Dr. Lisa Smits
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| Faculté ou Centre | Luxembourg Centre for Systems Biomedicine | ||||
| Department | LCSB Operations | ||||
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Université du Luxembourg 6, avenue du Swing L-4367 Belvaux |
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| Bureau sur le campus | BioTech II, 2.07 | ||||
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| Téléphone | (+352) 46 66 44 6038 | ||||
Lisa started her first research project at the LCSB in 2014. After obtaining her PhD in Neurobiology, she joined the LCSB administrative staff to support the communication team. Today, she is part of the university's Fundraising Office and acts as a Fundraiser for the LCSB.
Last updated on: vendredi 17 janvier 2020
2022
Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression; ; ; ; ; ; ; ;
in American Journal of Human Genetics (2022)
2021
A new brain organoid model to study Parkinson’s Disease; ; ; ; ; ; ; ;
in Biomedical Science and Engineering (2021)
Parkinson’s disease phenotypes in patient neuronal cultures and brain organoids improved by 2-Hydroxypropyl-b-Cyclodextrin treatment; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ;
in Movement Disorders (2021)
The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ;
in Cell Reports (2021)
2020
Machine learning-assisted neurotoxicity prediction in human midbrain organoids; ; ; ; ; ; ; ; ; ;
in Parkinsonism and Related Disorders (2020)
Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids; ; ; ; ; ; ; ; ; ;
in Cell and Tissue Research (2020)
Midbrain organoids: A new tool to investigate Parkinson's disease;
in Frontiers in Cell and Developmental Biology (2020)
2019
Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids; ; ; ; ; ; ;
E-print/Working paper (2019)
Modeling Parkinson’s disease in midbrain-like organoids; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ;
in NPJ Parkinson's Disease (2019)
Cultivation and characterization of human midbrain organoids in sensor integrated microfluidic chips; ; ; ; ; ; ; ; ;
E-print/Working paper (2019)
2018
In vivo Phenotyping of Human Parkinson’s Disease-Specific Stem Cells Carrying the LRRK2-G2019S Mutation Reveals Increased a-Synuclein Levels but Absence of Spreading; ; ;
in Opera Medica et Physiologica (2018)
Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity; ; ; ; ; ; ; ; ; ; ; ;
in Acta Neuropathologica Communications (2018)
2017
Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells; ; ; ; ; ; ; ; ; ; ; ; ;
in Stem Cell Reports (2017)
Nurr1:RXRα heterodimer activation as monotherapy for Parkinson’s disease; ; ; ; ; ; ; ; ; ; ; ; ; ;
in Proceedings of the National Academy of Sciences of the United States of America (2017)
