Paul Antony

Paul Antony

Postdoctoral researcher / Research associate

Sujets de recherche Systems Biomedicine, Neurodegeneration, Molecular Biology, Cell culture, Animal models
Faculté ou Centre Luxembourg Centre for Systems Biomedicine
Adresse postale Université du Luxembourg
6, avenue du Swing
L-4367 Belvaux
Bureau sur le campus BioTech II, 3.15
E-mail
Téléphone (+352) 46 66 44 6986
Video Dr. Paul Antony (LCSB)
Dr. Paul Antony (LCSB)
 
Dr. Paul Antony (LCSB)

Postdoc in the Clinical & Experimental Neuroscience group (Krüger Lab)

Last updated on: jeudi 15 février 2018

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2020

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See detailImpaired Mitochondrial-Endoplasmic Reticulum Interaction and Mitophagy in Miro1-Mutant Neurons in Parkinson’s Disease
Berenguer-Escuder, Clara; Grossmann, Dajana; Antony, Paul; Arena, Giuseppe; Wasner, Kobi; Massart, François; Jarazo, Javier; Walter, Jonas; Schwamborn, Jens Christian; Grünewald, Anne; Krüger, Rejko

in Human Molecular Genetics (2020)

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See detailMachine learning-assisted neurotoxicity prediction in human midbrain organoids
Monzel, Anna Sophia; Hemmer, K; Smits, Lisa; Bolognin, Silvia; Lucarelli, P; Rosety, Isabel; Zagare, Alise; Antony, Paul; Nickels, SL; Krüger, Rejko; Schwamborn, Jens Christian

in Parkinsonism and Related Disorders (2020)

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2019

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See detailAutomated high-throughput high-content autophagy and mitophagy analysis platform
Arias, Jonathan; Jarazo, Javier; Walter, Jonas; Gomez Giro, Gemma; Forster, Julia; Antony, Paul; Krüger, Rejko; Schwamborn, Jens Christian

in Scientific Reports (2019)

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See detailVariants in Miro1 cause alterations of ER-mitochondria contact sites in fibroblasts from Parkinson's disease patients
Berenguer, Clara; Grossmann, Dajana; Massart, François; Antony, Paul; Burbulla, Lena; Glaab, Enrico; Imhoff, Sophie; Trinh, Joanne; Seibler, Philip; Grünewald, Anne; Krüger, Rejko

in Journal of Clinical Medicine (2019)

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See detailFrom tech to bench: Deep Learning pipeline for image segmentation of high-throughput high-content microscopy data
Garcia Santa Cruz, Beatriz; Jarazo, Javier; Saraiva, Claudia; Gomez Giro, Gemma; Modamio Chamarro, Jennifer; Sabaté Soler, Sonia; Kyriaki, Barmpa; Antony, Paul; Schwamborn, Jens Christian; Hertel, Frank; Husch, Andreas

Poster (2019, November 29)

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See detailTranscriptome profiling data reveals Ubiquitin-Specific Peptidase 9 knockdown effects
Glaab, Enrico; Antony, Paul; Köglsberger, Sandra; Forster, Julia I.; Cordero-Maldonado, Maria L.; Crawford, Alexander; Garcia, Pierre; Buttini, Manuel

in Data in Brief (2019), 25(1), 104130

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See detailMutations in RHOT1 disrupt ER-mitochondria contact sites interfering with calcium homeostasis and mitochondrial dynamics in Parkinson's disease.
Grossmann, Dajana; Berenguer, Clara; Bellet, Marie Estelle; Scheibner, David; Bohler, Jill; Massart, François; Rapaport, Doron; Skupin, Alexander; Fouquier d'Hérouël, Aymeric; Sharma, Manu; Ghelfi, Jenny; Rakovic, Aleksandar; Lichtner, Peter; Antony, Paul; Glaab, Enrico; May, Patrick; Dimmer, Kai Stefan; Fitzgerald, Julia Catherine; Grünewald, Anne; Krüger, Rejko

in Antioxidants & redox signaling (2019)

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See detailImpaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients
Nickels, Sarah; Walter, Jonas; Bolognin, Silvia; Gerard, Deborah; Jaeger, Christian; Qing, Xiaobing; Tisserand, Johan; Jarazo, Javier; Hemmer, Kathrin; Harms, Amy; Halder, Rashi; Lucarelli, Philippe; Berger, Emanuel; Antony, Paul; Glaab, Enrico; Hankemeier, Thomas; Klein, Christine; Sauter, Thomas; Sinkkonen, Lasse; Schwamborn, Jens Christian

in Parkinsonism and Related Disorders (2019)

