Kamil Grzyb

Postdoctoral researcher

Faculté ou Centre Luxembourg Centre for Systems Biomedicine
Department Scientific Central Services
Adresse postale Campus Belval, Université du Luxembourg
7, Avenue des Hauts Fourneaux
L-4362 Esch-sur-Alzette
Bureau sur le campus BioTech I, 5.09B
E-mail
Téléphone (+352) 46 66 44 6118

Postdoc in the Integrative Cell Signalling group (Skupin Lab)

Last updated on: vendredi 14 juin 2019

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2022

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See detailSingle-cell transcriptional profiling and gene regulatory network modeling in Tg2576 mice reveal gender-dependent molecular features preceding Alzheimer-like pathologies
Ali, Muhammad; Huarte, Oihane; Heurtaux, Tony; Garcia, Pierre; Rodriguez, Beatriz Pardo; Grzyb, Kamil; Halder, Rashi; Skupin, Alexander; Buttini, Manuel; Glaab, Enrico

in Molecular Neurobiology (2022), in press (doi:10.1007/s12035-022-02985-2)(in press),

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See detailStress hormone signalling inhibits Th1 polarization in a CD4 T-cell-intrinsic manner via mTORC1 and the circadian gene PER1
Capelle, Christophe M.; Chen, Anna; Zeng, Ni; Baron, Alexandre; Grzyb, Kamil; Arns, Thais; Skupin, Alexander; Ollert, Markus; He, Feng

in Immunology (2022), 165(4), 428--444

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See detailCombinatorial analysis reveals highly coordinated early-stage immune reactions that predict later antiviral immunity in mild COVID-19 patients
Capelle, Christophe M.; Ciré, Séverine; Domingues, Olivia; Ernens, Isabelle; Hedin, Fanny; Fischer, Aurélie; Snoeck, Chantal J.; Ammerlaan, Wim; Konstantinou, Maria; Grzyb, Kamil; Skupin, Alexander; Carty, Cara L.; Hilger, Christiane; Gilson, Georges; Celebic, Aljosa; Wilmes, Paul; Del Sol, Antonio; Kaplan, Ian M.; Betsou, Fay; Abdelrahman, Tamir; Cosma, Antonio; Vaillant, Michel; Fagherazzi, Guy; Ollert, Markus; He, Feng

in Cell Reports Medicine (2022), 3(4), 100600

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See detailSingle-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson’s disease
Novak, Gabriela; Kyriakis, Dimitrios; Grzyb, Kamil; Bernini, Michela; Rodius, Sophie; Dittmar, Gunnar; Finkbeiner, Steven; Skupin, Alexander

in Communications Biology (2022), 5(1), 1--19

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See detailMidbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression
Zagare, Alise; Barmpa, Kyriaki; Smajic, Semra; Smits, Lisa; Grzyb, Kamil; Grünewald, Anne; Skupin, Alexander; Nickels, Sarah Louise; Schwamborn, Jens Christian

in American Journal of Human Genetics (2022)

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2021

See detailA new brain organoid model to study Parkinson’s Disease
Bolognin, Silvia; Smits, Lisa; Nickels, Sarah Louise; Magni, Stefano; Antony, Paul; Grzyb, Kamil; Krüger, Rejko; Skupin, Alexander; Schwamborn, Jens Christian

in Biomedical Science and Engineering (2021)

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See detailSingle‑nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell‑type‑specific gene regulatory variation
Gui, Yujuan; Grzyb, Kamil; Thomas, Melanie; Ohnmacht, Jochen; Garcia, Pierre; Buttini, Manuel; Skupin, Alexander; Sauter, Thomas; Sinkkonen, Lasse

in Epigenetics and Chromatin (2021)

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See detailSingle-Cell Transcriptomics and In Situ Morphological Analyses Reveal Microglia Heterogeneity Across the Nigrostriatal Pathway
Uriarte Huarte, Oihane; Kyriakis, Dimitrios; Heurtaux, Tony; Pires-Afonso, Yolanda; Grzyb, Kamil; Halder, Rashi; Buttini, Manuel; Skupin, Alexander; Mittelbronn, Michel; Michelucci, Alessandro

in Frontiers in Immunology (2021)

