Systems Ecology Group

The Systems Ecology group at the LCSB

Back row from left to right: Paul Wilmes (PI), Kristopher Schmit, Jean-Pierre Trezzi, Susheel Bhanu Busi, Benoît Kunath, Kacy Greenhalgh, Malte Herold, Antoine Malabirade, Dominik Ternes, Javier Ramiro Garcia, Cedric Laczny
Middle row from left to right: Janine Habier, Catherine Sedrani, Lea Grandmougin, Rashi Halder, Camille Martin-Gallausiaux, Francesco Delogu, Laura De Nies, Pedro Texeira Queiros
Front row from left to right: Laura Lebrun, Annegrät Daujeumont, Charlotte De Rudder, Audrey Frachet Bour, Loulou Peisl, Susana Marinez, Jessica Karta

About the Systems Ecology Group

We are embedded in a microbial world. Naturally occurring microbial communities play fundamental roles in the Earth’s biogeochemical cycles as well as in human health and disease, and provide essential services to mankind. Microbial consortia represent highly dynamic and heterogeneous systems, which exhibit enormous complexity at all levels.

We are using a Systems Biology approach to study mixed microbial communities in unprecedented detail. Microbial consortia of primary study include human host-associated microbiota and lipid accumulating microbial communities. Samples are routinely analysed in a systematic manner using integrated omics, comprising metagenomics, metatranscriptomics, metaproteomics and metabolomics. The resulting data is integrated and serves as input for the construction of multiscale models. The models allow formulation and testing of hypotheses which can be further validated using wet-lab experiments for example in a newly developed microfluidics-based human-microbial co-culture device and single-cell approaches.

Please consult our page regarding the individual research projects of the group.

The Systems Ecology Research Group was established under the auspices of the Luxembourg National Research Fund's ATTRACT Programme.