Schneider, Nicole K.; Lesnick, Timothy G.; Lincoln, Sarah J.; Hulihan, Mary M.; Aasly, Jan O.; Ashizawa, Tetsuo; Chartier-Harlin, Marie-Christine; Checkoway, Harvey; Ferrarese, Carlo; Hadjigeorgiou, Georgios; Hattori, Nobutaka; Kawakami, Hideshi; Lambert, Jean-Charles; Lynch, Timothy; Mellick, George D.; Papapetropoulos, Spiridon; Parsian, Abbas; Quattrone, Aldo; Riess, Olaf; Tan, Eng-King; Van Broeckhoven, Christine

in JAMA : the journal of the American Medical Association (2006), 296(6), 661-70

See detailRosuvastatin treatment protects against nitrate-induced oxidative stress in eNOS knockout mice: implication of the NAD(P)H oxidase pathway
Otto, A.; Fontaine, J.; Tschirhart, Eric; Fontaine, D.; Berkenboom, G.

in British Journal of Pharmacology (2006), 148(4), 544-52

See detailThree dileucine-like motifs within the interbox1/2 region of the human oncostatin M receptor prevent efficient surface expression in the absence of an associated Janus kinase
Radtke, S.; Jörissen, A.; de Leur, H. S.; Heinrich, P. C.; Behrmann, Iris

in Journal of Biological Chemistry (2006), 281(7), 4024-34

See detailGenetic causes of Parkinson's disease: extending the pathway.
Riess, O.; Krüger, Rejko; Hochstrasser, H.; Soehn, A. S.; Nuber, S.; Franck, T.; Berg, D.

in Journal of neural transmission. Supplementum (2006), (70), 181-9

See detailRGD, the Rho'd to cell spreading
Salsmann, Alexandre; Schaffner-Reckinger, Elisabeth; Kieffer, Nelly

in European Journal of Cell Biology (2006), 85(3-4), 249-254

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See detailGTPases and the control of neuronal polarity.
Schwamborn, Jens Christian; Li, Yinghua; Puschel, Andreas W.

in Methods in Enzymology (2006), 406

See detailBiological responses to PDGF-BB versus PDGF-DD in human mesangial cells
van Roeyen, C. R.; Ostendorf, T.; Denecke, B.; Bokemeyer, D.; Behrmann, Iris; Strutz, F.; Lichenstein, H. S.; LaRochelle, W. J.; Pena, C. E.; Chaudhuri, A.; Floege, J.

in Kidney International (2006), 69(8), 1393-402

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2005

See detailInterleukin-8 primes oxidative burst in neutrophil-like HL-60 through changes in cytosolic calcium
Bréchard, Sabrina; Bueb, Jean-Luc; Tschirhart, Eric

in Cell Calcium (2005), 37(6), 531-40

See detailMolecular basis for dissimilar nuclear trafficking of the actin-bundling protein isoforms T- and L-plastin.
Delanote, Veerle; Van Impe, Katrien; De Corte, Veerle; Bruyneel, Erik; Vetter, Guillaume; Boucherie, Ciska; Mareel, Marc; Vandekerckhove, Joel; Friederich, Evelyne; Gettemans, Jan

in Traffic (Copenhagen, Denmark) (2005), 6(4), 335-45

See detailThe Use of In Vitro Systems for Evaluating Immunotoxicity: The Report and Recommendations of an ECVAM Workshop
Gennari, Alessandra; Ban, Masarin; Braun, Armin; Casati, Silvia; Corsini, Emanuela; Dastych, Jaroslaw; Descotes, Jacques; Hartung, Thomas; Hooghe-Peters, Robert; House, Robert; Pallardy, Marc; Pieters, Raymond; Reid, Lynnda; Tryphonas, Helen; Tschirhart, Eric; Tuschl, Helga; Vandebriel, Rob; Gribaldo, Laura

in Journal of Immunotoxicology (2005), 2(2), 61-83

See detailActin-filament cross-linking protein T-plastin increases Arp2/3-mediated actin-based movement
Giganti, A.; Plastino, J.; Janji, B.; Van Troys, M.; Lentz, D.; Ampe, C.; Sykes, C.; Friederich, Evelyne

in Journal of Cell Science (2005), 118(6), 1255-1265

See detailMultiple reasons for an inefficient STAT1 response upon IL-6-type cytokine stimulation
Haan, Serge; Keller, J. F.; Behrmann, Iris; Heinrich, P. C.; Haan, Claude

in Cellular Signalling (2005), 17(12), 1542-50

See detailPromoter-hypermethylation is causing functional relevant downregulation of methylthioadenosine phosphorylase (MTAP) expression in hepatocellular carcinoma
Hellerbrand, C.; Mühlbauer, M.; Wallner, S.; Schuierer, M.; Behrmann, Iris; Bataille, F.; Weiss, T.; Schölmerich, J.; Bosserhoff, A. K.

in Carcinogenesis (2005), 27(1), 64-72

See detailFunctional relevance of ceruloplasmin mutations in Parkinson's disease.
Hochstrasser, Helmine; Tomiuk, Jurgen; Walter, Uwe; Behnke, Stefanie; Spiegel, Jorg; Krüger, Rejko; Becker, Georg; Riess, Olaf; Berg, Daniela

in FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2005), 19(13), 1851-3

See detailThe role of alpha-synuclein gene multiplications in early-onset Parkinson's disease and dementia with Lewy bodies.
Hofer, A.; Berg, D.; Asmus, F.; Niwar, M.; Ransmayr, G.; Riemenschneider, M.; Bonelli, S.-B.; Steffelbauer, M.; Ceballos-Baumann, A.; Haussermann, P.; Behnke, S.; Krüger, Rejko; Prestel, J.; Sharma, M.; Zimprich, A.; Riess, O.; Gasser, T.

in Journal of neural transmission (Vienna, Austria : 1996) (2005), 112(9), 1249-54

See detailAre STATS arginine-methylated?
Komyod, W.; Bauer, U. M.; Heinrich, P. C.; Haan, Serge; Behrmann, Iris

in Journal of Biological Chemistry (2005), 280(23), 21700-5

See detailThe intermediate filament protein vimentin binds specifically to a recombinant integrin α2/β1 cytoplasmic tail complex and co-localizes with native α2/β1 in endothelial cell focal adhesions
Kreis, Stephanie; Schönfeld, H.-J. B; Melchior, C. A; Steiner, B. B C; Kieffer, N. A

in Experimental Cell Research (2005), 305(1), 110-121

See detailThe Jak1 SH2 domain does not fulfill a classical SH2 function in Jak/STAT signaling but plays a structural role for receptor interaction and up-regulation of receptor surface expression
Radtke, S.; Haan, Serge; Jörissen, A.; Hermanns, H. M.; Diefenbach, S.; Smyczek, T.; Schmitz-Vandeleur, H.; Heinrich, P. C.; Behrmann, Iris; Haan, Claude

in Journal of Biological Chemistry (2005), 280(27), 25760-8

See detailA new functional role of the fibrinogen RGD motif as the molecular switch that selectively triggers integrin alphaIIbbeta3-dependent RhoA activation during cell spreading
Salsmann, Alexandre; Schaffner-Reckinger, Elisabeth; Kabile, Fabrice; Plançon, Sébastien; Kieffer, Nelly

in Journal of Biological Chemistry (2005), 280(39), 33610-33619

See detailLoss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease.
Strauss, Karsten M.; Martins, Luisa; Plun-Favreau, Helene; Marx, Frank P.; Kautzmann, Sabine; Berg, Daniela; Gasser, Thomas; Wszolek, Zbginiew; Muller, Thomas; Bornemann, Antje; Wolburg, Hartwig; Downward, Julian; Riess, Olaf; Schulz, Jorg B.; Krüger, Rejko

in Human molecular genetics (2005), 14(15), 2099-111

See detailOxidative stress activates MMP-2 in cultured human coronary smooth muscle cells
Valentin, F.; Bueb, Jean-Luc; Kieffer, P.; Tschirhart, Eric; Atkinson, J.