See detailSingle-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids
Smits, Lisa; Magni, Stefano; Grzyb, Kamil; Antony, Paul; Krüger, Rejko; Skupin, Alexander; Bolognin, Silvia; Schwamborn, Jens Christian

E-print/Working paper (2019)

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See detailModeling Parkinson’s disease in midbrain-like organoids
Smits, Lisa; Reinhardt, Lydia; Reinhardt, Peter; Glatza, Michael; Monzel, Anna Sophia; Stanslowsky, Nancy; Rosato-Siri, Marcelo; Zanon, Alessandra; Antony, Paul; Bellmann, Jessica; Nicklas, Sarah; Hemmer, Kathrin; Qing, Xiaobing; Berger, Emanuel; Kalmbach, Norman; Ehrlich, Marc; Bolognin, Silvia; Hicks, Andrew; Wegner, Florian; Sterneckert, Jared; Schwamborn, Jens Christian

in NPJ Parkinson's Disease (2019)

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See detailNeural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality
Walter, Jonas; Bolognin, Silvia; Antony, Paul; Nickels, Sarah; Poovathhingal, Suresh; Salamanca, Luis; Magni, Stefano; Perfeito, Rita; Hoel, Fredrik; Qing, Xiaobing; Jarazo, Javier; Arias-Fuenzalida, Jonathan; Ignac, Tomasz; Monzel, Anna Sophia; Gonzalez-Cano, Laura; Pereira de Almeida, Luis; Skupin, Alexander; Tronstad, Karl; Schwamborn, Jens Christian

in Stem Cell Reports (2019)

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2018

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See detailMillifluidic culture improves human midbrain organoid vitality and differentiation
Berger, Emanuel; Magliaro, Chiara; Paczia, Nicole; Monzel, Anna Sophia; Antony, Paul; Linster, Carole; Bolognin, Silvia; Ahluwalia, Arti; Schwamborn, Jens Christian

in Lab on a Chip - Miniaturisation for Chemistry and Biology (2018)

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See detail3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing
Bolognin, Silvia; Fossépré, Marie; Qing, Xiaobing; Jarazo, Javier; Ščančar, Janez; Lucumi Moreno, Edinson; Nickels, Sarah; Wasner, Kobi; Ouzren, Nassima; Walter, Jonas; Grünewald, Anne; Glaab, Enrico; Salamanca, Luis; Fleming, Ronan M. T.; Antony, Paul; Schwamborn, Jens Christian

in Advanced Science (2018)

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See detailA rare loss-of function variant of ADAM17 is associated with late-onset familial Alzheimer disease
Hartl, Daniela; May, Patrick; Gu, Wei; Mayhaus, Manuel; Pichler, Sabrina; Spaniol, Christian; Glaab, Enrico; Bobbili, Dheeraj Reddy; Antony, Paul; Köglsberger, Sandra; Kurz, Alexander; Grimmer, Timo; Morgan, Kevin; Vardarajan, Badri N.; Reitz, Christiane; Hardy, John; Bras, Jose; Guerreiro, Rita; AESG; Balling, Rudi; Schneider, Jochen; Riemenschneider, Matthias

in Molecular Psychiatry (2018)

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2017

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See detailIDENTIFICATION OF A RARE GENE VARIANT THAT IS ASSOCIATED WITH FAMILIAL ALZHEIMER DISEASE AND REGULATES APP EXPRESSION
Hartl, Daniela; May, Patrick; Gu, Wei; Mayhaus, Manuel; Glaab, Enrico; Antony, Paul; Bobbili, Dheeraj Reddy; Köglsberger, Sandra; Pichler, Sabrina; Spaniol, Christian; Kurz, Alexander; Balling, Rudi; Schneider, Jochen; Riemenschneider, Matthias

in Alzheimer's & Dementia : The Journal of the Alzheimer's Association (2017), 13(7, Supplement), 648

