After being the director of the LCSB for 12 years, Prof. Rudi Balling is retiring. For this very special occasion, the LCSB is organising a Goodbye lecture series to honour him. This lecture series brings together internationally renowned scientists from different disciplines who will share their perspectives on major challenges of future scientific research and interdisciplinary approaches to solve them.
The fourth lecture will take place online on 7 October.
Speaker : Dr Sara-Jane Dunn
Biological Computation in Stem Cells
Experimental biology has proven our ability to induce cell identity via differentiation or reprogramming, offering huge promise for medicine and the study of development. Yet despite this wealth of research, an explanation of how cell state conversions arise remains fragmentary. Ideally, we would like to understand the complex, dynamic interplay of genetic components that manifests as cell fate conversions. To address this gap, computational analyses can be combined with mathematical modelling to interrogate experimental data and generate testable hypotheses on how a program of genetic interactions governs cell identity. In this talk, I will demonstrate how interdisciplinary approaches have revealed the biological program governing fate decisions in stem cells, and indeed, could be used in other domains to expose the regulatory programs that drive cellular decision-making more broadly. (Download the poster)
Meeting number: 188 257 9961
Meeting password: CCsq8xdn2g4
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More information about the full programme of the lecture series