in Fundamental & Clinical Pharmacology (2005), 19(6), 661-7

See detailSTAT5 contributes to interferon resistance of melanoma cells
Wellbrock, C.; Weisser, C.; Hassel, J. C.; Fischer, P.; Becker, J.; Vetter, C. S.; Behrmann, Iris; Kortylewski, M.; Heinrich, P. C.; Schartl, M.

in Current Biology (2005), 15(18), 1629-39

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2004

See detailJanus kinase (Jak) subcellular localization revisited: the exclusive membrane localization of endogenous Janus kinase 1 by cytokine receptor interaction uncovers the Jak.receptor complex to be equivalent to a receptor tyrosine kinase
Behrmann, Iris; Smyczek, Tanja; Heinrich, Peter C.; Schmitz-Van de Leur, Hildegard; Komyod, Waraporn; Giese, Bernd; Muller-Newen, Gerhard; Haan, Serge; Haan, Claude

in Journal of Biological Chemistry (2004), 279(34), 35486-93

See detailReduction of mathematical models of signal transduction networks: simulation-based approach applied to EGF receptor signalling.
Conzelmann, H.; Saez-Rodriguez, J.; Sauter, Thomas; Bullinger, E.; Allgower, F.; Gilles, E. D.

in Systems biology (2004), 1(1), 159-69

See detailThe role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling
Fischer, P.; Lehmann, U.; Sobota, R. M.; Schmitz, J.; Niemand, C.; Linnemann, S.; Haan, Serge; Behrmann, Iris; Yoshimura, A.; Johnston, J. A.; Müller-Newen, G.; Heinrich, P. C.; Schaper, F.

in Biochemical Journal (2004), 378(Pt 2), 449-60

See detailScreening for mutations in synaptotagmin XI in Parkinson's disease.
Glass, A. S.; Huynh, D. P.; Franck, Th; Woitalla, D.; Muller, Th; Pulst, S. M.; Berg, D.; Krüger, Rejko; Riess, O.

in Journal of neural transmission. Supplementum (2004), (68), 21-8

See detailExtended mutation analysis and association studies of Nurr1 (NR4A2) in Parkinson disease.
Hering, R.; Petrovic, S.; Mietz, E.-M.; Holzmann, C.; Berg, D.; Bauer, P.; Woitalla, D.; Muller, T.; Berger, K.; Krüger, Rejko; Riess, O.

in Neurology (2004), 62(7), 1231-2

See detailNovel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7).
Hering, Robert; Strauss, Karsten M.; Tao, Xiao; Bauer, Andreas; Woitalla, Dirk; Mietz, Eva-Maria; Petrovic, Slobodanka; Bauer, Peter; Schaible, Wilhelm; Muller, Thomas; Schols, Ludger; Klein, Christine; Berg, Daniela; Meyer, Philipp T.; Schulz, Jorg B.; Wollnik, Bernd; Tong, Liang; Krüger, Rejko; Riess, Olaf

in Human mutation (2004), 24(4), 321-9

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See detailThe effect of recombinant IgG antibodies against the leucine-33 form of the platelet beta3 integrin (HPA-1a) on platelet function.
Joutsi-Korhonen, Lotta; Preston, Sandy; Smethurst, Peter A.; Ijsseldijk, Martin; Schaffner-Reckinger, Elisabeth; Armour, Kathryn L.; Watkins, Nicholas A.; Clark, Michael R.; de Groot, Philip G.; Farndale, Richard W.; Ouwehand, Willem H.; Williamson, Lorna M.

in Thrombosis and haemostasis (2004), 91(4), 743-54

See detailInterferon-gamma-mediated growth regulation of melanoma cells: involvement of STAT1-dependent and STAT1-independent signals
Kortylewski, M.; Komyod, W.; Kauffmann, M. E.; Bosserhoff, A. K.; Heinrich, P. C.; Behrmann, Iris

in Journal of Investigative Dermatology (2004), 122(2), 414-22

See detailTowards whole cell "in silico" models for cellular systems: model set-up and model validation
Kremling, A.; Bettenbrock, K.; Fischer, S.; Ginkel, M.; Sauter, Thomas; Gilles, E. D.

in Lecture Notes in Control and Information Sciences: Proceedings of the first multidisciplinary international symposium on Positive Systems (2004)

See detailTime hierarchies in the Escherichia coli carbohydrate uptake and metabolism.
Kremling, A.; Fischer, S.; Sauter, Thomas; Bettenbrock, K.; Gilles, E. D.

in Bio Systems (2004), 73(1), 57-71

See detailA benchmark for methods in reverse engineering and model discrimination: problem formulation and solutions.
Kremling, Andreas; Fischer, Sophia; Gadkar, Kapil; Doyle, Francis J.; Sauter, Thomas; Bullinger, Eric; Allgower, Frank; Gilles, Ernst D.

in Genome Research (2004), 14(9), 1773-85

See detailGenes in familial parkinsonism and their role in sporadic Parkinson's disease.
Krüger, Rejko

in Journal of neurology (2004), 251 Suppl 6

See detailThe role of synphilin-1 in synaptic function and protein degradation.
Krüger, Rejko

in Cell and Tissue Research (2004), 318(1), 195-9

See detailUCHL1 is a Parkinson's disease susceptibility gene.
Maraganore, Demetrius M.; Lesnick, Timothy G.; Elbaz, Alexis; Chartier-Harlin, Marie-Christine; Gasser, Thomas; Krüger, Rejko; Hattori, Nobutaka; Mellick, George D.; Quattrone, Aldo; Satoh, Jun-Ichi; Toda, Tatsushi; Wang, Jian; Ioannidis, John P. A.; de Andrade, Mariza; Rocca, Walter A.

in Annals of neurology (2004), 55(4), 512-21

See detailAntiapoptotic effects of budipine.
Muller, T.; Przuntek, H.; Krüger, Rejko; Mackowiak, A.

in Journal of neural transmission (Vienna, Austria : 1996) (2004), 111(10-11), 1365-73

See detailDetailed Mathematical Modeling of Metabolic and Regulatory Networks
Sauter, Thomas; Bullinger, E.

in BIOforum Europe (2004), 02

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See detailSemaphorin 3A stimulates neurite extension and regulates gene expression in PC12 cells.
Schwamborn, Jens Christian; Fiore, Roberto; Bagnard, Dominique; Kappler, Joachim; Kaltschmidt, Christian; Puschel, Andreas W.