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See detailGender-specific expression of ubiquitin-specific peptidase 9 modulates tau expression and phosphorylation: possible implications for tauopathies
Köglsberger, Sandra; Cordero Maldonado, Maria Lorena; Antony, Paul; Forster, Julia; Garcia, Pierre; Buttini, Manuel; Crawford, Alexander Dettmar; Glaab, Enrico

in Molecular Neurobiology (2017), 54(10), 79797993

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2016

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See detailCharacterization of Differentiated SH-SY5Y as Neuronal Screening Model Reveals Increased Oxidative Vulnerability
Antony, Paul; Forster, Julia; Köglsberger, Sandra; Trefois, Christophe; Boyd, Olga; Baumuratov, Aidos; Balling, Rudi; Buck, L

in Journal of Biomolecular Screening : The Official Journal of the Society for Biomolecular Screening (2016)

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See detailGene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in Mammalian Macrophages
Antony, Paul; Tallam, Aravind; Perumal, Thanneer Malai; Jäger, Christian; Fritz, Joëlle; Balling, Rudi; del Sol Mesa, Antonio; Michelucci, Alessandro; Vallar, Laurent

in PLoS ONE (2016)

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See detailEnteric neurons from Parkinson's disease patients display ex vivo aberrations in mitochondrial structure.
Baumuratov, Aidos; Antony, Paul; Ostaszewski, Marek; He, F.; Salamanca Mino, Luis; Antunes, L.; Weber, J.; Longhino, L.; Derkinderen, P.; Koopman, W. J. H.; Diederich, N. J.

in Scientific reports (2016), 6

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2015

See detailStaining for unphosphorylated alpha-synuclein in the colon mucosa. No difference between patients with Parkinson's disease and healthy controls
Antony, Paul; Antunes, L; Frasquilho, S; Ostaszewski, Marek; Weber, J; Longhino, L; Baumuratov, Aidos; Derkinderen, P; Balling, Rudi; Diederich, Nico

Scientific Conference (2015, June)

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See detailPlatelet mitochondrial membrane potential in Parkinson's disease.
Antony, Paul; Boyd, Olga; Trefois, Christophe; Ammerlaan, Wim; Ostaszewski, Marek; Baumuratov, Aidos S.; Longhino, Laura; Antunes, Laurent; Koopman, Werner; Balling, Rudi; Diederich, Nico J.

in Annals of clinical and translational neurology (2015), 2(1), 67-73

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See detailEvaluation of Cell Line Suitability for Disease Specific Perturbation Experiments.
Biryukov, Maria; Antony, Paul; Krishna, Abhimanyu; May, Patrick; Trefois, Christophe

in Lausen, Berthold; Krolak-Schwerdt, Sabine; Böhmer, Matthias (Eds.) Data Science, Learning by Latent Structures, and Knowledge Discovery (2015, February 20)

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See detailCritical transitions in chronic disease: transferring concepts from ecology to systems medicine
Trefois, Christophe; Antony, Paul; Goncalves, Jorge; Skupin, Alexander; Balling, Rudi

in Current Opinion in Biotechnology (2015), 34

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2014

See detailAnalysis of mitochondrial membrane potential in idiopathic Parkinson's disease: A case-control study
Antony, Paul; Boyd, Olga; Trefois, Christophe; Ostaszewski, Marek; Baumuratov, Aidos; Balling, Rudi; Diederich, Nico

Scientific Conference (2014, June 12)

See detailCuration of complex molecular pathways of Parkinson's disease as a collaborative scientific community effort
Antony, Paul; Ostaszewski, Marek; Gawron, P; Trefois, Christophe; Fujita, K.A.; Mosch, Sabine; Balling, Rudi

Scientific Conference (2014, June 12)

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See detailIntegrating Pathways of Parkinson's Disease in a Molecular Interaction Map
Fujita, Kazuhiro A.; Ostaszewski, Marek; Matsuoka, Yukiko; Ghosh, Samik; Glaab, Enrico; Trefois, Christophe; Crespo, Isaac; Perumal, Thanneer Malai; Jurkowski, Wiktor; Antony, Paul; Diederich, Nico; Buttini, Manuel; Kodama, Akihiko; Satagopam, Venkata; Eifes, Serge; del Sol Mesa, Antonio; Schneider, Reinhard; Kitano, Hiroaki; Balling, Rudi

in Molecular Neurobiology (2014)