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See detailThe Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1
Walter, Jonas; Bolognin, Silvia; Poovathingal, Suresh; Magni, Stefano; Gerard, Déborah; Antony, Paul; Nickels, Sarah Louise; Salamanca, Luis; Berger, Emanuel; Smits, Lisa; Grzyb, Kamil; Perfeito, Rita; Hoel, Fredrik; Qing, Xiaobing; Ohnmacht, Jochen; Bertacchi, Michele; Jarazo, Javier; Ignac, Tomasz; Monzel, Anna; Gonzalez-Cano, Laura; Krüger, Rejko; Sauter, Thomas; Studer, Michele; Pereira de Almeida, Luis; Tronstad, Karl; Sinkkonen, Lasse; Skupin, Alexander; Schwamborn, Jens Christian

in Cell Reports (2021)

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2020

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See detailPatient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.
Golebiewska, Anna; Hau, Ann-Christin; Oudin, Anaïs; Stieber, Daniel; Yabo, Yahaya A.; Baus, Virginie; Barthelemy, Vanessa; Klein, Eliane; Bougnaud, Sébastien; Keunen, Olivier; Wantz, May; Michelucci, Alessandro; Neirinckx, Virginie; Muller, Arnaud; Kaoma, Tony; Nazarov, Petr V.; Azuaje, Francisco; De Falco, Alfonso; Flies, Ben; Richart, Lorraine; Poovathingal, Suresh; Arns, Thais; Grzyb, Kamil; Mock, Andreas; Herold-Mende, Christel; Steino, Anne; Brown, Dennis; May, Patrick; Miletic, Hrvoje; Malta, Tathiane M.; Noushmehr, Houtan; Kwon, Yong-Jun; Jahn, Winnie; Klink, Barbara; Tanner, Georgette; Stead, Lucy F.; Mittelbronn, Michel; Skupin, Alexander; Hertel, Frank; Bjerkvig, Rolf; Niclou, Simone

in Acta Neuropathologica (2020)

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See detailPrimary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicine
Golebiewska, Anna; Hau, Ann-Christin; Oudin, Anais; Stieber, Daniel; Yabo, Yahaya A.; Baus, Virginie; Barthelemy, Vanessa; Klein, Eliane; Bougnaud, Sebastien; Keunen, Olivier; Wantz, May; Michelucci, Alessandro; Neirinckx, Virginie; Muller, Arnaud; Kaoma, Tony; Nazarov, Petr V.; Azuaje, Francisco; De Falco, Alfonso; Flies, Ben; Richart, Lorraine; Poovathingal, Suresh; Arns, Thais; Grzyb, Kamil; Mock, Andreas; Herold-Mende, Christel; Steino, Anne; Brown, Dennis; May, Patrick; Miletic, Hrvoje; Malta, Tathiane M.; Noushmehr, Houtan; Kwon, Yong-Jun; Jahn, Winnie; Klink, Barbara; Tanner, Georgette; Stead, Lucy F.; Mittelbronn, Michel; Skupin, Alexander; Hertel, Frank; Bjerkvig, Rolf; Niclou, Simone

E-print/Working paper (2020)

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See detailSingle-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids
Smits, Lisa; Magni, Stefano; Kinugawa, Kaoru; Grzyb, Kamil; Luginbühl, Joachim; Sabaté Soler, Sonia; Bolognin, Silvia; Shin, Jay; Mori, Eiichiro; Skupin, Alexander; Schwamborn, Jens Christian

in Cell and Tissue Research (2020)

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See detailNew insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome
Tiraboschi, Ettore; Martina, Silvia; van der Ent, Wietske; Grzyb, Kamil; Gawel, Kinga; Cordero-Maldonado, Maria Lorena; Poovathingal, Suresh Kumar; Heintz, Sarah; Satheesh, Somisetty Venkata; Brattespe, Jarle; Skupin, Alexander; Esguerra, Camila

in Epilepsia (2020)

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2019

See detailSingle-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids
Smits, Lisa; Magni, Stefano; Grzyb, Kamil; Antony, Paul; Krüger, Rejko; Skupin, Alexander; Bolognin, Silvia; Schwamborn, Jens Christian

E-print/Working paper (2019)

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2018

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See detailCaSiAn: a Calcium Signaling Analyzer tool
Moein, Mahsa; Grzyb, Kamil; Gonçalves Martins, Teresa; Komoto, Shinya; Peri, Francesca; Crawford, Alexander Dettmar; Fouquier d’Herouel, Aymeric; Skupin, Alexander

in Bioinformatics (2018), 1

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