in Journal of Biological Chemistry (2004), 279(30), 30923-6

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See detailThe sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity.
Schwamborn, Jens Christian; Puschel, Andreas W.

in Nature Neuroscience (2004), 7(9), 923-9

See detailNew developments in diagnosis and treatment of Parkinson's disease--from basic science to clinical applications.
Storch, Alexander; Hofer, Anne; Krüger, Rejko; Schulz, Jorg B.; Winkler, Jurgen; Gerlach, Manfred

in Journal of neurology (2004), 251 Suppl 6

See detailA fluorescence cell biology approach to map the second integrin-binding site of talin to a 130-amino acid sequence within the rod domain
Tremuth, L. A; Kreis, Stephanie; Melchior, C. A; Hoebeke, J. B; Rondé, P. C D; Plançon, Sébastien; Takeda, K. C; Kieffer, N. A

in Journal of Biological Chemistry (2004), 279(21), 22258-22266

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2003

See detailCharacterization of methylthioadenosin phosphorylase (MTAP) expression in malignant melanoma
Behrmann, Iris; Wallner, S.; Komyod, W.; Heinrich, P. C.; Schuierer, M.; Buettner, R.; Bosserhoff, A. K.

in American Journal of Pathology (2003), 163(2), 683-90

See detailAn approach for dividing models of biological reaction networks into functional units
Ederer, M.; Sauter, Thomas; Bullinger, E.; Gilles, E. D.; Allgöwer, F.

in Simulation (2003), 79

See detailLong term association of the cytokine receptor gp130 and the Janus kinase Jak1 revealed by FRAP analysis
Giese, B.; Au-Yeung, C. K.; Herrmann, A.; Diefenbach, S.; Haan, Claude; Küster, A.; Wortmann, S. B.; Roderburg, C.; Heinrich, P. C.; Behrmann, Iris; Müller-Newen, G.

in Journal of Biological Chemistry (2003), 278(40), 39205-13

See detailThe actin cytoskeleton as a therapeutic target: state of the art and future directions.
Giganti, Adeline; Friederich, Evelyne

in Progress in cell cycle research (2003), 5

See detailPolymorphisms of the alpha-synuclein promoter: expression analyses and association studies in Parkinson's disease.
Holzmann, C.; Krüger, Rejko; Saecker, A. M. M. Vieira; Schmitt, I.; Schols, L.; Berger, K.; Riess, O.

in Journal of neural transmission (Vienna, Austria : 1996) (2003), 110(1), 67-76

See detailHaploinsufficiency at the alpha-synuclein gene underlies phenotypic severity in familial Parkinson's disease.
Kobayashi, Hirokazu; Krüger, Rejko; Markopoulou, Katerina; Wszolek, Zbigniew; Chase, Bruce; Taka, Hikaru; Mineki, Reiko; Murayama, Kimie; Riess, Olaf; Mizuno, Yoshikuni; Hattori, Nobutaka

in Brain : a journal of neurology (2003), 126(Pt 1), 32-42

See detailAkt modulates STAT3-mediated gene expression through a FKHR (FOXO1a)-dependent mechanism
Kortylewski, M.; Feld, F.; Krüger, K. D.; Bahrenberg, G.; Roth, R. A.; Joost, H. G.; Heinrich, P. C.; Behrmann, Iris; Barthel, A.

in Journal of Biological Chemistry (2003), 278(7), 5242-9

See detailMutation analysis of the neurofilament M gene in Parkinson's disease.
Krüger, Rejko; Fischer, Christian; Schulte, Thorsten; Strauss, Karsten M.; Muller, Thomas; Woitalla, Dirk; Berg, Daniela; Hungs, Marcel; Gobbele, Rene; Berger, Klaus; Epplen, Jorg T.; Riess, Olaf; Schols, Ludger

in Neuroscience letters (2003), 351(2), 125-9

See detailIdentification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease.
Marx, Frank P.; Holzmann, Carsten; Strauss, Karsten M.; Li, Lei; Eberhardt, Olaf; Gerhardt, Ellen; Cookson, Mark R.; Hernandez, Dena; Farrer, Matt J.; Kachergus, Jennifer; Engelender, Simone; Ross, Christopher A.; Berger, Klaus; Schols, Ludger; Schulz, Jorg B.; Riess, Olaf; Krüger, Rejko

in Human molecular genetics (2003), 12(11), 1223-31

See detailTherapeutic strategies for Parkinson's disease based on data derived from genetic research.
Riess, Olaf; Berg, Daniela; Krüger, Rejko; Schulz, Jorg B.

in Journal of neurology (2003), 250 Suppl 1

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See detailBeta3 integrins: major therapeutic targets of the near future.
Schaffner-Reckinger, Elisabeth

in Bulletin de la Société des Sciences Médicales du Grand-Duché de Luxembourg (2003), (1), 23-34

See detailModulation of disease risk according to a cathepsin D / apolipoprotein E genotype in Parkinson's disease.
Schulte, T.; Bohringer, S.; Schols, L.; Muller, T.; Fischer, C.; Riess, O.; Przuntek, H.; Berger, K.; Epplen, J. T.; Krüger, Rejko

in Journal of neural transmission (Vienna, Austria : 1996) (2003), 110(7), 749-55

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See detailMicroarray analysis of tumor necrosis factor alpha induced gene expression in U373 human glioblastoma cells.
Schwamborn, Jens Christian; Lindecke, Antje; Elvers, Margitta; Horejschi, Volker; Kerick, Martin; Rafigh, Mehran; Pfeiffer, Julia; Prullage, Maria; Kaltschmidt, Barbara; Kaltschmidt, Christian

in BMC Genomics (2003), 4(1), 46

See detailGiant cavernoma of the brain stem: value of delayed MR imaging after contrast injection.
Thiex, R.; Krüger, Rejko; Friese, S.; Gronewaller, E.; Kuker, W.

in European radiology (2003), 13 Suppl 6

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2002

See detailIdentification of the critical sequence elements in the cytoplasmic domain of leptin receptor isoforms required for Janus kinase/signal transducer and activator of transcription activation by receptor heterodimers
Bahrenberg, G.; Behrmann, Iris; Barthel, A.; Hekerman, P.; Heinrich, P. C.; Joost, H. G.; Becker, Werner

in Molecular Endocrinology (2002), 16(4), 859-72

See detailOrientational constraints of the gp130 intracellular juxtamembrane domain for signaling
Greiser, J. S.; Stross, C.; Heinrich, P. C.; Behrmann, Iris; Hermanns, H. M.

in Journal of Biological Chemistry (2002), 277(30), 26959-65

See detailParkinson's disease: one biochemical pathway to fit all genes?
Krüger, Rejko; Eberhardt, Olaf; Riess, Olaf; Schulz, Jorg B.

in Trends in molecular medicine (2002), 8(5), 236-40

See detailSHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130
Lehmann, U.; Schmitz, J.; Weissenbach, M.; Sobota, R. M.; Hortner, M.; Friederichs, K.; Behrmann, Iris; Tsiaris, W.; Sasaki, A.; Schneider-Mergener, J.; Yoshimura, A.; Neel, B. G.; Heinrich, P. C.; Schaper, F.