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See detailSystems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson’s disease
Krishna, Abhimanyu; Biryukov, Maria; Trefois, Christophe; Antony, Paul; Hussong, Rene; Lin, Jake; Heinäniemi, Merja; Glusman, Gustavo; Köglsberger, Sandra; Boyd, Olga; van den Berg, Bart H.J.; Linke, Dennis; Huang, David; Wang, Kai; Hood, Leroy; Tholey, Andreas; Schneider, Reinhard; Galas, David J.; Balling, Rudi; May, Patrick

in BMC Genomics (2014), 15(1154),

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See detailAutomated nuclei clump splitting by combining local concavity orientation and graph partitioning
Samsi, Siddharth; Trefois, Christophe; Antony, Paul; Skupin, Alexander

in International Conference on Biomedical and Health Informatics (2014)

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2013

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See detailThe hallmarks of Parkinson's disease.
Antony, Paul; Diederich, Nico; Krüger, Rejko; Balling, Rudi

in FEBS Journal (2013)

See detailDifferentiated SH-SY5Y Cells as PD Model for Mitochondrial Dysfunction: From Whole Genome Sequencing to an Educated Design of High-Throughput Experiments
Antony, Paul; Krishna, Abhimanyu; May, Patrick; Trefois, Christophe; Boyd, Olga; Köglsberger, Sandra; Baumuratov, Aidos; Galas, David J.; Balling, Rudi

Poster (2013)

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See detailLight microscopy applications in systems biology: opportunities and challenges.
Antony, Paul; Trefois, Christophe; Stojanovic, Aleksandar; Baumuratov, Aidos; Kozak, Karol

in Cell Communication and Signaling (2013), 11(1), 1-19

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See detailThe Parkinson's Disease Map: A Framework for Integration, Curation and Exploration of Disease-related Pathways
Ostaszewski, Marek; Fujita, Kazuhiro; Matsuoka, Yukiko; Ghosh, Samik; Glaab, Enrico; Trefois, Christophe; Crespo, Isaac; Perumal, Thanneer Malai; Jurkowski, Wiktor; Antony, Paul; Diederich, Nico; Buttini, Manuel; Kolodkin, Alexey; Kodama, Akihiko; Satagopam, Venkata; Biryukov, Maria; Eifes, Serge; del Sol Mesa, Antonio; Schneider, Reinhard; Kitano, Hiroaki; Balling, Rudi

Poster (2013, March 09)

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2012

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See detailFrom Systems Biology to Systems Biomedicine
Antony, Paul; Balling, Rudi; Vlassis, Nikos

in Current Opinion in Biotechnology (2012), 23(4), 604-8

See detailConstructing a comprehensive map of Parkinson’s disease to elucidate underlying mechanisms of its multifaceted molecular pathology
Trefois, Christophe; Fujita, A. K.; Ostaszewski, Marek; Matsuoka, Yukiko; Ghosh, Samic; Glaab, Enrico; Crespo, Isaac; Perumal, T. M.; Jurkowski, Wiktor; Antony, Paul; Diederich, Nico; Buttini, Manuel; Kodama, Akihiko; Satagopam, Venkata; Eifes, Serge; del Sol Mesa, Antonio; Schneider, Reinhard; Kitano, Hiroaki; Balling, Rudi

Poster (2012, August)

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2011

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See detailParkinson’s disease mouse models in translational research
Antony, Paul; Diederich, Nico; Balling, Rudi

in Mammalian Genome : Official Journal of the International Mammalian Genome Society (2011), 22(7-8), 401-19

See detailAnalysis of critical transitions in Parkinson's disease
Trefois, Christophe; Antony, Paul; Baumuratov, Aidos; Boyd, Olga; Köglsberger, Sandra; Balling, Rudi

Poster (2011, December 12)

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2009

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See detailIdentification and functional dissection of localization signals within ataxin-3.
Antony, Paul; Mäntele, Simone; Mollenkopf, Phillip; Boy, Jana; Kehlenbach, Ralph; Riess, Olaf; Schmidt, Thorsten

in Neurobiology of Disease (2009), 36(2), 280-92

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2007

See detailLocalization signals within ataxin-3 influence the formation of intranuclear aggregates in spinocerebellar ataxia type 3
Antony, Paul; Boy, J; Henderson, B; Stamminger, T; Rieß, O; Schmidt, T

in Aktuelle Neurologie (2007)

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2006

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