in Journal of Biological Chemistry (2002), 278(1), 661-71

See detailPromoter characterization and genomic organization of the gene encoding integrin-linked kinase 1
Melchior, C. A; Kreis, Stephanie; Janji, B. B; Kieffer, N. A

in Biochimica et Biophysica Acta-Gene Structure and Expression (2002), 1575(1-3), 117-122

See detailIntegrin alpha(v)beta3 expression confers on tumor cells a greater propensity to metastasize to bone.
Pecheur, Isabelle; Peyruchaud, Olivier; Serre, Claire-Marie; Guglielmi, Julien; Voland, Carole; Bourre, Francois; Margue, Christiane; Cohen-Solal, Martine; Buffet, Annie; Kieffer, Nelly; Clezardin, Philippe

in FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2002), 16(10), 1266-8

See detailNovel role of Janus kinase 1 in the regulation of oncostatin M receptor surface expression
Radtke, S.; Hermanns, H. M.; Haan, Claude; Schmitz-Van De Leur, H.; Gascan, H.; Heinrich, P. C.; Behrmann, Iris

in Journal of Biological Chemistry (2002), 277(13), 11297-305

See detailNeurofilament L gene is not a genetic factor of sporadic and familial Parkinson's disease.
Rahner, Nils; Holzmann, Carsten; Krüger, Rejko; Schols, Ludger; Berger, Klaus; Riess, Olaf

in Brain research (2002), 951(1), 82-6

See detailSpectrum of phenotypes and genotypes in Parkinson's disease.
Riess, Olaf; Krüger, Rejko; Schulz, Jorg B.

in Journal of neurology (2002), 249 Suppl 3

See detailThe matrix metalloproteinase 9 (mmp-9) hemopexin domain is a novel gelatin binding domain and acts as an antagonist
Roeb, E.; Schleinkofer, K.; Kernebeck, T.; Pötsch, S.; Jansen, B.; Behrmann, Iris; Matern, S.; Grötzinger, J.

in Journal of Biological Chemistry (2002), 277(52), 50326-32

See detailPolymorphisms in the interleukin-1 alpha and beta genes and the risk for Parkinson's disease.
Schulte, Thorsten; Schols, Ludger; Muller, Thomas; Woitalla, Dirk; Berger, Klaus; Krüger, Rejko

in Neuroscience letters (2002), 326(1), 70-2

See detail14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta.
Ubl, Andreas; Berg, Daniela; Holzmann, Carsten; Krüger, Rejko; Berger, Klaus; Arzberger, Thomas; Bornemann, Antje; Riess, Olaf

in Molecular Brain Research (2002), 108(1-2), 33-9

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See detailHPA-1a phenotype-genotype discrepancy reveals a naturally occurring Arg93Gln substitution in the platelet beta 3 integrin that disrupts the HPA-1a epitope.
Watkins, Nicholas A.; Schaffner-Reckinger, Elisabeth; Allen, David L.; Howkins, Graham J.; Brons, Nicolaas H. C.; Smith, Graham A.; Metcalfe, Paul; Murphy, Michael F.; Kieffer, Nelly; Ouwehand, Willem H.

in Blood (2002), 99(5), 1833-9

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See detailMutation analysis and association studies of nuclear factor-kappaB1 in sporadic Parkinson's disease patients.
Wintermeyer, P.; Riess, O.; Schols, L.; Przuntek, H.; Miterski, B.; Epplen, J. T.; Krüger, Rejko

in Journal of neural transmission (Vienna, Austria : 1996) (2002), 109(9), 1181-8

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2001

See detailInterleukin-6-resistant melanoma cells exhibit reduced activation of STAT3 and lack of inhibition of cyclin E-associated kinase activity
Böhm, M.; Schulte, U.; Funk, J. O.; Raghunath, M.; Behrmann, Iris; Kortylewski, M.; Heinrich, P. C.; Kues, T.; Luger, T. A.; Schwarz, T.

in Journal of Investigative Dermatology (2001), 117(1), 132-40

See detailReceptor-independent effects of natural cannabinoids in rat peritoneal mast cells in vitro
Bueb, Jean-Luc; Lambert, D. M.; Tschirhart, Eric

in Biochimica et Biophysica Acta (2001), 1538(2-3), 252-9

See detailActA and human zyxin harbour Arp2/3-independent actin-polymerization activity.
Fradelizi, J.; Noireaux, V.; Plastino, J.; Menichi, B.; Louvard, D.; Sykes, C.; Golsteyn, R. M.; Friederich, Evelyne

in Nature cell biology (2001), 3(8), 699-707

See detailMapping of a region within the N terminus of Jak1 involved in cytokine receptor interaction
Haan, Claude; Isharc, H.; Hermanns, H. M.; Schmitz-Van De Leur, H.; Kerr, I. M.; Heinrich, P. C.; Grötzinger, J.; Behrmann, Iris

in Journal of Biological Chemistry (2001), 276(40), 37451-8

See detailNon-redundant signal transduction of interleukin-6-type cytokines. The adapter protein Shc is specifically recruited to rhe oncostatin M receptor
Hermanns, H. M.; Radtke, S.; Schaper, F.; Heinrich, P. C.; Behrmann, Iris

in Journal of Biological Chemistry (2001), 275(52), 40742-8

See detailA region encompassing the FERM domain of Jak1 is necessary for binding to the cytokine receptor gp130
Hilkens, C. M.; Isharc, H.; Lillemeier, B. F.; Strobl, B.; Bates, P. A.; Behrmann, Iris; Kerr, I. M.

in FEBS Letters (2001), 505(1), 87-91

See detailMitogen-activated protein kinases control p27/Kip1 expression and growth of human melanoma cells
Kortylewski, M.; Heinrich, P. C.; Kauffmann, M. E.; Böhm, M.; MacKiewicz, A.; Behrmann, Iris

in Biochemical Journal (2001), 357(Pt 1), 297-303

See detailCytokine-mediated growth inhibition of human melanoma cells
Kortylewski, M.; Heinrich, P. C.; Mackiewicz, A.; Behrmann, Iris

in Advances in Experimental Medicine and Biology (2001), 495

See detailBiosystems Engineering: Applying methods from systems theory to biological systems
Kremling, A.; Sauter, Thomas; Bullinger, E.; Ederer, M.; Allgöwer, F.; Gilles, E. D.

in Proceedings of the 2nd International Conference on Systems Biology 4.-7.11.2001, Pasadena (2001)

See detailFamilial parkinsonism with synuclein pathology: clinical and PET studies of A30P mutation carriers.
Krüger, Rejko; Kuhn, W.; Leenders, K. L.; Sprengelmeyer, R.; Muller, T.; Woitalla, D.; Portman, A. T.; Maguire, R. P.; Veenma, L.; Schroder, U.; Schols, L.; Epplen, J. T.; Riess, O.; Przuntek, H.

in Neurology (2001), 56(10), 1355-62

See detailEvaluation of the gamma-synuclein gene in German Parkinson's disease patients.
Krüger, Rejko; Schols, L.; Muller, T.; Kuhn, W.; Woitalla, D.; Przuntek, H.; Epplen, J. T.; Riess, O.

in Neuroscience letters (2001), 310(2-3), 191-3

See detailSTAT3 is constitutively activated in Hodgkin cell lines
Kube, D.; Holtick, U.; Vockerodt, M.; Ahmadi, T.; Haier, B.; Behrmann, Iris; Heinrich, P. C.; Diehl, V.; Tesch, H.

in Blood (2001), 98(3), 762-70

See detailTargeting of zyxin to sites of actin membrane interaction and to the nucleus.
Nix, D. A.; Fradelizi, J.; Bockholt, S.; Menichi, B.; Louvard, D.; Friederich, Evelyne; Beckerle, M. C.

in The Journal of biological chemistry (2001), 276(37), 34759-67

See detailRole of G(i)-proteins in norepinephrine-mediated vasoconstriction in rat tail artery smooth muscle
Petitcolin, M. A.; Spitzbarth-Régrigny, E.; Bueb, Jean-Luc; Capdeville-Atkinson, C.; Tschirhart, Eric

in Biochemical Pharmacology (2001), 61(9), 1169-75

See detailLack of involvement of pertussis toxin-sensitive G-proteins in norepinephrine-induced vasoconstriction of rat aorta smooth muscle
Petitcolin, M. A.; Vandeputte, C.; Spitzbarth-Régrigny, E.; Bueb, Jean-Luc; Capdeville-Atkinson, C.; Tschirhart, Eric

in Biochemical Pharmacology (2001), 61(4), 485-91

Full Text
See detailGreen fluorescent protein (GFP) tagged to the cytoplasmic tail of alphaIIb or beta3 allows the expression of a fully functional integrin alphaIIb(beta3): effect of beta3GFP on alphaIIb(beta3) ligand binding.
Plançon, Sébastien; Morel-Kopp, M. C.; Schaffner-Reckinger, Elisabeth; Chen, P.; Kieffer, N.

in The Biochemical journal (2001), 357(Pt 2), 529-36

See detailA completely foreign receptor can mediate an interferon-gamma-like response
Strobl, B.; Arulampalam, V.; Isharc, H.; Newman, S. J.; Schlaak, J. F.; Watling, D.; Costa-Pereira, A. P.; Schaper, F.; Behrmann, Iris; Sheehan, K. C.; Schreiber, R. D.; Horn, F.; Heinrich, P. C.; Kerr, I. M.

in EMBO Journal (2001), 20(19), 5431-42

See detailRac-1-mediated O2- secretion requires Ca2+ influx in neutrophil-like HL-60 cells
Valentin, F.; Bueb, Jean-Luc; Capdeville-Atkinson, C.; Tschirhart, Eric

in Cell Calcium (2001), 29(6), 409-15

See detailNeutralizing monoclonal antibodies can potentiate IL-5 signaling
Zabeau, L.; Van der Heyden, J.; Broekaert, D.; Verhee, A.; Vandekerckhove, J.; Wu, S. J.; Chaiken, I.; Heinrich, P.; Behrmann, Iris; Tavernier, J.

in European Journal of Immunology (2001), 31(4), 1087-97

See detailHuman umbilical cord blood monocyte-derived eosinophils produce superoxide but not nitric oxide
Zardini, D. M.; Tschirhart, Eric

in Inflammation Research (2001), 50(7), 357-61

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2000

See detailSignal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: structural receptor requirements for signal attenuation
Anhuf, D.; Weissenbach, M.; Schmitz, J.; Sobota, R.; Hermanns, H. M.; Radtke, S.; Linnemann, S.; Behrmann, Iris; Heinrich, P. C.; Schaper, F.

in Journal of Immunology (2000), 165(5), 2535-43

See detailSignalling of interleukin-6 type cytokines via gp130, leukemia inhibitory factor (LIF) receptor and oncostatin M receptor
Behrmann, Iris; Hermanns, H. M.; Haan, Claude; Kortylewski, M.; Radtke, S.; Greiser, J. S.; Heinrich, P. C.

in European Cytokine Network (2000), 11(3), 491-2

See detailCharacterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteins.
Drees, B.; Friederich, Evelyne; Fradelizi, J.; Louvard, D.; Beckerle, M. C.; Golsteyn, R. M.

in The Journal of biological chemistry (2000), 275(29), 22503-11

See detailPlacental transfer and decay of maternally acquired antimeasles antibodies in Nigerian children
Hartter, H. K.; Oyedele, O. I.; Dietz, K.; Kreis, Stephanie; Hoffman, J. P.; Muller, Claude

in Pediatric Infectious Disease Journal (2000), 19(7), 635-641

See detailContributions of leukemia inhibitory factor receptor and oncostatin M receptor to signal transduction in heterodimeric complexes with glycoprotein 130
Hermanns, H. M.; Radtke, S.; Haan, Claude; Schmitz-Van de Leur, H.; Tavernier, J.; Heinrich, P. C.; Behrmann, Iris

in Journal of Immunology (2000), 163(12), 6651-8

See detailVillin-like actin-binding proteins are expressed ubiquitously in Arabidopsis.
Klahre, U.; Friederich, Evelyne; Kost, B.; Louvard, D.; Chua, N. H.

in Plant physiology (2000), 122(1), 35-48

See detailGenetic analysis of immunomodulating factors in sporadic Parkinson's disease.
Krüger, Rejko; Hardt, C.; Tschentscher, F.; Jackel, S.; Kuhn, W.; Muller, T.; Werner, J.; Woitalla, D.; Berg, D.; Kuhnl, N.; Fuchs, G. A.; Santos, E. J.; Przuntek, H.; Epplen, J. T.; Schols, L.; Riess, O.

in Journal of neural transmission (Vienna, Austria : 1996) (2000), 107(5), 553-62

See detailGenetic analysis of the alpha2-macroglobulin gene in early- and late-onset Parkinson's disease.
Krüger, Rejko; Menezes-Saecker, A. M.; Schols, L.; Kuhn, W.; Muller, T.; Woitalla, D.; Berg, D.; Berger, K.; Przuntek, H.; Epplen, J. T.; Riess, O.

in Neuroreport (2000), 11(11), 2439-42

See detailInvolvement of alpha-synuclein in Parkinson's disease and other neurodegenerative disorders.
Krüger, Rejko; Muller, T.; Riess, O.

in Journal of neural transmission (Vienna, Austria : 1996) (2000), 107(1), 31-40

See detailExpression patterns of L-plastin isoform in normal and carcinomatous breast tissues.
Lapillonne, A.; Coue, O.; Friederich, Evelyne; Nicolas, A.; Del Maestro, L.; Louvard, D.; Robine, S.; Sastre-Garau, X.

in Anticancer research (2000), 20(5A), 3177-82

See detailTranscriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHR
Margue, Christiane; Bernasconi, Michele; Barr, Frederik; Schäfer, Beat

in Oncogene (2000), 19(25), 2921

See detailPCR/SSCP detects reliably and efficiently DNA sequence variations in large scale screening projects.
Miterski, B.; Krüger, Rejko; Wintermeyer, P.; Epplen, J. T.

in Combinatorial chemistry & high throughput screening (2000), 3(3), 211-8

See detailGrowing an actin gel on spherical surfaces.
Noireaux, V.; Golsteyn, R. M.; Friederich, Evelyne; Prost, J.; Antony, C.; Louvard, D.; Sykes, C.

in Biophysical journal (2000), 78(3), 1643-54

See detailLPP, an actin cytoskeleton protein related to zyxin, harbors a nuclear export signal and transcriptional activation capacity.
Petit, M. M.; Fradelizi, J.; Golsteyn, R. M.; Ayoubi, T. A.; Menichi, B.; Louvard, D.; Van de Ven, W. J.; Friederich, Evelyne

in Molecular biology of the cell (2000), 11(1), 117-29

See detailGenetic influence on the development of Parkinson's disease.
Riess, O.; Kuhn, W.; Krüger, Rejko

in Journal of neurology (2000), 247 Suppl 2

See detailAn MMP-9 mutant without gelatinolytic activity as a novel TIMP-1-antagonist
Roeb, E.; Behrmann, Iris; Grötzinger, J.; Breuer, B.; Matern, S.

in FASEB Journal (2000), 14(12), 1671-3

See detailExtrapyramidal motor signs in degenerative ataxias.
Schols, L.; Peters, S.; Szymanski, S.; Krüger, Rejko; Lange, S.; Hardt, C.; Riess, O.; Przuntek, H.

in Archives of neurology (2000), 57(10), 1495-500

See detailPertussis toxin-sensitive G(i)-proteins and intracellular calcium sensitivity of vasoconstriction in the intact rat tail artery
Spitzbarth-Régrigny, E.; Petitcolin, M. A.; Bueb, Jean-Luc; Tschirhart, Eric; Atkinson, J.; Capdeville-Atkinson, C.

in British Journal of Pharmacology (2000), 131(7), 1337-44

See detailDifferential inhibition of IL-6-type cytokine-induced STAT activation by PMA
Terstegen, L.; Maassen, B. G.; Radtke, S.; Behrmann, Iris; Schaper, F.; Heinrich, P. C.; Graeve, L.; Gatsios, P.

in FEBS Letters (2000), 478(1-2), 100-4

See detailTermination of IL-6-induced STAT activation is independent of receptor internalization but requires de novo protein synthesis
Thiel, S.; Sommer, U.; Kortylewski, M.; Haan, Claude; Behrmann, Iris; Heinrich, P. C.; Graeve, L.

in FEBS Letters (2000), 470(1), 15-9

See detailMutation analysis and association studies of the UCHL1 gene in German Parkinson's disease patients.
Wintermeyer, P.; Krüger, Rejko; Kuhn, W.; Muller, T.; Woitalla, D.; Berg, D.; Becker, Gilles; Leroy, E.; Polymeropoulos, M.; Berger, K.; Przuntek, H.; Schols, L.; Epplen, J. T.; Riess, O.

in Neuroreport (2000), 11(10), 2079-82

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1999

See detailQuantitative measurement of proteins by western blotting with Cy5-coupled secondary antibodies.
Fradelizi, J.; Friederich, Evelyne; Beckerle, M. C.; Golsteyn, R. M.

in BioTechniques (1999), 26(3), 484-6488490

See detailVillin function in the organization of the actin cytoskeleton. Correlation of in vivo effects to its biochemical activities in vitro.
Friederich, Evelyne; Vancompernolle, K.; Louvard, D.; Vandekerckhove, J.

in The Journal of biological chemistry (1999), 274(38), 26751-60

See detailEffect of SK&F 96365 on extracellular Ca2+ -dependent O2- production in neutrophil-like HL-60 cells
Gallois, A.; Bueb, Jean-Luc; Tschirhart, Eric

in European Journal of Pharmacology (1999), 361(2-3), 293-8

See detailThe alpha1-antichymotrypsin A-allele in German Parkinson disease patients.
Grasbon-Frodl, E. M.; Egensperger, R.; Kosel, S.; Krüger, Rejko; Riess, O.; Mehraein, P.; Graeber, M. B.

in Journal of neural transmission (Vienna, Austria : 1996) (1999), 106(7-8), 729-36

See detailInterleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1
Kortylewski, M.; Heinrich, P. C.; Mackiewicz, A.; Schniertshauer, U.; Klingmüller, U.; Nakajima, K.; Hirano, T.; Horn, F.; Behrmann, Iris

in Oncogene (1999), 18(25), 3742-53

See detailAnalysis of the parkin deletion in sporadic and familial Parkinson's disease. Short communication.
Krüger, Rejko; Vieira-Sacker, A. M.; Kuhn, W.; Muller, T.; Woitalla, D.; Schols, L.; Przuntek, H.; Epplen, J. T.; Riess, O.

in Journal of neural transmission (Vienna, Austria : 1996) (1999), 106(2), 159-63

See detailIncreased susceptibility to sporadic Parkinson's disease by a certain combined alpha-synuclein/apolipoprotein E genotype.
Krüger, Rejko; Vieira-Saecker, A. M.; Kuhn, W.; Berg, D.; Muller, T.; Kuhnl, N.; Fuchs, G. A.; Storch, A.; Hungs, M.; Woitalla, D.; Przuntek, H.; Epplen, J. T.; Schols, L.; Riess, O.

in Annals of neurology (1999), 45(5), 611-7

See detailAnalogues and homologues of N-palmitoylethanolamide, a putative endogenous CB(2) cannabinoid, as potential ligands for the cannabinoid receptors
Lambert, D. M.; DiPaolo, F. G.; Sonveaux, P.; Kanyonyo, M.; Govaerts, S. J.; Hermans, E.; Bueb, Jean-Luc; Delzenne, N. M.; Tschirhart, Eric

in Biochimica et Biophysica Acta (1999), 1440(2-3), 266-74

See detailIdentification of a Leu-lle internalization motif within the cytoplasmic domain of the leukaemia inhibitory factor receptor
Thiel, S.; Behrmann, Iris; Timmermann, A.; Dahmen, H.; Müller-Newen, G.; Schaper, F.; Tavernier, J.; Pitard, V.; Heinrich, P. C.; Graeve, L.

in Biochemical Journal (1999), 339 (Pt 1)

See detailGenotypic and antigenic characterization of hemagglutinin proteins of African measles virus isolates
Truong, A. T.; Kreis, Stephanie; Ammerlaan, W.; Hartter, H. K.; Adu, F.; Omilabu, S. A.; Oyefolu, A. O.; Berbers, G. A. M.; Muller, Claude

in Virus Research (1999), 62(1), 89-95

See detailIsolation of measles virus from a naturally-immune, asymptomatically re-infected individual
Vardas, E. A B; Kreis, Stephanie

in Journal of Clinical Virology (1999), 13(3), 173-179

See detailCase report and molecular analysis of subacute sclerosing panencephalitis in a South African child
Vardas, E. A D; Leary, P. M. B; Yeats, J. C; Badrodien, W. B; Kreis, Stephanie

in Journal of Clinical Microbiology (1999), 37(3), 775-777

See detailRelease of O2- by human umbilical cord blood-derived eosinophils: role of intra- and extracellular calcium
Zardini, D. M.; Bueb, Jean-Luc; Tschirhart, Eric

in Cell Calcium (1999), 25(5), 381-9

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1998

See detailThe M2 muscarinic receptor antagonist methoctramine activates mast cells via pertussis toxin-sensitive G proteins
Chahdi, A.; Daeffler, L.; Bueb, Jean-Luc; Gies, J. P.; Landry, Y.

in Naunyn-Schmiedeberg's Archives of Pharmacology (1998), 357(4), 357-62

See detailInterleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
Heinrich, P. C.; Behrmann, Iris; Müller-Newen, G.; Schaper, F.; Graeve, L.

in Biochemical Journal (1998), 334 (Pt 2)

See detailAla30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease.
Krüger, Rejko; Kuhn, W.; Muller, T.; Woitalla, D.; Graeber, M.; Kosel, S.; Przuntek, H.; Epplen, J. T.; Schols, L.; Riess, O.

in Nature genetics (1998), 18(2), 106-8

See detailSelegiline as immunostimulant--a novel mechanism of action?
Muller, T.; Kuhn, W.; Krüger, Rejko; Przuntek, H.

in Journal of neural transmission. Supplementum (1998), 52

See detailGenetic dissection of familial Parkinson's disease.
Riess, O.; Jakes, R.; Krüger, Rejko

in Molecular medicine today (1998), 4(10), 438-44

Full Text
See detailDistinct involvement of beta3 integrin cytoplasmic domain tyrosine residues 747 and 759 in integrin-mediated cytoskeletal assembly and phosphotyrosine signaling.
Schaffner-Reckinger, Elisabeth; Gouon, V.; Melchior, Chantal; Plançon, Sébastien; Kieffer, N.

in The Journal of biological chemistry (1998), 273(20), 12623-32

See detailSpinocerebellar ataxia type 6: genotype and phenotype in German kindreds.
Schols, L.; Krüger, Rejko; Amoiridis, G.; Przuntek, H.; Epplen, J. T.; Riess, O.

in Journal of neurology, neurosurgery, and psychiatry (1998), 64(1), 67-73

See detailInternalization of the interleukin 6 signal transducer gp130 does not require activation of the Jak/STAT pathway
Thiel, S.; Behrmann, Iris; Dittrich, E.; Muys, L.; Tavernier, J.; Wijdenes, J.; Heinrich, P. C.; Graeve, L.

in Biochemical Journal (1998), 330 (Pt 1)

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1997

See detailA single STAT recruitment module in a chimeric cytokine receptor complex is sufficient for STAT activation
Behrmann, Iris; Janzen, C.; Gerhartz, C.; Schmitz-Van de Leur, H.; Hermanns, H.; Heesel, B.; Graeve, L.; Horn, F.; Tavernier, J.; Heinrich, P. C.

in Journal of Biological Chemistry (1997), 272(8), 5269-74

See detailQuantification of wild-type mitochondrial DNA and its 4.8-kb deletion in rat organs.
Filser, N.; Margue, Christiane; Richter, C.

in Biochemical and biophysical research communications (1997), 233(1), 102-7

See detailStructural and functional similarities between the human cytoskeletal protein zyxin and the ActA protein of Listeria monocytogenes.
Golsteyn, R. M.; Beckerle, M. C.; Koay, T.; Friederich, Evelyne

in Journal of cell science (1997), 110 ( Pt 16)

See detailThe role of actin binding proteins in epithelial morphogenesis: models based upon Listeria movement.
Golsteyn, R. M.; Louvard, D.; Friederich, Evelyne

in Biophysical chemistry (1997), 68(1-3), 73-82

See detailSequence analysis of the nucleocapsid gene of measles virus isolates from South Africa identifies a new genotype
Kreis, Stephanie; Vardas, E.; Whistler, T.

in Journal of General Virology (The) (1997), 78(7), 1581-1587

See detailRapid identification of measles virus strains by the heteroduplex mobility assay
Kreis, Stephanie; Whistler, T.

in Virus Research (1997), 47(2), 197-203

See detailMeasles virus transmission from infected to immune individuals - Implications for measles control and elimination
Vardas, E.; Andre, M.; Kreis, Stephanie; Zachariades, N.; Schoub, B.

in South African Medical Journal (1997), 87(12), 1709

See detailHuman umbilical cord blood-derived eosinophils cultured in the presence of IL-3 and IL-5 respond to fMLP with [Ca2+]i variation and O2- production
Zardini, D. M.; Heuschling, Paul; Gallois, A.; Bueb, Jean-Luc; Tschirhart, Eric

in Journal of Immunological Methods (1997), 205(1), 1-9

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1996

See detailEndothelin-1 does not modulate O2.release and [Ca(2+)]i variations in resting or differentiated HL-60 cells
Gallois, A.; Bueb, Jean-Luc; Tschirhart, Eric

in Fundamental & Clinical Pharmacology (1996), 10(1), 28-32

See detailCytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
Kischkel, F. C.; Hellbardt, S.; Behrmann, Iris; Germer, M.; Pawlita, M.; Krammer, P. H.; Peter, M. E.

in EMBO Journal (1996), 14(22), 5579-88

See detailSelegiline stimulates biosynthesis of cytokines interleukin-1 beta and interleukin-6.
Wilfried, K.; Muller, T.; Krüger, Rejko; Horst, P.

in Neuroreport (1996), 7(18), 2847-8

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1995

See detailStructure of the human APO-1 gene
Behrmann, Iris; Walczak, H.; Krammer, P. H.

in European Journal of Immunology (1995), 24(12), 3057-62

See detailA double-labelling fluorescent assay for concomitant measurements of [Ca2+]i and O2. production in human macrophages
Bueb, Jean-Luc; Gallois, A.; Schneider, J. C.; Parini, J. P.; Tschirhart, Eric

in Biochimica et Biophysica Acta (1995), 1244(1), 79-84

See detailAPO-I-mediated apoptosis in normal and malignant lymphocytes
Dhein, J.; Behrmann, Iris; Daniel, P. T.; Debatin, K. M.; Klas, C.; Möller, P.; Oehm, A.; Trauth, B. C.; Walczak, H.; Krammer, P. H.

in Biochemical Society Transactions (1995), 22(3), 598-600

See detailTargeting of Listeria monocytogenes ActA protein to the plasma membrane as a tool to dissect both actin-based cell morphogenesis and ActA function.
Friederich, Evelyne; Gouin, E.; Hellio, R.; Kocks, C.; Cossart, P.; Louvard, D.

in The EMBO journal (1995), 14(12), 2731-44

See detailThe role of APO-1-mediated apoptosis in the immune system
Krammer, P. H.; Dhein, J.; Walczak, H.; Behrmann, Iris; Mariani, S.; Matiba, B.; Fath, M.; Daniel, P. T.; Knipping, E.; Westendorp, M. O.

in Immunological Reviews (1995), 142

See detailConformational behaviour of a synthetic peptide of the C-terminus of villin that interacts with actin: an NMR, CD and stimulated annealing study.
Simenel, C.; Rose, T.; Goethals, M.; Vandekerckhove, J.; Friederich, Evelyne; Louvard, D.; Delepierre, M.

in International journal of peptide and protein research (1995), 45(6), 574-86

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1994

See detailFunctional differences between L- and T-plastin isoforms.
Arpin, M.; Friederich, Evelyne; Algrain, M.; Vernel, F.; Louvard, D.

in The Journal of cell biology (1994), 127(6 Pt 2), 1995-2008

See detailRegulation of apoptosis in the immune system
Krammer, P. H.; Behrmann, Iris; Daniel, P. T.; Dhein, J.; Debatin, K. M.

in Current Opinion in Immunology (1994), 6(2), 279-89

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1993

See detailAn epithelial-dependent contracting factor induced by calcium influx in guinea-pig trachea
Bertrand, C.; Da Silva, A.; Landry, Y.; Theodorsson, E.; Tschirhart, Eric

in Pulmonary Pharmacology (1993), 6(1), 69-76

See detailEpithelial factors: modulation of the airway smooth muscle tone
Bertrand, C.; Tschirhart, Eric

in Fundamental & Clinical Pharmacology (1993), 7(6), 261-73

See detailStructure-activity studies of bradykinin analogues on rat mast cell histamine release
Bueb, Jean-Luc; Mousli, M.; Landry, Y.; Regoli, D.

in Peptides (1993), 14(4), 685-9

See detailVillin-induced growth of microvilli is reversibly inhibited by cytochalasin D.
Friederich, Evelyne; Kreis, T. E.; Louvard, D.

in Journal of cell science (1993), 105 ( Pt 3)

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1992

See detailEpithelial modulation of thromboxane A2 and PAF involvement in IgE- and IgG-mediated guinea pig anaphylaxis
Bertrand, C.; Tschirhart, Eric; Landry, Y.

in Immunopharmacology (1992), 22(2), 115-25

See detailNatural polyamines stimulate G-proteins
Bueb, Jean-Luc; Da Silva, A.; Mousli, M.; Landry, Y.

in Biochemical Journal (1992), 282 (Pt 2)

See detailIn vivo analysis of functional domains from villin and gelsolin.
Finidori, J.; Friederich, Evelyne; Kwiatkowski, D. J.; Louvard, D.

in The Journal of cell biology (1992), 116(5), 1145-55

See detailAn actin-binding site containing a conserved motif of charged amino acid residues is essential for the morphogenic effect of villin.
Friederich, Evelyne; Vancompernolle, K.; Huet, C.; Goethals, M.; Finidori, J.; Vandekerckhove, J.; Louvard, D.

in Cell (1992), 70(1), 81-92

See detailPurification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen
Oehm, A.; Behrmann, Iris; Falk, W.; Pawlita, M.; Maier, G.; Klas, C.; Li-Weber, M.; Richards, S.; Dhein, J.; Trauth, B. C.

in Journal of Biological Chemistry (1992), 267(15), 10709-15

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1991

See detailSelective implication of thromboxane A2 and PAF-acether in two guinea pig anaphylactic models
Bertrand, C.; Tschirhart, Eric; Landry, Y.

in Agents and Actions. Supplements (1991), 31

See detailActivation of Gi-like proteins, a receptor-independent effect of kinins in mast cells
Bueb, Jean-Luc; Mousli, M.; Bronner, C.; Rouot, B.; Landry, Y.

in Molecular Pharmacology (1991), 38(6), 816-22

See detailMolecular basis for cellular effects of naturally occurring polyamines
Bueb, Jean-Luc; Mousli, M.; Landry, Y.

in Agents and Actions (1991), 33(1-2), 84-7

See detailEvidence for the interaction of mast cell-degranulating peptide with pertussis toxin-sensitive G proteins in mast cells
Mousli, M.; Bronner, C.; Bueb, Jean-Luc; Landry, Y.

in European Journal of Pharmacology (1991), 207(3), 249-55

See detailG-proteins as targets for non-immunological histamine releasers
Mousli, M.; Bueb, Jean-Luc; Rouot, B.; Landry, Y.; Bronner, C.

in Agents and Actions (1991), 33(1-2), 81-3

See detailEndothelins: functional and autoradiographic studies in guinea pig trachea
Tschirhart, Eric; Drijfhout, J. W.; Pelton, J. T.; Miller, R. C.; Jones, C. R.

in Journal of Pharmacology and Experimental Therapeutics (1991), 258(1), 381-7

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1990

See detailOxatomide and calcium: mechanisms involved in the secretion of mast cell mediators
Bueb, Jean-Luc; Landry, Y.

in Annales de Dermatologie et de Vénéréologie (1990), 117 Suppl 1

See detailA pertussis toxin-sensitive G protein is required to induce histamine release from rat peritoneal mast cells by bradykinin
Bueb, Jean-Luc; Mousli, M.; Landry, Y.; Bronner, C.

in Agents and Actions (1990), 30(1-2), 98-101

See detailFrom the structure to the function of villin, an actin-binding protein of the brush border.
Friederich, Evelyne; Pringault, E.; Arpin, M.; Louvard, D.

in BioEssays : news and reviews in molecular, cellular and developmental biology (1990), 12(9), 403-8

See detailNeuropeptides and inflammation: presumed mechanisms in neurogenic inflammation
Landry, Y.; Bloch, J. G.; Mousli, M.; Bueb, Jean-Luc; Bronner, C.

in Pathologie et Biologie (1990), 38(1), 53-6

See detailG protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides
Mousli, M.; Bueb, Jean-Luc; Bronner, C.; Rouot, B.; Landry, Y.

in Trends in Pharmacological Sciences (1990), 11(9), 358-62

See detailEvidence for the involvement of calcitonin gene-related peptide in the epithelium-dependent contraction of guinea-pig trachea in response to capsaicin
Tschirhart, Eric; Bertrand, C.; Theodorsson, E.; Landry, Y.

in Naunyn-Schmiedeberg's Archives of Pharmacology (1990), 342(2), 177-81

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1989

See detailNedocromil sodium inhibits IgE- and IgG-related antigen-induced contraction in guinea-pig trachea
Bertrand, C.; Tschirhart, Eric; Landry, Y.

in International Archives of Allergy and Applied Immunology (1989), 88(4), 439-46

See detailVillin induces microvilli growth and actin redistribution in transfected fibroblasts.
Friederich, Evelyne; Huet, C.; Arpin, M.; Louvard, D.

in Cell (1989), 59(3), 461-75

See detailActivation of rat peritoneal mast cells by substance P and mastoparan
Mousli, M.; Bronner, C.; Bueb, Jean-Luc; Tschirhart, Eric; Gies, J. P.; Landry, Y.

in Journal of Pharmacology and Experimental Therapeutics (1989), 250(1), 329-35

See detailContractile activity of the N-acylated C-terminal part of substance P7-11 in guinea pig trachea. Effect of epithelium removal
Tschirhart, Eric; Schmitt, P.; Bertrand, C.; Mayer, M.; Magneney, S.; Landry, Y.; Michelot, R.

in Naunyn-Schmiedeberg's Archives of Pharmacology (1989), 340(1), 107-10

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1987

See detailArachidonic acid metabolites and airway epithelium-dependent relaxant factor
Tschirhart, Eric; Frossard, N.; Bertrand, C.; Landry, Y.

in Journal of Pharmacology and Experimental Therapeutics (1987), 243(1), 310-6

See detailAirway epithelium releases a relaxant factor: demonstration with substance P
Tschirhart, Eric; Landry, Y.

in European Journal of Pharmacology (1987), 132(1), 103-4

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